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29853 results for "Reagents"

29853 Results for: "Reagents"

Neomycin sulfate ≥600 µg/mg USP

Supplier: MP Biomedicals

This product acts by binding to the 30S and 50S subunits, causing miscoding and inhibiting initiation and elongation during protein synthesis.

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Sulfo-LC-SPDP (Sulfosuccinimidyl 6-(3'-(2-pyridyldithio)propionamido)hexanoate) ≥90%, Pierce™

Sulfo-LC-SPDP (Sulfosuccinimidyl 6-(3'-(2-pyridyldithio)propionamido)hexanoate) ≥90%, Pierce™

Supplier: Invitrogen

Thermo Scientific Pierce Sulfo-LC-SPDP is a water-soluble, long-chain crosslinker for amine-to-sulfhydryl conjugation via NHS-ester and pyridyldithiol reactive groups that form cleavable (reducible) disulfide bonds with cysteines.

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Anti-CD28 Mouse Monoclonal Antibody (PE (Phycoerythrin)) [clone: CD28.2]

Anti-CD28 Mouse Monoclonal Antibody (PE (Phycoerythrin)) [clone: CD28.2]

Supplier: Tonbo Biosciences

The CD28.2 antibody reacts with human CD28, a 44 kDa type I surface glycoprotein which acts as a co-stimulatory receptor in support of the T cell receptor (TCR). CD28 exists as a homodimer with specificity for two known ligands, known as B7-1 (CD80) and B7-2 (CD86), which are expressed on activated B cells and antigen-presenting cells. These ligands trigger CD28 signaling in concert with TCR activation to drive T cell proliferation, induce high-level expression of IL-2, impart resistance to apoptosis, and enhance T cell cytotoxicity. The interaction / co-stimulatory signaling between the B7 ligands and CD28 provides crucial communication between T cells and B cells or APCs to coordinate the adaptive immune response. Other members of the CD28 family of receptors include CTLA-4 (CD152), PD-1 (CD279), ICOS and BTLA.

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Anti-CD28 Mouse Monoclonal Antibody (APC (Allophycocyanin)) [clone: CD28.2]

Anti-CD28 Mouse Monoclonal Antibody (APC (Allophycocyanin)) [clone: CD28.2]

Supplier: Tonbo Biosciences

The CD28.2 antibody reacts with human CD28, a 44 kDa type I surface glycoprotein which acts as a co-stimulatory receptor in support of the T cell receptor (TCR). CD28 exists as a homodimer with specificity for two known ligands, known as B7-1 (CD80) and B7-2 (CD86), which are expressed on activated B cells and antigen-presenting cells. These ligands trigger CD28 signaling in concert with TCR activation to drive T cell proliferation, induce high-level expression of IL-2, impart resistance to apoptosis, and enhance T cell cytotoxicity. The interaction / co-stimulatory signaling between the B7 ligands and CD28 provides crucial communication between T cells and B cells or APCs to coordinate the adaptive immune response. Other members of the CD28 family of receptors include CTLA-4 (CD152), PD-1 (CD279), ICOS and BTLA.

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PIPES monosodium salt ≥99.0% (by titrimetric analysis)

Supplier: TCI America

[Good's buffer component for biological research]
CAS Number: 10010-67-0
MDL Number: MFCD00065472
Molecular Formula: C8H18N2O6S2
Molecular Weight: 324.34
Purity/Analysis Method: >99.0% (T)
Form: Crystal
Color: White

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Cell Systems Human Large Intestine Microvascular Endothelial Cells, Primary Cell and Media Company

Cell Systems Human Large Intestine Microvascular Endothelial Cells, Primary Cell and Media Company

Supplier: Cell Systems

Our primary human cells offer unmatched consistency and a more biologically relevant tool than other cell types. Our cells are antibody-free and come from a deep inventory to help researchers with reproducibility and improved human insights.

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Cell Systems Human Synovial Microvascular Endothelial Cells, Primary Cell and Media Company

Cell Systems Human Synovial Microvascular Endothelial Cells, Primary Cell and Media Company

Supplier: Cell Systems

Our primary human cells offer unmatched consistency and a more biologically relevant tool than other cell types. Our cells are antibody-free and come from a deep inventory to help researchers with reproducibility and improved human insights.

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Cell Systems Human Pancreatic Microvascular Endothelial Cells, Primary Cell and Media Company

Cell Systems Human Pancreatic Microvascular Endothelial Cells, Primary Cell and Media Company

Supplier: Cell Systems

Our primary human cells offer unmatched consistency and a more biologically relevant tool than other cell types. Our cells are antibody-free and come from a deep inventory to help researchers with reproducibility and improved human insights.

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Cell Systems Human Lung Microvascular Endothelial Cells, Primary Cell and Media Company

Cell Systems Human Lung Microvascular Endothelial Cells, Primary Cell and Media Company

Supplier: Cell Systems

Our primary human cells offer unmatched consistency and a more biologically relevant tool than other cell types. Our cells are antibody-free and come from a deep inventory to help researchers with reproducibility and improved human insights.

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Cell Systems Human Microvascular Endothelial Cells, Primary Cell and Media Company

Cell Systems Human Microvascular Endothelial Cells, Primary Cell and Media Company

Supplier: Cell Systems

Our primary human cells offer unmatched consistency and a more biologically relevant tool than other cell types. Our cells are antibody-free and come from a deep inventory to help researchers with reproducibility and improved human insights.

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Cell Systems Human Liver Sinusoidal Endothelial Cells, Primary Cell and Media Company

Cell Systems Human Liver Sinusoidal Endothelial Cells, Primary Cell and Media Company

Supplier: Cell Systems

Our primary human cells offer unmatched consistency and a more biologically relevant tool than other cell types. Our cells are antibody-free and come from a deep inventory to help researchers with reproducibility and improved human insights.

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PHCbi MPR Series Upright Pharmaceutical Refrigerators, PHC Corporation

PHCbi MPR Series Upright Pharmaceutical Refrigerators, PHC Corporation

Supplier: PHC Corporation

These pharmaceutical refrigerators deliver a stable, reliable temperature control for clinical, pharmaceutical, biomedical storage and processing. Fast recovery following door openings assures safe storage during times of frequent access and high ambient conditions and to remove heat loads generated by powered instruments.

   Sustainable Options Available
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Blocking Buffer for Fluorescent Western Blotting, Rockland Immunochemicals

Supplier: Rockland Immunochemical

This blocking buffer is specifically formulated to achieve superior reproducible western blotting images using fluorescent systems.

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Anti-CD28 Mouse Monoclonal Antibody (PerCP (Peridinin-Chlorophyll Protein Complex)-Cy5.5®) [clone: CD28.2]

Anti-CD28 Mouse Monoclonal Antibody (PerCP (Peridinin-Chlorophyll Protein Complex)-Cy5.5®) [clone: CD28.2]

Supplier: Tonbo Biosciences

The CD28.2 antibody reacts with human CD28, a 44 kDa type I surface glycoprotein which acts as a co-stimulatory receptor in support of the T cell receptor (TCR). CD28 exists as a homodimer with specificity for two known ligands, known as B7-1 (CD80) and B7-2 (CD86), which are expressed on activated B cells and antigen-presenting cells. These ligands trigger CD28 signaling in concert with TCR activation to drive T cell proliferation, induce high-level expression of IL-2, impart resistance to apoptosis, and enhance T cell cytotoxicity. The interaction / co-stimulatory signaling between the B7 ligands and CD28 provides crucial communication between T cells and B cells or APCs to coordinate the adaptive immune response. Other members of the CD28 family of receptors include CTLA-4 (CD152), PD-1 (CD279), ICOS and BTLA.

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Anti-CD28 Mouse Monoclonal Antibody [clone: CD28.2]

Anti-CD28 Mouse Monoclonal Antibody [clone: CD28.2]

Supplier: Tonbo Biosciences

The CD28.2 antibody reacts with human CD28, a 44 kDa type I surface glycoprotein which acts as a co-stimulatory receptor in support of the T cell receptor (TCR). CD28 exists as a homodimer with specificity for two known ligands, known as B7-1 (CD80) and B7-2 (CD86), which are expressed on activated B cells and antigen-presenting cells. These ligands trigger CD28 signaling in concert with TCR activation to drive T cell proliferation, induce high-level expression of IL-2, impart resistance to apoptosis, and enhance T cell cytotoxicity. The interaction / co-stimulatory signaling between the B7 ligands and CD28 provides crucial communication between T cells and B cells or APCs to coordinate the adaptive immune response. Other members of the CD28 family of receptors include CTLA-4 (CD152), PD-1 (CD279), ICOS and BTLA.

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Cell Systems Human Brain Microvascular Endothelial Cells, Primary Cell and Media Company

Cell Systems Human Brain Microvascular Endothelial Cells, Primary Cell and Media Company

Supplier: Cell Systems

Our primary human cells offer unmatched consistency and a more biologically relevant tool than other cell types. Our cells are antibody-free and come from a deep inventory to help researchers with reproducibility and improved human insights.

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ABTS (Diammonium 2,2'-azinobis[3-ethyl-2,3-dihydrobenzothiazole-6-sulfonate]), light green powder

ABTS (Diammonium 2,2'-azinobis[3-ethyl-2,3-dihydrobenzothiazole-6-sulfonate]), light green powder

Supplier: MP Biomedicals

2,2-Azino-bis-(3-ethyl-benzthiazoline-6-sulfonic acid) (ABTS) has been used as a chromogenic substrate for horseradish peroxidase (HRP), both in general activity assays and in ELISA applications. Activity of HRP using ABTS appears about four-fold higher than using pyrogallol. It is mainly used as a substrate in sensitive peroxidase assays.
2,2′-Azino-bis(3-ethylbenzthiazoline-6-sulfonic acid) is a peroxidase substrate suitable for use in ELISA procedures. This substrate produces a soluble end product that is green in color and can be read spectrophotometrically at 405 nm. The reaction may be stopped with 1% sodium dodecyl sulfate (SDS). Recommended for ELISA (microwell) procedures, not recommended for membrane applications.

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E1-ClipTip™ Equalizer Adjustable Tip Spacing Multichannel Pipettors with Bluetooth Capability Promotion

Supplier: Thermo Scientific

Perform sample transfers between virtually any tube, rack, microplate, or horizontal gel box quickly and efficiently with adjustable tip spacing.

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MabSelect SuRe™ Affinity Chromatography Media, Cytiva

MabSelect SuRe™ Affinity Chromatography Media, Cytiva

Supplier: Cytiva

MabSelect SuRe™ is composed of a rigid, high-flow agarose matrix and alkali-tolerant rProtein A ligand. The ligand has been engineered to provide greater stability than conventional protein A-based media in the alkaline conditions used in CIP protocols. This enhanced alkali stability improves process economy and product quality.

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Cell Systems Human Retinal Microvascular Endothelial Cells, Primary Cell and Media Company

Cell Systems Human Retinal Microvascular Endothelial Cells, Primary Cell and Media Company

Supplier: Cell Systems

Our primary human cells offer unmatched consistency and a more biologically relevant tool than other cell types. Our cells are antibody-free and come from a deep inventory to help researchers with reproducibility and improved human insights.

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pNL3.2.CMV Vector, 20 µg, Promega

pNL3.2.CMV Vector, 20 µg, Promega

Supplier: Promega Corporation

NanoLuc (Nluc) luciferase is a small bright luminescent reporter enzyme (19.1kDa) engineered for optimal performance. Use the pNL3.2.CMV Vector as a negative control in experiments measuring regulated changes in NanoLuc luciferase expression.

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Anti-IL6 Mouse Monoclonal Antibody [clone: 1.2-2B11-2G10]

Anti-IL6 Mouse Monoclonal Antibody [clone: 1.2-2B11-2G10]

Supplier: Prosci

IL-6 is reported to be produced by fibroblasts, activated T cells, activated monocytes or macrophages and endothelial cells. It acts upon a variety of cells including fibroblasts, myeloid progenitor cells, T cells, B cells and hepatocytes. In addition, IL-6 appears to interact with IL2 in the proliferation of T lymphocytes. IL-6 potentiates the proliferative effect of IL-3 on multipotential hematopoietic progenitors. IL-6 is a multifunctional 24 kDa protein originally discovered in the medium of RNA stimulated fibroblastoid cells. It is upregulated by IL1, TNF, PDGF, IFN beta, TNF alpha, NGF, IL17 and downregulated by glucocorticoids IL4, TGF beta. IL-6 appears to be directly involved in the responses that occur after infection and cellular injury, and it may prove to be as important as IL1 and TNF alpha in regulating the acute phase response. IL6 has also been implicated in regulating adipose mass.

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Cell Systems Human Brain Pericytes, Primary Cell and Media Company

Cell Systems Human Brain Pericytes, Primary Cell and Media Company

Supplier: Cell Systems

Our primary human cells offer unmatched consistency and a more biologically relevant tool than other cell types. Our cells are antibody-free and come from a deep inventory to help researchers with reproducibility and improved human insights.

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TSX Series High-Performance Chromatography Refrigerators, Thermo Scientific

TSX Series High-Performance Chromatography Refrigerators, Thermo Scientific

Supplier: Thermo Fisher Scientific

The TSX high-performance chromatography refrigerators are designed for a variety of applications requiring close temperature control, full access to chromatography instrumentation, and easy set-up of instrumentation and apparatus within the chamber. The TSX chromatography series features industry-leading safety features to ensure maximum protection.

   Sustainable Options Available
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Phorbol-12-myristate-13-acetate ≥99%, colorless material

Supplier: MP Biomedicals

PMA (Phorbol-12-Myristate-13-Acetate) is a diester of phorbol and is a tumor promoting compound extracted from croton oil. It is a reversible, highly potent protein kinase C (PKC) activator in vitro and in vivo at nM concentrations. PMA’s effects on PKC are attributed to its similarity to diacylgylerol, a natural activator of PKC.
PMA activates Ca2+- ATPase and potentiates forskolin-induced cAMP formation. It has been shown to inhibit apoptosis induced by the Fas antigen, but PMA induces apoptosis in HL-60 promyelocytic leukemia cells.
Potent tumor promoter; activates protein kinase C in vivo and in vitro.
Store at -20 °C. Protect from light.

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Cell Systems Human Glomerular Microvascular Endothelial Cells, Primary Cell and Media Company

Cell Systems Human Glomerular Microvascular Endothelial Cells, Primary Cell and Media Company

Supplier: Cell Systems

Our primary human cells offer unmatched consistency and a more biologically relevant tool than other cell types. Our cells are antibody-free and come from a deep inventory to help researchers with reproducibility and improved human insights.

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pNL3.2[NlucP/minP] Vector, 20 µg, Promega

pNL3.2[NlucP/minP] Vector, 20 µg, Promega

Supplier: Promega Corporation

NanoLuc (Nluc) luciferase is a small enzyme (19.1kDa) engineered for optimal performance as a luminescent reporter. The pNL3.1[Nluc/minP] and pNL3.2[NlucP/minP] Vectors offer a minimal promoter for cloning response elements of interest.

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PRP-h1 Polymeric Reversed Phase HPLC Columns, Hamilton Company

PRP-h1 Polymeric Reversed Phase HPLC Columns, Hamilton Company

Supplier: Hamilton

Hamilton Company offers one of the most comprehensive selections of chromatography columns in the industry.

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Cell Systems Human Glomerular Mesangial Cells, Primary Cell and Media Company

Cell Systems Human Glomerular Mesangial Cells, Primary Cell and Media Company

Supplier: Cell Systems

Our primary human cells offer unmatched consistency and a more biologically relevant tool than other cell types. Our cells are antibody-free and come from a deep inventory to help researchers with reproducibility and improved human insights.

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Trichloroacetic acid (TCA) solution 6.1 N

Supplier: MP Biomedicals

Trichloroacetic acid is an acetic acid analogue commonly used to precipitate proteins, DNA and RNA. In the presence of SDS Trichloroacetic acid will precipitate proteins which can then be quantified by the Lowry method. The compound has also found uses as a decalcifier and fixative in microscopy, in protein sequencing, detecting albumin and organic synthesis.
Trichloroacetic acid is used in protein precipitation; has been used to determine protein concentration by quantitative precipitation. It is also used as a decalcifier and fixative in microscopy. A protocol for the precipitation of nucleic acids can be found in Molecular Cloning. Rats exposed to chronic sublethal amounts of trichloroacetic acid displayed an increase in serum bilirubin with a decrease in hematological proteins and cholesterols along with significant decreases in red blood corpuscles, mean cell volume, mean corpuscular hemoglobin, hemoglobin and hematocrit. In mice the production of liver tumors was associated to Trichloroacetic acid, which is also a known mouse hepatocarinogen. On the guinea pig trichloroacetic acid was observed to be a mild alergen on the skin.
+4 °C

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