1354 Results for: "peptide synthesis"

Supplier: Chemglass

These unjacketed filter reactors can be used for single or multi-step reactions and filtrations in the same vessel, production and process scale peptide synthesis.

Supplier: Supra Sciences

Solid supported primary amine utilized in solid phase synthesis for coupling amino acids at carboxyl terminus.

Supplier: CHEM-IMPEX INTERNATIONAL, INC

1,1'-Carbonyldiimidazole is mainly employed to convert alcohols and amines into carbamates, esters, and ureas. It is also used in the synthesis of peptides and nucleoside triphosphates.

Supplier: CHEM-IMPEX INTERNATIONAL, INC

Boc-Gly-Gly-OH, also known as N-Boc-Glycylglycine, is a versatile dipeptide derivative widely utilized in peptide synthesis and pharmaceutical research. This compound features a tert-butoxycarbonyl (Boc) protecting group, which enhances its stability and solubility, making it an ideal choice for various applications in organic synthesis. Researchers often employ Boc-Gly-Gly-OH in the development of peptide-based therapeutics, as it serves as a building block for more complex peptide structures. Its unique properties allow for selective deprotection, facilitating the synthesis of peptides with desired functionalities. In addition to its role in peptide synthesis, Boc-Gly-Gly-OH is also valuable in the study of biological processes and drug design. Its ability to mimic natural peptides makes it a useful tool in the exploration of peptide-receptor interactions. The compound's favorable characteristics, such as its ease of handling and compatibility with various coupling reagents, further enhance its appeal to researchers and industry professionals. Whether in academic research or industrial applications, Boc-Gly-Gly-OH stands out as a reliable and effective compound for advancing peptide chemistry.

Supplier: Corning

Chloramphenicol is a common antibiotic which inhibits microbial protein synthesis by preventing peptide bond formation. It is effective against Gram-positive and Gram-negative bacteria.

Supplier: CHEM-IMPEX INTERNATIONAL, INC

Fmoc-Gly-Pro-OH is a valuable building block in peptide synthesis, particularly favored for its role in solid-phase peptide synthesis (SPPS). This compound, also known as Fmoc-glycine proline hydroxyl, features a fluorenylmethoxycarbonyl (Fmoc) protecting group that allows for selective deprotection during synthesis, making it an essential tool for researchers and industry professionals in the field of biochemistry and pharmaceuticals. Its unique structure enhances stability and solubility, facilitating the formation of complex peptides and proteins. This compound is particularly useful in the development of therapeutic peptides and proteins, enabling the creation of bioactive molecules with specific functionalities. Researchers have successfully utilized Fmoc-Gly-Pro-OH in the synthesis of peptide-based drugs and in studies related to protein folding and interactions. Its ability to provide a stable backbone while allowing for functional group modifications makes it a preferred choice for those looking to innovate in peptide design and development. With its proven track record in various applications, Fmoc-Gly-Pro-OH stands out as a reliable and efficient reagent for advancing peptide chemistry.

Supplier: CHEM-IMPEX INTERNATIONAL, INC

Fmoc-Ala-Ala-OH is a highly regarded compound in the field of peptide synthesis, known for its role as a versatile building block in the development of peptides and proteins. This compound features a fluorenylmethoxycarbonyl (Fmoc) protecting group, which is essential for the selective protection of amino groups during the synthesis process. Its unique structure allows for efficient coupling reactions, making it an ideal choice for researchers and professionals engaged in peptide chemistry. Fmoc-Ala-Ala-OH is particularly useful in the synthesis of dipeptides and can be employed in various applications, including drug development, bioconjugation, and the design of peptide-based therapeutics. Its stability and compatibility with standard coupling reagents enhance its utility in complex peptide assembly, providing a reliable option for achieving high yields in synthetic processes. Moreover, Fmoc-Ala-Ala-OH stands out due to its ease of use and the ability to facilitate the synthesis of peptides with specific sequences, which is crucial for the development of targeted therapies. Researchers appreciate its effectiveness in generating peptides that can be utilized in a range of applications, from basic research to advanced therapeutic solutions. With its proven track record in peptide synthesis, Fmoc-Ala-Ala-OH is an indispensable tool for professionals looking to innovate in the fields of biochemistry and pharmacology.

Supplier: Honeywell Research Chemicals

BioSyn« products are ideal for DNA, RNA and oligonucleotide synthesis. All solvents and regents are filtered (0.2-micron) and tested for oxidation reage.

Supplier: Adipogen

Efficient coupling reagent for the synthesis of sterically hindered amides, especially peptides. In terms of reactivity and racemization-suppressing capability, this pyridinium-type reagent, BEP, proved to be more efficient than commonly used uronium- and phosphonium-type reagents, such as HBTU, BOP, and PyBroP, for the synthesis of hindered peptides containing N-methylated or Calpha,Calpha-dialkylated amino acid residues. BEP was also proven to be an efficient reagent for the synthesis of esters, especially active esters and hindered esters, and tert-butyl esters.

Supplier: Honeywell Research Chemicals

BioSyn products are ideal for DNA, RNA and oligonucleotide synthesis. All solvents and regents are filtered (0.2-micron) and tested for oxidation reage.

Supplier: CHEM-IMPEX INTERNATIONAL, INC

Boc-Gly-Gly-Gly-OH, also known as N-Boc-Glycylglycylglycine, is a versatile peptide derivative that plays a significant role in peptide synthesis and drug development. This compound is particularly valued in the pharmaceutical and biochemistry sectors for its ability to serve as a building block in the synthesis of more complex peptides. Its unique structure, featuring three glycine residues, enhances its solubility and stability, making it an ideal candidate for various applications, including the development of peptide-based therapeutics and research into protein interactions. Researchers utilize Boc-Gly-Gly-Gly-OH in the preparation of peptide libraries, enabling the exploration of new drug candidates and therapeutic agents. Its protective Boc (tert-butyloxycarbonyl) group allows for selective deprotection, facilitating the stepwise assembly of peptides. This compound's compatibility with solid-phase peptide synthesis (SPPS) further underscores its importance in the field, as it streamlines the process of creating complex peptide structures. With its robust applications and ease of use, Boc-Gly-Gly-Gly-OH is an essential tool for professionals engaged in peptide research and development.

Supplier: Prosci

LASS6 Antibody: The LASS (longevity assurance homolog) family members represent a subgroup of the homeobox gene family and are highly conserved from yeasts to mammals. Six members of this family of proteins have been characterized (LASS1-6) and all are involved in ceramide synthesis during cell growth regulation and cancer differentiation. Like the highly homologous LASS5, LASS6 is also an endoplasmic reticulum, multi-pass membrane protein. LASS6 is also involved in the synthesis of C14, C16 and C18-ceramide, but shows a preference for unsaturated fatty acids. LASS6 is broadly expressed in a wide range of tissues and microarray data suggests that it may play a role in cancer differentiation and early embryonic development.

Supplier: Bachem Americas

Useful for the synthesis of peptide amides using Fmoc strategy. Cleavage has been performed with 50 % TFA in CH₂Cl₂ or 95% aqueous TFA. Scavengers may be required.

Supplier: New England Biolabs (NEB)

BG-GLA-NHS is an amine-reactive building block for the one-step synthesis of SNAP-tag® substrates from amine-containing precursors including proteins, peptides or oligonucleotides

Supplier: Honeywell Research Chemicals

BioSyn« products are ideal for DNA, RNA and oligonucleotide synthesis. All solvents and regents are filtered (0.2-micron) and tested for oxidation reage.

Supplier: Prosci

SCO2 Antibody: Synthesis of cytochrome c oxidase 2 was initially identified in yeast as one of two cytochrome c oxidase (COX) assembly proteins that enable the assembly of cytochrome c holoenzyme, a complex that catalyzes the transfer of reducing equivalents from cytochrome c to molecular oxygen and pumps protons across the inner mitochondrial membrane. Like their yeast homologs, the function of both SCO2 and SCO1 are dependent on copper ion binding. Recent studies suggest that SCO2 expression is regulated by p53, so that a decrease in p53 expression, such as in numerous tumors and cells lines, the drop in SCO2 expression leads to a shift from normal aerobic respiration towards the production of glycolytic ATP. Defects in the SCO2 protein are also associated with fatal infantile cardioencephalomyopathy and COX deficiency.

Supplier: Prosci

LASS5 Antibody: The LASS (longevity assurance homolog) family members represent a subgroup of the homeobox gene family and are highly conserved from yeasts to mammals. Six members of this family of proteins have been characterized (LASS1-6) and all are involved in ceramide synthesis during cell growth regulation and cancer differentiation. LASS5, also called Trh4, is a 392 amino acid endoplasmic reticulum, multi-pass membrane protein. Functioning as a dihydro-ceramide synthase, LASS5 is involved in the production of sphingolipids containing mainly one fatty acid donor (N-linked palmitoyl-ceramide) in a fumonisin B1-independent manner. It uses palmitoyl-CoA as an acyl donor and is involved in the synthesis of C14, C16 and C18-ceramide. LASS5 is the most abundantly expressed and predominant ceramide synthase isoform in lung epithelia. Recent studies show that LASS5 partially correct growth and apoptosis.

Supplier: CHEM-IMPEX INTERNATIONAL, INC

Boc-Ala-Ala-OH, also known as N-Boc-L-alanyl-L-alanine, is a valuable dipeptide derivative widely utilized in peptide synthesis and pharmaceutical research. This compound features a tert-butoxycarbonyl (Boc) protecting group, which enhances its stability and solubility, making it an ideal choice for researchers engaged in the development of peptide-based therapeutics. Its unique structure allows for selective reactions, facilitating the synthesis of more complex peptides and proteins. In the pharmaceutical industry, Boc-Ala-Ala-OH serves as a crucial intermediate in the preparation of bioactive peptides, which are essential for drug development and therapeutic applications. Its ability to protect amino groups during synthesis while maintaining reactivity makes it a preferred choice for chemists aiming to streamline their workflows. Additionally, its applications extend to the fields of biochemistry and molecular biology, where it is used in the study of protein interactions and enzyme activity. The compound's versatility and efficiency in peptide synthesis underscore its significance in advancing research and development in various scientific domains.

Supplier: Prosci

SCO1 Antibody: Synthesis of cytochrome c oxidase 1 was initially identified in yeast as one of two cytochrome c oxidase (COX) assembly proteins that enable the assembly of cytochrome c holoenzyme, a complex that catalyzes the transfer of reducing equivalents from cytochrome c to molecular oxygen and pumps protons across the inner mitochondrial membrane. Like their yeast homologs, the function of both SCO1 and SCO2 are dependent on copper ion binding. Mutations in either gene can lead to cytochrome c oxidase respiratory chain defects, with a missense mutation in human SCO1 (P174L) associated with a fatal neonatal hepatopathy when the second allele is also non-functional, suggesting the pathology is due to loss of function. It has been suggested that this mutation alters the SCO1 affinity for the copper (I) ion, thus impairing the efficiency of copper transfer to the cytochrome c oxidase. At least two isoforms of SCO1 are known to exist and both are recognized by the SCO1 antibody. This SCO1 antibody has no cross-reactivity to SCO2.

Supplier: Bachem Americas

A very acid sensitive resin suitable for the synthesis of protected peptide fragments by the Fmoc-strategy. ClTrt resin is in particular suitable for the preparation of C-terminal prolyl and cysteinyl peptides (please see 2-Chlorotrityl Chloride Resin-Linked Amino Acids). Release from this resin is achieved by using 1-50 % TFA in CH₂Cl₂ containing 8 % triisopropylsilane, AcOH/CF₃CH₂OH/CH₂Cl₂, 0.5 % TFA or hexafluoroisopropanol/CH₂Cl₂. ClTrt resin has been used in cyclization reactions under Heck reaction conditions, the solid phase synthesis of β-peptides via the Arndt-Eistert homologation of Fmoc-protected amino acid diazoketones and in Mannich reactions of alkynes, secondary amines and aldehydes in the presence of a copper (I) salt affording the corresponding aminomethylalkynyl adducts. 2-Chlorotrityl resin is highly suitable for the synthesis of peptide alcohols, e.g., peptaibols, and peptide ω-aminoalkylamides.

Supplier: Bachem Americas

Mating pheromone of mating type α cells of S. cerevisiae. This factor inhibits DNA synthesis, thereby preventing cell division of mating type a cells. The hydrophobic peptide binds to a class D G-protein-coupled receptor Ste2p.

Supplier: Spectrum Chemicals

Glycylglycine, Ultrapure, also known as Diglycine, is used in the synthesis of complex peptides. Ultrapure products supplied by Spectrum are indicative of a grade suitable for research purposes and typically are not suitable for human consumption or therapeutic use.

Supplier: Bachem Americas

Building block for the synthesis of precursor peptides for tritiation, and for use in "click chemistry".D-Pra-containing peptides can be modified or cyclized by 1,3-dipolar cycloaddition, e.g. with alkyl azides. Fmoc-D-Pra-OH can be used for obtaining aryl-modified D-Phe derivatives via rhodium-catalyzed [2+2+2]-cycloaddition.

Supplier: ALADDIN SCIENTIFIC

α,α′-Dichloro-o-xylene reacts with elemental tellurium and NaI in 2-methoxyethanol to form 1,1-diiodo-3,4-benzo-1-telluracyclopentane.α,α′-Dichloro-o-xylene was used in solid-phase synthesis of large combinatorial variations of fundamental peptide unit.

Supplier: Prosci

KAT2A, or GCN5, is a histone acetyltransferase (HAT) that functions primarily as a transcriptional activator. It also functions as a repressor of NF-kappa-B (see MIM 164011) by promoting ubiquitination of the NF-kappa-B subunit RELA (MIM 164014) in a HAT-independent manner (Mao et al., 2009 [PubMed 19339690]).

Supplier: MP Biomedicals

p-Nitrophenol is used as an indicator in 0.1% alcohol solutions. 4-Nitrophenol is used as a precursor to prepare phenetidine, acetophenetidine and pH indicator. Its carboxylate ester derivatives are involved as an active component for the construction of amide moieties in peptide synthesis.

Supplier: Bachem Americas

For sermorelin see H-3705.

Supplier: CHEM-IMPEX INTERNATIONAL, INC

Supplier: Bioss

C Peptide is part of the molecule of Proinsulin, that consists of three parts: C Peptide and two long strands of amino acids (called the alpha and beta chains) that later become linked together to form the insulin molecule. From every molecule of proinsulin, one molecule of insulin plus one molecule of C Peptide are produced. C peptide is released into the blood stream in equal amounts to insulin. A test of C peptide levels will show how much insulin the body is making. Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.

Supplier: Bioss

C Peptide is part of the molecule of Proinsulin, that consists of three parts: C Peptide and two long strands of amino acids (called the alpha and beta chains) that later become linked together to form the insulin molecule. From every molecule of proinsulin, one molecule of insulin plus one molecule of C Peptide are produced. C peptide is released into the blood stream in equal amounts to insulin. A test of C peptide levels will show how much insulin the body is making. Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.