46 Results for: "STILLA TECHNOLOGIES, INC."

Supplier: STILLA TECHNOLOGIES, INC.

The EGFR 6-color crystal digital PCR® kit allows for the detection and quantification of up to 32 somatic EGFR mutations in exons 18, 19, 20, and 21 associated with non-small cell lung cancer (NSCLC).

Supplier: STILLA TECHNOLOGIES, INC.

Assay-specific crystal flex probes and primers for the detection of ESRI mutations and its positive control. ESR1 (11 mutations) Crystal Digital PCR® assay is a 10X assay designed to detect and quantify 11 mutations in the ESR1 gene using the ruby chip. ESR1 is pivotal in mediating resistance to endocrine therapy in metastatic hormone-positive breast cancer.

Supplier: STILLA TECHNOLOGIES, INC.

Assay-specific Crystal Flex Probes and primers for the detection of NRAS mutations and its positive control. NRAS (G12D, drop-off G12-G13) Crystal Digital PCR® Assay is a 10X assay designed to detect and quantify mutations in G12-G13 plus 1 mutation of the NRAS gene using the Ruby Chip. NRAS is pivotal in regulating cell signaling pathways implicated in cancer development, notably melanoma and colorectal cancer.

Supplier: STILLA TECHNOLOGIES, INC.

Assay-specific Crystal Flex Probes and primers for the detection of HPV genotypes and its Positive Control. HPV (ALB, HPV16/18/31/33/35/39/45/51/52/56/58) Crystal Digital PCR® Assay is a 10X assay designed to detect and quantify 11 high risk HPV genotypes for cervical cancer plus a reference gene for human DNA quantification using the Ruby Chip.

Supplier: STILLA TECHNOLOGIES, INC.

Assay-specific Crystal Flex Probes and primers for the detection of BRCA1 Methylation and its Positive Control. The BRCA1 Methylation Crystal Digital PCR® Assay is a 10X assay designed to detect and quantify methylation of the BRCA1 promoter using the Ruby Chip. BRCA1 is crucial for maintaining genomic stability by repairing DNA damage, regulating the cell cycle, and acting as a tumor suppressor to prevent cancer.

Supplier: STILLA TECHNOLOGIES, INC.

Crystal universal reporters generate fluorescent signals when activated during a Crystal Digital PCR® reaction using target-specific crystal flex probe detection chemistry.

Supplier: STILLA TECHNOLOGIES, INC.

Assay-specific crystal flex probes and primers for the detection of KRAS mutations and its positive control. The KRAS (G12C, drop-off G12-G13) Crystal Digital PCR® assay is a 10X assay designed to detect and quantify mutations in codons 12 and 13 plus one mutation of the KRAS gene. KRAS is pivotal in regulating cell signaling pathways implicated in cancer development, notably melanoma and colorectal cancer.

Supplier: STILLA TECHNOLOGIES, INC.

Assay-specific crystal flex probes and primers for the detection of KRAS mutations and its positive control. The KRAS (G12, G12C) Crystal Digital PCR® assay is a 10X assay designed to detect and quantify one mutation in the KRAS gene using the ruby chip. KRAS is pivotal in regulating cell signaling pathways implicated in cancer development, notably melanoma and colorectal cancer.

Supplier: STILLA TECHNOLOGIES, INC.

Assay-specific Crystal Flex Probes and primers for the detection of EGFR mutations and its Positive Control. The EGFR (drop-off Del19) Crystal Digital PCR® Assay is a 10X assay designed to detect and quantify EGFR Exon 19 deletion mutations using the Ruby Chip. EGFR encodes for the epidermal growth factor receptor, a protein that plays a crucial role in cell growth, proliferation, and differentiation.

Supplier: STILLA TECHNOLOGIES, INC.

Assay-specific Crystal Flex Probes and primers for the detection of NRAS mutations and its positive control.The NRAS (drop-off Q61) Crystal Digital PCR® Assay is a 10X assay designed to detect and quantify mutations in Q61 of the NRAS gene using the Ruby Chip. NRAS is pivotal in regulating cell signaling pathways implicated in cancer development, notably melanoma and colorectal cancer.

Supplier: STILLA TECHNOLOGIES, INC.

Assay-specific crystal flex probes and primers for the detection of BRAF/KRAS/NRAS mutations and its positive control. The BRAF/KRAS/NRAS Crystal Digital PCR® assay is a 10X assay designed to detect and quantify mutations in BRAF, KRAS, and NRAS genes using the ruby chip. BRAF, KRAS, and NRAS genes are pivotal in regulating cell signaling pathways implicated in cancer development.

Supplier: STILLA TECHNOLOGIES, INC.

Assay-specific Crystal Flex Probes and primers for the detection of NRAS mutations and its positive control. NRAS (Q61K, drop-off Q61) Crystal Digital PCR® Assay is a 10X assay designed to detect and quantify mutations in Q61 plus 1 mutation of the NRAS gene. NRAS is pivotal in regulating cell signaling pathways implicated in cancer development, notably melanoma and colorectal cancer.

Supplier: STILLA TECHNOLOGIES, INC.

Routine Operational Qualification (OQ) procedures of the naica® system and Nio™+ can be performed using the naica® IQ/OQ Kit.

Supplier: STILLA TECHNOLOGIES, INC.

The naica® mutliplex PCR MIX is a ready-to-use two-component solution specifically formulated for optimal TaqMan® fluorescent probe-based Crystal Digital PCR®.

Supplier: STILLA TECHNOLOGIES, INC.

Assay-specific Crystal Flex Probes and primers for the detection of BRAF mutations and its Positive Control. BRAF (V600, V600E) Crystal Digital PCR® Assay is a 10X assay designed to detect and quantify 1 mutation in the BRAF gene using the Ruby Chip. BRAF is pivotal in regulating cell signaling pathways implicated in cancer development, notably melanoma, colorectal cancer and thyroid cancer, through its role in the MAPK/ERK pathway. Mutations in BRAF, particularly the V600E mutation, lead to uncontrolled cell proliferation and survival.

Supplier: STILLA TECHNOLOGIES, INC.

Assay-specific crystal flex probes and primers for the detection of NRAS mutations and its positive control. The NRAS (drop-off G12-G13) Crystal Digital PCR® assay is a 10X assay designed to detect and quantify mutations in codons 12 and 13 of the NRAS gene using the ruby chip. NRAS is pivotal in regulating cell signaling pathways implicated in cancer development, notably melanoma and colorectal cancer.

Supplier: STILLA TECHNOLOGIES, INC.

Assay-specific Crystal Flex Probes and primers for the detection of TP53 mutations and its positive control. TP53 (drop-off V272-A276/R283-E286) Crystal Digital PCR® Assay is a 10X assay designed to detect and quantify mutations between V272-A276 or R283-E286 of the TP53 gene using the Ruby Chip. TP53 is pivotal in regulating cell divisison, thus an important tumor suppressor gene.

Supplier: STILLA TECHNOLOGIES, INC.

Assay-specific Crystal Flex Probes and primers for the detection of BRAF mutations and its Positive Control. BRAF (V600, V600E, V600K) Crystal Digital PCR® Assay is a 10X assay designed to detect and quantify 2 mutations in the BRAF gene using the Ruby Chip. BRAF is pivotal in regulating cell signaling pathways implicated in cancer development, notably melanoma, colorectal cancer and thyroid cancer, through its role in the MAPK/ERK pathway. Mutations in BRAF, particularly the V600E mutation, lead to uncontrolled cell proliferation and survival.

Supplier: STILLA TECHNOLOGIES, INC.

Assay-specific Crystal Flex Probes and primers for the detection of NRAS mutations and its Positive Control. NRAS (Q61, Q61R, Q61K) Crystal Digital PCR® Assay is a 10X assay designed to detect and quantify 2 mutations in the NRAS gene using the Ruby Chip. NRAS is pivotal in regulating cell signaling pathways implicated in cancer development, notably melanoma and colorectal cancer.

Supplier: STILLA TECHNOLOGIES, INC.

Assay-specific Crystal Flex Probes and primers for the detection of TP53 mutations and its Positive Control. TP53 (drop-off V272-A276/G280-R283) Crystal Digital PCR® Assay is a 10X assay designed to detect and quantify mutations between V272-A276 or G280-R283 of the TP53 gene using the Ruby Chip. TP53 is pivotal in regulating cell divisison, thus an important tumor suppressor gene.

Supplier: STILLA TECHNOLOGIES, INC.

Assay-specific crystal flex probes and primers for the detection of KRAS mutations and its positive control. The KRAS (G12A, G12C, G12D, G12V, drop-off G12-G13) Crystal Digital PCR® assay is a 10X assay designed to detect and quantify mutations in codons 12 and 13 plus 4 mutations in the KRAS gene using the ruby chip. KRAS is pivotal in regulating cell signaling pathways implicated in cancer development, notably melanoma and colorectal cancer.

Supplier: STILLA TECHNOLOGIES, INC.

Assay-specific crystal flex probes and primers for the detection of BRCA1/RAD51C/GSTP1 methylation and its positive control. The BRCA1/RAD51C/GSTP1 methylation Crystal Digital PCR® assay is a 10X assay designed to detect and quantify methylation of the BRCA1, RAD51C, and GSTP1 promoter using the ruby chip. Methylation of the BRCA1, RAD51C, and GSTP1 affects DNA repair mechanisms crucial for genome stability and dysregulation of detoxification pathways, both contributing to tumor initiation, progression, and drug resistance.

Supplier: STILLA TECHNOLOGIES, INC.

Assay-specific crystal flex probes and primers for the detection of RAD51C Methylation and its positive control. The RAD51C methylation Crystal Digital PCR® assay is a 10X assay designed to detect and quantify methylation of the RAD51C promoter using the ruby chip. RAD51C gene is involved in DNA repair, particularly in the homologous recombination pathway for genome stability.

Supplier: STILLA TECHNOLOGIES, INC.

Assay-specific Crystal Flex Probes and primers for the detection of NRAS mutations and its Positive Control. NRAS (Q61, Q61K) Crystal Digital PCR® Assay is a 10X assay designed to detect and quantify 1 mutation in the NRAS gene using the Ruby Chip. NRAS is pivotal in regulating cell signaling pathways implicated in cancer development, notably melanoma and colorectal cancer.

Supplier: STILLA TECHNOLOGIES, INC.

Assay-specific crystal flex probes and primers for the detection of c-KIT mutations and its positive control. The c-KIT (D816, D816V) Crystal Digital PCR® Assay is a 10X assay designed to detect and quantify 1 mutation in the c-KIT gene using the Ruby Chip. c-KIT encodes for a receptor tyrosine kinase that plays a crucial role in cell signaling for processes including cell survival, proliferation, and differentiation.

Supplier: STILLA TECHNOLOGIES, INC.

The naica® PCR MIX is a ready-to-use two-component solution optimized for EvaGreen® fluorescent intercalating dye-based Crystal Digital PCR®.

Supplier: STILLA TECHNOLOGIES, INC.

Assay-specific Crystal Flex Probes and primers for the detection of EGFR mutations and its Positive Control. The EGFR (L858, L858R, L861Q) Crystal Digital PCR® Assay is a 10X assay designed to detect and quantify 2 mutations in the EGFR gene using the Ruby Chip. EGFR encodes for the epidermal growth factor receptor, a protein that plays a crucial role in cell growth, proliferation, and differentiation.

Supplier: STILLA TECHNOLOGIES, INC.

Assay-specific Crystal Flex Probes and primers for the detection of C. albicans and its Positive Control. C. albicans Crystal Digital PCR® Assay is a 10X assay designed to detect and quantify 16 genes (1 gene per chromosome) of Candida albicans using the Ruby Chip. Candida albicans is a common yeast within the human gastrointestinal microbiota. Under certain conditions, it can become pathogenic leading to infections.

Supplier: STILLA TECHNOLOGIES, INC.

Assay-specific Crystal Flex Probes and primers for the detection of MYD88 mutations and its positive control. The MYD88 (L265, L265P) Crystal Digital PCR® Assay is a 10X assay designed to detect and quantify 1 mutation in the MYD88 gene using the Ruby Chip. MYD88 encodes the MYD88 protein, which is an adaptor protein essential for transmitting signals in the immune system, mediating responses to infections, and modulating inflammation and cell survival.

Supplier: STILLA TECHNOLOGIES, INC.

Assay-specific crystal flex probes and primers for the detection of GSTP1 methylation and its positive control. The GSTP1 methylation Crystal Digital PCR® assay is a 10X assay designed to detect and quantify methylation of the GSTP1 promoter using the ruby chip. The GSTP1 promoter is implicated on the GSTP1 epigenetic silencing and dysregulation of detoxification pathways contributing to tumor initiation, progression, and drug resistance.