1797 Results for: "lockout&amp"

Supplier: Novus Biologicals

The APRT Antibody from Novus Biologicals is a rabbit polyclonal antibody to APRT. This antibody reacts with human. The APRT Antibody has been validated for the following applications: Western Blot, Immunohistochemistry, Immunocytochemistry / Immunofluorescence, Immunohistochemistry-Paraffin.

Supplier: ACCUFORM MANUFACTURING, INC

Alert your employees to the hazards of working in confined spaces

Supplier: Cayman Chemical Company

2 2-cGAMP, Purity: >/=98%, Cas number: 1465774-27-9, Molecular Formula: C20H24N10O13P2, Molecular Weight: 674.4 g/mol, Synonyms: 2,2 -Cyclic GMP-AMP, Adenosine-Guanosine 2,2 -cyclic monophosphate, adenylyl-(2 ? 5 )-2 -guanylic acid, Size: 1mg

Supplier: Bioss

AMP/ATP-binding subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism. In response to reduction of intracellular ATP levels, AMPK activates energy-producing pathways and inhibits energy-consuming processes: inhibits protein, carbohydrate and lipid biosynthesis, as well as cell growth and proliferation. AMPK acts via direct phosphorylation of metabolic enzymes, and by longer-term effects via phosphorylation of transcription regulators. Also acts as a regulator of cellular polarity by remodeling the actin cytoskeleton; probably by indirectly activating myosin. Gamma non-catalytic subunit mediates binding to AMP, ADP and ATP, leading to activate or inhibit AMPK: AMP-binding results in allosteric activation of alpha catalytic subunit (PRKAA1 or PRKAA2) both by inducing phosphorylation and preventing dephosphorylation of catalytic subunits. ADP also stimulates phosphorylation, without stimulating already phosphorylated catalytic subunit. ATP promotes dephosphorylation of catalytic subunit, rendering the AMPK enzyme inactive.

Supplier: Bioss

AMP/ATP-binding subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism. In response to reduction of intracellular ATP levels, AMPK activates energy-producing pathways and inhibits energy-consuming processes: inhibits protein, carbohydrate and lipid biosynthesis, as well as cell growth and proliferation. AMPK acts via direct phosphorylation of metabolic enzymes, and by longer-term effects via phosphorylation of transcription regulators. Also acts as a regulator of cellular polarity by remodeling the actin cytoskeleton; probably by indirectly activating myosin. Gamma non-catalytic subunit mediates binding to AMP, ADP and ATP, leading to activate or inhibit AMPK: AMP-binding results in allosteric activation of alpha catalytic subunit (PRKAA1 or PRKAA2) both by inducing phosphorylation and preventing dephosphorylation of catalytic subunits. ADP also stimulates phosphorylation, without stimulating already phosphorylated catalytic subunit. ATP promotes dephosphorylation of catalytic subunit, rendering the AMPK enzyme inactive.

Supplier: Bioss

Adenylsuccinate lyase is involved in both de novo synthesis of purines and formation of adenosine monophosphate from inosine monophosphate. It catalyzes two reactions in AMP biosynthesis: the removal of a fumarate from succinylaminoimidazole carboxamide (SAICA) ribotide to give aminoimidazole carboxamide ribotide (AICA) and removal of fumarate from adenylosuccinate to give AMP. Adenylosuccinase deficiency results in succinylpurinemic autism, psychomotor retardation, and , in some cases, growth retardation associated with muscle wasting and epilepsy. Two transcript variants encoding different isoforms have been found for this gene.

Supplier: Bioss

Adenylsuccinate lyase is involved in both de novo synthesis of purines and formation of adenosine monophosphate from inosine monophosphate. It catalyzes two reactions in AMP biosynthesis: the removal of a fumarate from succinylaminoimidazole carboxamide (SAICA) ribotide to give aminoimidazole carboxamide ribotide (AICA) and removal of fumarate from adenylosuccinate to give AMP. Adenylosuccinase deficiency results in succinylpurinemic autism, psychomotor retardation, and , in some cases, growth retardation associated with muscle wasting and epilepsy. Two transcript variants encoding different isoforms have been found for this gene.

Supplier: Bioss

Adenylsuccinate lyase is involved in both de novo synthesis of purines and formation of adenosine monophosphate from inosine monophosphate. It catalyzes two reactions in AMP biosynthesis: the removal of a fumarate from succinylaminoimidazole carboxamide (SAICA) ribotide to give aminoimidazole carboxamide ribotide (AICA) and removal of fumarate from adenylosuccinate to give AMP. Adenylosuccinase deficiency results in succinylpurinemic autism, psychomotor retardation, and , in some cases, growth retardation associated with muscle wasting and epilepsy. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].

Supplier: Bioss

Adenylsuccinate lyase is involved in both de novo synthesis of purines and formation of adenosine monophosphate from inosine monophosphate. It catalyzes two reactions in AMP biosynthesis: the removal of a fumarate from succinylaminoimidazole carboxamide (SAICA) ribotide to give aminoimidazole carboxamide ribotide (AICA) and removal of fumarate from adenylosuccinate to give AMP. Adenylosuccinase deficiency results in succinylpurinemic autism, psychomotor retardation, and , in some cases, growth retardation associated with muscle wasting and epilepsy. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].

Supplier: Trajan Scientific and Medical

Stainless steel unions, tees and crosses come in a variety of tube sizes and configurations, such as straight through, reducing, tees, crosses and bulkheads

Supplier: TRESTON IAC LLC

Electrical channels may be mounted (1) top/rear of worksurface, (2) under shelf front or rear, or (3) top rear of shelf. Features Four (4) 15-amp, 60-Hz duplexes, circuit breaker and 8-feet cord, Eze Blue, Quick Ship

Supplier: Prosci

CREB3L2 Polyclonal Antibody, Host: Rabbit, Species Reactivity: Human, Mouse, Isotype: Ig, Immunogen: KLH conjugated synthetic peptide between 490-517 aa from C-terminal region, Synonyms: Cyclic AMP-responsive element-bin

Supplier: Anaspec Inc

A synthetic peptide substrate specific for AMP-activated protein kinase (AMPK).
Sequence:HMRSAMSGLHLVKRR-NH2
MW:1778.2 Da
% peak area by HPLC:95
Storage condition:-20° C

Supplier: Bioss

The protein encoded by this gene belongs to the ser/thr protein kinase family. It is the catalytic subunit of the 5'-prime-AMP-activated protein kinase (AMPK). AMPK is a cellular energy sensor conserved in all eukaryotic cells. The kinase activity of AMPK is activated by the stimuli that increase the cellular AMP/ATP ratio. AMPK regulates the activities of a number of key metabolic enzymes through phosphorylation. It protects cells from stresses that cause ATP depletion by switching off ATP-consuming biosynthetic pathways. Alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq].

Supplier: Ace Glass

Replacement fuses for Ace Glass instruments

Supplier: ACCUFORM MANUFACTURING, INC

Alert your employees to the hazards of working in confined spaces

Supplier: Alere

Rapid Drug Screen for the simultaneous, qualitative detection of single or multiple drug metabolites in human urine

Supplier: ACCUFORM MANUFACTURING, INC

Provides the flexibility to effectively lockout breaker switches

Supplier: Ace Glass

Motor and controller, motor is non-reversible, 1/12 hp DC, 5/16" dia shaft 1" long

Supplier: Brady Worldwide

A successful lockout program begins with the right devices stored in the right places

Supplier: Wards

Low voltage power supply that can be used as a battery eliminator.

Supplier: Brady Worldwide

A successful lockout program begins with the right devices stored in the right places

Supplier: HCL Label

HCL's lockout tagout label is made of a durable adhesive vinyl.

Supplier: Brady Worldwide

A successful lockout program begins with the right devices stored in the right places

Supplier: Anaspec Inc

AMARA peptide is a minimal substrate for several members of the protein kinases family. It contains the phosphorylation site for AMP-activated Protein Kinase (AMPK). AMARA peptide may be employed in the applications to measure AMPK-related kinase activity.
Sequence:AMARAASAAALARRR
MW:1542.8 Da
% peak area by HPLC:95
Storage condition:-20° C

Supplier: Promega Corporation

Recombinant full-length human AMPK (combination of A1/B1/G2 subunits) was expressed by baculovirus in Sf9 insect cells using a C-terminal His tag. AMP-activated protein kinase (AMPK) exhibits a key role as master regulator of cellular energy homeostasis.

Supplier: Bachem Americas

Specific substrate for the sucrose-non-fermenting protein kinase (SNF1) from Saccharomyces cerevisiae and its mammalian counterpart, AMP-activated protein kinase (AMPK).

Supplier: BioVendor

Gastrokine 1, previously known as AMP-18, CA11, FOVEOLIN and TFIZ, was formally named “GKN1” by the HUGO gene Nomenclature Committee for its gastric-specific expression and its highly conserved presence in the gastric mucosa of many mammalian species. Gastrokine 1 is a novel protein that was firstly cloned by a Japanese group in 2000. GKN1 belongs to a family of genes encoding stomach-specific secreted proteins consisting of 3 known members: gastrokine 1 (GKN1), gastrokine 2 (GKN2) and gastrokine 3 (GKN3). GKN1 gene of about 6 kb was reported to be located at 2p13 and contains 6 exons. The GKN1 gene encodes a small protein of 185 amino acids containing a N-terminal signal peptide. It is a secreted protein with a molecular weight of approximately 18 kDa. GKN1 protein contains a BRICHOS domain, which is associated with dementia, respiratory distress and cancer.

Supplier: Rockland Immunochemical

ATF6, Polyclonal antibody, Host: Rabbit, Species: Human, Isotype: IgG, Immunogen: shows 100% identity with human and 80% identity to rat, Synonyms: Cyclic AMP-dependent transcription factor ATF-6 alpha, Activating transcription factor 6 alpha, ATF6 a, Size: 25 uL

Supplier: Alere

Rapid Drug Screen for the simultaneous, qualitative detection of single or multiple drug metabolites in human urine