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Key Challenges and Potential Solutions for Optimizing Downstream Bioprocessing Production

The term “optimize” is often applied to complex manufacturing, automation and business processes and implies that the most efficient function of all the elements of a process – technologies, sequences and procedures – has not been achieved. While no method can be perfect, every process can benefit from a careful consideration where new thinking, new techniques and new technology can yield significant improvements.

The dramatic growth in the use of biologics across multiple therapeutic applications and categories will only continue to increase. As the demand for these drugs accelerates, there are growing concerns about their cost and availability. Biologics manufacturers are investigating ways to address these concerns – and downstream production in bioprocessing operations is one such area.

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Solutions for bioprocessing

From the small-scale bench to full commercial manufacturing, we enable our customers to reach the market with new treatments for patients, faster and safer. Learn more about our offering for biopharmaceutical manufacturing.

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Authors

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Dr. Nandu Deorkar

Senior Vice President, Research & Development – Biopharma Production, Avantor

Nandu Deorkar is Senior Vice President, Biopharma Production Research & Development for Avantor. He is responsible for innovation strategy and planning, and execution of new products and technology development. During his more than 25-year career in research & development, Dr. Deorkar has been leading teams working on various aspects of upstream and downstream bioprocessing, single use systems, chemical/polymer R&D, drug development, formulation, drug delivery technologies, process development, and technology transfer. He has published more than 30 articles and holds more than 20 patents. Dr. Deorkar received Ph.D. from Indian Institute of Technology, Mumbai, India and MBA in Marketing from Fairleigh Dickinson University, Madison, NJ, USA.

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Claudia Berrón

Senior Vice President, Proprietary Research Products & Materials

Claudia Berrón is Avantor’s Senior Vice President, Senior Vice President, Proprietary Research Products & Materials. Prior to this, she was Senior Vice President, Business Development and Commercial Operations for our Biopharma Production business unit. Claudia has over two decades of experience in strategic marketing, covering ideation, value proposition strategies, market segmentation and planning through product and services launch into market. She has been with Avantor since 2015.

Claudia holds an MBA from the University of North Carolina Kenan-Flagler Business School and a bachelor’s degree from Monterrey Institute of Technology in Mexico City.