"TEMPO BIOSCIENCE, INC"

Supplier: TEMPO BIOSCIENCE, INC

Human iPSC-derived Astrocytes (type 1 or II).

Supplier: TEMPO BIOSCIENCE, INC

Human iPSC-derived CD14+ Monocytes.

Supplier: TEMPO BIOSCIENCE, INC

TempoMito biosensor transiently expressed in U2OS

Supplier: TEMPO BIOSCIENCE, INC

Human iPSC-derived Neural Progenitor Cells.

Supplier: TEMPO BIOSCIENCE, INC

Human iPSC-derived Kidney Proximal Tubules and Podocyte 3D Spheroids.

Supplier: TEMPO BIOSCIENCE, INC

Human iPSC-derived Melanocytes.

Supplier: TEMPO BIOSCIENCE, INC

Hepatic stellate cells are responsible for the regulation of extracellular matrix proteins and vascular structure in the liver. They represent approximately 5 to 8% of the cells in the liver and function to maintain homeostasis in the microenvironment of the hepatic sinusoid. They play a critical role in the development of liver fibrosis. When chronic liver damage occurs, hepatic stellate cells are actively synthesizing extracellular matrix proteins such as collagen and other glycoproteins. The accumulation of the extracellular matrix proteins trigger hepatic fibrosis which can lead to cirrhosis.

Supplier: TEMPO BIOSCIENCE, INC

TempoATP biosensor transiently expressed in TempoRapid neuroepithelial cells.

Supplier: TEMPO BIOSCIENCE, INC

TempoVol biosensor transiently expressed in TempoRapid neuroepithelial cells

Supplier: TEMPO BIOSCIENCE, INC

TempoMito biosensor transiently expressed in TempoRapid neuroepithelial cells

Supplier: TEMPO BIOSCIENCE, INC

Calcium Biosensor Assay using Human Astrocytes.

Supplier: TEMPO BIOSCIENCE, INC

TempoMito biosensor transiently expressed in HEK293t

Supplier: TEMPO BIOSCIENCE, INC

Human iPSC-derived Cortical Neurons.

Supplier: TEMPO BIOSCIENCE, INC

TempoCal biosensor transiently expressed in TempoRapid neuroepithelial cells

Supplier: TEMPO BIOSCIENCE, INC

Human iPSC-derived Cardiomyocytes.

Supplier: TEMPO BIOSCIENCE, INC

Liver sinusoidal endothelial cells (LSECs) are the most abundant non-parenchymal hepatic cell population. They are highly specialized liver endothelial cells that form a barrier to separate hepatocytes and hepatic stellate cells from contacting the blood. In additional to serving as a physical barrier, LSECs have critical physiological and immunological functions. Furthermore, LSECs regulate cell-to-cell crosstalk as chronic liver conditions advance, eventually leading to fibrosis and carcinogenesis.