"Stemcell Technologies"

Supplier: Stemcell Technologies

Mouse monoclonal IgG1 antibody against human, rhesus, sooty mangabey CD123 (IL-3Rα), PE-conjugated.

Supplier: Stemcell Technologies

Interferon-alpha (IFN-α) is a type I interferon, produced by virus infected cells, and is released as a soluble factor to initiate antiviral responses (Isaacs and Lindenmann). IFN-α2 is the most potent IFN-α used in fundamental research and in most clinical applications. The best known IFN-α2 subvariants, 2A and 2B, differ by only one or two amino acids at positions 23 and/or 34 of the mature protein (von Gabain et al.). Type I IFNs exert potent antitumor activity by increasing the cytotoxic activity of NK and T cells, as well as inhibiting the proliferation of cancer cells (Paul et al.). Additionally, it has been shown that proinflammatory IFN-α modulates the function of B cells in patients with systemic lupus erythematosus (Chang et al.) and pegylated form of IFN-α 2A and 2B has implications in the treatment of Hepatitis C (Foster et al.).

Supplier: Stemcell Technologies

Complete kit including collagen, media, staining kit and chamber slide kit for human CFU-Mk assays.

Supplier: Stemcell Technologies

Mouse monoclonal IgG3, kappa isotype control antibody, unconjugated.

Supplier: Stemcell Technologies

Supplement for the expansion and differentiation of lymphoid progenitor cells.

Supplier: Stemcell Technologies

Rat (WI) monoclonal IgG2b antibody against mouse TER119.

Supplier: Stemcell Technologies

Cas9 nuclease (4 μg/μl) for the generation of double-strand breaks in CRISPR-Cas9 genome editing.

Supplier: Stemcell Technologies

Mouse monoclonal IgG1 antibody against human CD326 (EpCAM), unconjugated.

Supplier: Stemcell Technologies

Immunomagnetic isolation of mouse CD4+CD25+ regulatory T cells.

Supplier: Stemcell Technologies

Mouse monoclonal IgG1, antibody against human, chimpanzee CD4, PE-conjugated.

Supplier: Stemcell Technologies

cGMP, enzyme-free cell dissociation reagent.

Supplier: Stemcell Technologies

Stromal cell-derived factor 1 alpha (SDF-1α) is a member of the CXC group of chemokines that binds to the G-protein coupled receptor, CXCR4, to regulate migration, proliferation, differentiation, and survival of many cell types including hematopoietic stem cells, B cells, and T cells. It is produced by bone marrow stromal cells, osteoblasts, endothelial cells, and neuronal cells. SDF-1α was first identified as the pre-B-cell growth-stimulating factor (PBSF) in the mouse bone marrow-derived stromal cell line, PA6, in the growth of B cell precursors (Hayashi et al.). SDF-1α primarily regulates cell motility during development and adulthood, including the homing of hematopoietic stem cells and neutrophils to fetal bone marrow during ontogeny (Ara et al. 2003a) and the recruitment of endothelial progenitor cells from bone marrow during angiogenesis in adulthood (Zheng et al.). In addition to its role in hematopoiesis, the SDF-1α/CXCR4 signaling pathway is also essential for the homing of primordial germ cells to gonads (Ara et al. 2003b), the migration of granule cells in the cerebellum during neurogenesis (Zou et al.), and the migration of breast cancer cells to sites of metastasis (Muller et al.).

Supplier: Stemcell Technologies

Mouse monoclonal IgM antibody against human, rat, rhesus TRA-1-81, unconjugated.

Supplier: Stemcell Technologies

Mouse monoclonal IgG2a, antibody against human CD3, unconjugated.

Supplier: Stemcell Technologies

Column-free immunomagnetic positive selection of human CD33+ and CD66b+ cells for HLA analysis.

Supplier: Stemcell Technologies

The EasySep™ magnet is designed for cell separation procedures using EasySep™ reagents.