Supplier: Avantor Fluid Handling

Versatile gear pump drives for high-accuracy, pulseless fluid delivery – with an intuitive touch-screen interface.

Supplier: Genetex

Jun activation domain-binding protein 1 (JAB1) also designated COP9 subunit 5 (COPS5) or SGN5 is a coactivator of AP1 transcription factor that also promotes degradation of the cyclin-dependent kinase inhibitor p27Kip1. JAB1 interacts with c-Jun AP1 containing complexes, and enhances transactivation from AP1 dependent promoters. It also interacts with Jun D but not with Jun B or v-Jun. JAB1 is highly conserved in evolution and is widely expressed in mammalian tissues. It is localized both the nucleus and the cytoplasm. It interacts with the cytoplasmic domain of the alphaL/beta2 integrin LFA1. Following LFA1 engagement the nuclear pool of JAB1 increases and activation of an AP1 driven promoter is enhanced. Interaction of JAB1 with the nuclear progesterone receptor and the steroid receptor activator (SRC1) was reported. JAB1 is a stability and activity regulator of Hypoxia - inducible factor 1 (HIF1), a transcription factor that controls activation of several genes responsive to the cellular oxygen tension. The macrophage migration inhibitory factor (MIF) associates with JAB1 in the cytosol near the plasma membrane. Endogenous MIF inhibits JAB1-induced AP1 transcriptional activity. JAB1 is a subunit of the COP9 regulatory complex. COP9 cleaves the ubiquitin-like protein Nedd8 from the Cul1 subunit of SCF ubiquitin ligases. A metalloprotease motif in JAB1 plays a role in this isopeptidase activity. Breakdown of the cyclin dependent kinase inhibitor p27Kip1 is promoted by JAB1. The latter expression in several cancers inversely correlates with p27Kip1 and may reflect tumor aggressiveness. A possible involvement of JAB1 in atherosclerosis was also reported. Involvement of JAB1 in degradation of the suppressors p53 and smad4 was described recently.

Supplier: Vileda Professional - FHP

The less time spent on cleanroom cleaning, the less interference with keeping the core business running. The unique CE Duo Mop concept is the perfect answer for the high demands of effective cleaning and disinfection of cleanrooms and controlled environments. It is faster, easier, and twice as efficient as traditional methods. The CE Duo Mops allow users to achieve contact time requirements for common disinfectants, and still reach an excellent cleaning performance, with up to 99.99% bacteria removal. The CleanTech™ and SanTech™ Duo Mops form the most efficient and reliable cleaning concept in the market for contamination control.

Supplier: Analytik Jena US

The UVP ChemStudio Systems offer 2 different camera options and an upgradable platform for NIR imaging. The extensive analytical software and range of epi LEDs included with the system ensure every application need is met.

Supplier: Labconco

CentriVap Pro Benchtop vacuum concentrators are designed to rapidly concentrate multiple small samples using centrifugal force, vacuum and heat. A touch screen interface and integrated software allow for real-time control and display of run parameters, data collection and storage, program development, and diagnostics. As many as 312 samples may be processed at once when utilizing double-stacked rotor arrangement. Sample sizes range from a few microliters up to 50 ml.

Supplier: DWK Life Sciences (KIMBLE)

The Acura^® electro pipettes are the latest upgrade of a successful line that makes electronic pipetting more versatile, simpler, and safer than ever.

Supplier: Memmert

Memmert stability chambers are constructed of stainless steel inside and out. The ICH L stability chamber will save energy and perform well for any project.

Supplier: VWR International

The VWR® Advanced 3500 Orbital Shaker is designed for a wide range of applications including cell cultures that require accurate and repeatable results. The microprocessor control provides consistent uniform shaking while safely ramping the set speed.

Supplier: Sartorius

Sartorius optifit pipette tips are an excellent choice for various laboratories and pipetting tasks with their wide range of packaging and purity options. These tips are non-filtered and designed for best possible fitting and sealing on Sartorius pipettes to secure the highest possible accuracy, precision, and reproducibility.

Supplier: Thermo Fisher Scientific

Stackable orbital shakers provide an ideal solution for both sensitive cultures and traditional 'hard shake' applications in incubated and refrigerated configurations.

Supplier: SenseAnywhere

The SenseAnywhere Temp+rh Module offers precise temperature and humidity monitoring from −40 to +70 °C and 0 to 99% rh (non-condensing) with swift response time.

Supplier: MilliporeSigma

L-Arginine hydrochloride 98.5-101.0% (by perchloric acid titration), EMPROVE® EXPERT Ph. Eur., BP, JP, USP suitable for use as excipient, SAFC®

Supplier: Corning

Corning® Synthegel™ 3D matrices are chemically defined peptides that self assemble into nanofibers which crosslink to form tuneable hydrogels. These hydrogels provide a robust and reproducible microenvironment for 3D culture of physiological spheroids and hiPS cells. The Synthegel™ matrix kits provide negligible variability and a more controlled substrate for in vivo-like 3D cell culture. Such a platform is needed for cancer research, stem cell research, and drug screening in a 3D format.

Supplier: INTACT GENOMICS, INC MS

Intact Genomics chemically competent Agrobacterium combo pack is perfect for scientists who require multiple Agrobacterium competent cell strains for their research. The chemically competent Agrobacterium combo pack contains three 50 µl aliquots of GV3101, AGL1, EHA105 and LBA4404 along with pCambia and our proprietary Agro Recovery Media.

Supplier: Globe Scientific

Globe Glass™ volumetric flasks are calibrated to meet ASTM tolerance specifications for precise measurement in solution preparation and dilution. A diamond etched graduation line indicates the calibrated capacity of each measuring flask. Wide mouth options are available for easier filling and mixing. Globe Glass™ volumetric flasks are offered in sizes ranging from 1 to 2000 ml, and with Class A or Class B calibration tolerances. Class A volumetric flasks include a batch calibration certificate.

Supplier: ReVacc Scientific

This pseudotyped virus uses recombinant vesicular stomatitis virus (rVSV) to carry the S protein of SARS-CoV-2 (GenBank: MN908947) with multiple mutations initially identified in variant of Omicron BF.7. The S has 18-aa cytoplasmic tail truncation for optimal infection.

Supplier: Eppendorf

The refrigerated Eppendorf Centrifuge 5920 R offers high-throughput performance and advanced temperature management in a very compact design. With a capacity of up to 4×1000 ml/52×50 ml conical tubes, it can spin both plates and tubes in the same bucket for real flexibility.

Supplier: BioVendor

Of all the CTRP paralogs, CTRP9 shows the highest degree of amino acid identity to adiponectin in its globular C1q domain.

Supplier: SenseAnywhere

The SenseAnywhere temp only module offers precise temperature monitoring from −40 to +70 °C with swift response time, ideal for dynamic environments and hard-to-reach spaces. Compatible with the AiroSensor 20-20-43, it meets top accuracy standards and can extend its range with SAB extension cables.

Supplier: YSI

Rugged and reliable, the YSI Pro1020 provides everything you need in a handheld instrument for the measurement of either pH or ORP along with temperature, and dissolved oxygen.

Supplier: Cytiva

Blue Sepharose™ 6 Fast Flow is cibacron blue 3G coupled to Sepharose™ 6 Fast Flow. It is well established as an adsorbent for albumin and interferon at both laboratory and process scale. The blue dye binds many proteins, such as albumin, interferon, lipoproteins and blood coagulation factors. It also binds several enzymes including kinases, dehydrogenases, and most enzymes requiring adenyl-containing cofactors e.g. NAD+.

Supplier: Agilent Technologies

BL21 competent cells are an all-purpose strain for high-level protein expression and easy induction.

Supplier: Nidec Shimpo America

FG-7000 Series Data logging, Digital Force Gauge, Loaded with functionality to simplify compression and tension testing needs. Menu programming for easy selection and set-up of the instrument to desired requirements with three unique modes of operation.

Supplier: Molecular Devices

Overcome the challenges associated with conventional cell confluence techniques with the CloneSelect Imager system - producing objective, quantitative, and consistent results in less time.

Supplier: 3M Healthcare

Zeta Plus™ SP Series Filter Cartridges to provide optimal clarification of pharmaceutical, biological, bioprocess and cosmetic fluids. They are constructed with Zeta Plus™ SP Series depth filtration media, composed of inorganic filter aid, cellulose and a resin system that imparts a positive charge to the filter matrix, aiding its adsorption of negatively charged contaminants.

Supplier: NABERTHERM INC.

Due to their maximum temperature of 1650 °C and their large chamber, these high-temperature bottom loading furnaces are perfectly suited for sintering translucent zirconia. The motor-driven lifting table significantly simplifies the charging of the high-temperature furnace. The all-around heating of the cylindrical furnace chamber ensures a very even temperature uniformity.

Supplier: Nidec Shimpo America

FG-3000 Series Data logging, Compact Digital Force Gauge, Loaded with functionality to simplify compression and tension testing needs. Menu programming for easy selection and set-up of the instrument to desired requirements with three unique modes of operation.

Supplier: Upchurch Scientific

It is good practice to filter solvents to prevent pump and other system component damage.

Supplier: Labconco

Refrigerated CentriVap™ Pro Vacuum Concentrators are designed to rapidly concentrate heat-sensitive samples, such as RNA and proteins, using centrifugal force, vacuum and controlled temperature. This concentrator combines a refrigeration system that cools to –10 °C with a heater that warms to 100 °C to achieve the user’s desired set point temperatures. As many as 296 sample containers may be processed at once when utilizing double-stacked rotor arrangement. Sample sizes range from a few microliters up to 50 ml.

Supplier: Avantor Fluid Handling

Versatile piston pump drives for high-accuracy fluid dispensing and delivery – with an intuitive touch-screen interface.