"Stemcell Technologies"

Supplier: Stemcell Technologies

Supplement for expansion of mouse and rat neural stem and progenitor cells.

Supplier: Stemcell Technologies

Mouse monoclonal IgG1 antibody against human, rhesus, cynomolgus CD83, PE-conjugated.

Supplier: Stemcell Technologies

Purified tropoelastin, human, lyophilized, for tissue engineering research and cell culture - 1 mg

Supplier: Stemcell Technologies

For the in vitro differentiation of human MSCs into osteoblasts.

Supplier: Stemcell Technologies

Mouse monoclonal IgG2b antibody against human, rhesus HLA-DR, FITC-conjugated.

Supplier: Stemcell Technologies

The EasySep™ 'The Big Easy' magnet is designed for cell separation procedures using EasySep™ reagents when processing a large number of cells, or when using RoboSep™.

Supplier: Stemcell Technologies

For depletion of red blood cells from fresh blood samples and isolation of nucleated cells.

Supplier: Stemcell Technologies

Mouse monoclonal IgG1 antibody against human CD326 (EpCAM), FITC-conjugated.

Supplier: Stemcell Technologies

Rat monoclonal IgG2b antibody against mouse CD16/CD32, unconjugated.

Supplier: Stemcell Technologies

Immunomagnetic isolation of untouched human CD4+ T cells.

Supplier: Stemcell Technologies

For neural differentiation of mouse and human ES and iPS cells.

Supplier: Stemcell Technologies

For digestion of native collagen fibrils.

Supplier: Stemcell Technologies

Measure and transfer liquids precisely and safely using Corning® Lambda™ Plus multi-channel pipettors.

Supplier: Stemcell Technologies

Interleukin 2 (IL-2) is a monomeric cytokine that was originally identified as a T cell growth factor (Gaffen and Liu). It binds to heterotrimeric receptors consisting of CD25, CD122, and CD132. Upon binding, it activates JAK3-, STAT5-, and AKT-dependent signaling pathways, which results in cellular proliferation and survival (Ma et al.). The majority of IL-2 is secreted by activated CD4+ and CD8+ T cells, although B cells and dendritic cells were found to produce IL-2 in small amounts. IL-2 downregulates immune responses to prevent autoimmunity during thymic development, influences the development of CD4+CD25+ regulatory T cells, and affects development of follicular helper T cells. IL-2 also controls inflammation by inhibiting Th17 differentiation (Banchereau et al.). High IL-2 levels in serum are associated with progression of scleroderma, rheumatoid arthritis, and gastric and non-small cell lung cancer, though no known disease can be directly attributed to the lack or excess of IL-2 (Gaffen and Liu).

Supplier: Stemcell Technologies

Immunomagnetic positive selection of human CD14+ cells (e.g. monocytes).

Supplier: Stemcell Technologies

Nerve growth factor (NGF)-beta is a prototypical member of the neurotrophin family and has a role in the survival and growth of neural cells, regulating cell growth, promoting differentiation into neurons, and neuron migration. The beta subtype of NGF is biologically active in comparison to the alpha-2 and gamma-2 subtypes. NGF-beta in its secreted form can bind to tyrosine kinase A (TrkA) receptor with high affinity and to p75 (NTR) with low affinity (Levi and Alemà; Sofroniew et al.). NGF has been shown to possess pro-inflammatory and pro-fibrogenic properties (Micera et al.). It has also been shown that overexpression of NGF-beta promotes differentiation of bone marrow mesenchymal stem cells into neurons through regulation of AKT and MAPK pathways (Yuan et al.).