"Peprotech"

Supplier: Peprotech

Produced from sera of rabbits immunized with highly pure Recombinant Murine IL-2. Anti­Murine IL-2­specific antibody was purified by affinity chromatography employing an immobilized Murine IL-2 matrix.

Supplier: Peprotech

Monoclonal AntibodyProduced in BALB/c x C57BL/6 F1-mice immunized with highly pure Recombinant Human IL-6. Anti­Human IL-6­specific antibody was purified from ascites fluid by Protein A affinity chromatography.

Supplier: Peprotech

Produced from sera of rabbits immunized with highly pure Recombinant Human Persephin. Anti­Human Persephin­specific antibody was purified by affinity chromatography employing an immobilized Human Persephin matrix.

Supplier: Peprotech

EGF Receptor (EGFR, ErbB1) is a transmembrane protein that exerts tyrosine kinase activity upon ligand-induced activation. EGFR can be activated by binding EGF, or at least six other structurally related protein ligands, including TGFα, HB-EGF, Betacellulin (BTC), Amphiregulin, Epiregulin, and Epigen. Upon activation, EGFR initiates a signaling cascade, which includes dimerization and internalization, tyrosine phosphorylation, DNA synthesis of target genes and, ultimately, cell proliferation. EGFR signaling plays a role in the growth and differentiation of normal cells, but elevated EGFR activity is correlated with the development and pathogenesis of certain cancers. Recombinant Human EGF Receptor (EGFR) is a 621 amino acid glycoprotein comprising the extracellular domain of EGFR, and migrates at an apparent MW of 97.5 kDa by SDS-PAGE analysis under reducing conditions.

Supplier: Peprotech

Produced from sera of rabbits immunized with highly pure Recombinant Human MCP-1 (CCL2). Anti­Human MCP-1 (CCL2)­specific antibody was purified by affinity chromatography and then biotinylated.

Supplier: Peprotech

Produced from sera of rabbits immunized with highly pure Recombinant Human IL-9. Anti­Human IL-9­specific antibody was purified by affinity chromatography employing an immobilized Human IL-9 matrix.

Supplier: Peprotech

Produced from sera of goats immunized with highly pure Recombinant Human TPO. Anti­Human TPO­specific antibody was purified by affinity chromatography employing an immobilized Human TPO matrix.

Supplier: Peprotech

Produced from sera of rabbits immunized with highly pure Recombinant Human I-309 (CCL1). Anti­Human I-309 (CCL1)­specific antibody was purified by affinity chromatography employing an immobilized Human I-309 matrix.

Supplier: Peprotech

CRP, Polyclonal antibody, Host: Rabbit, Species: Human, Immunogen: E.coli-derived, 23.2 kDa Recombinant Human CRP, Application: Sandwich ELISA, Western Blot, Purity: affinity chromatography, Size: 100UG

Supplier: Peprotech

SCF is a hematopoietic growth factor that exerts its activity by signaling through the c-Kit receptor. SCF and c-Kit are essential for the survival, proliferation and differentiation of hematopoietic cells committed to the melanocyte and germ cell lineages. Human SCF manifests low activity on murine cells, while murine and rat SCF are fully active on human cells. The human SCF gene encodes for a 273 amino acid transmembrane protein, which contains a 25 amino acid N-terminal signal sequence, a 189 amino acid extracellular domain, a 23 amino acid transmembrane domain, and a 36 amino acid cytoplasmic domain. The secreted soluble form of SCF is generated by proteolytic processing of the membrane anchored precursor. Recombinant Murine SCF is an 18.3 kDa polypeptide containing 165 amino acid residues, which corresponds to the sequence of the secreted soluble form of SCF. Manufactured using all Animal-Free reagents.

Supplier: Peprotech

β-NGF is a neurotrophic factor structurally related to BDNF, NT-3 and NT-4.  These proteins belong to the cysteine-knot family of growth factors that assume stable dimeric structures.  β-NGF is a potent neurotrophic factor that signals through its receptor β-NGFR, and plays a crucial role in the development and preservation of the sensory and sympathetic nervous systems.  β-NGF also acts as a growth and differentiation factor for B lymphocytes, and enhances B-cell survival.  The functional form of Recombinant Human β-NGF is a non-covalently-linked homodimer of two 13.5 kDa, polypeptide monomers that each contain 120 amino acids and three disulfide bonds, which are required for biological activity.Manufactured using all Animal-Free reagents.

Supplier: Peprotech

Midkine (MK) and the functionally-related protein pleiotrophin are heparin-binding neurotrophic factors that signal through the same receptor, known as anaplastic lymphoma kinase (ALK). MK plays an important regulatory role in epithelial-mesenchymal interactions during fetal development and in postnatal lung development. MK chemoattracts embryonic neurons, neutrophils and macrophages, and exerts angiogenic, growth and survival activities during tumorigenesis. Recombinant Human Midkine is a 13.4 kDa protein containing 123 amino acid residues including five intra-molecular disulfide bonds.

Supplier: Peprotech

Produced from sera of goats immunized with highly pure Recombinant Human Eotaxin-3 (CCL26). Anti­Human Eotaxin-3 (CCL26)­specific antibody was purified by affinity chromatography and then biotinylated.

Supplier: Peprotech

Produced from sera of rabbits immunized with highly pure Recombinant Human MIP-1β (CCL4). Anti­Human MIP-1β (CCL4)­specific antibody was purified by affinity chromatography employing an immobilized Human MIP-1β matrix.

Supplier: Peprotech

Human IL-31 is a T cell-derived cytokine that shares several structural and functional characteristics with IL-6, Oncostatin M, LIF, and Cardiotrophin-1. It signals through a receptor complex comprised of GPL (also known as gp130-like receptor or IL-31RA) and Oncostatin-M receptor (OSMR). GPL/OSMR signaling is a strong activator of STAT3 and STAT5, and can also activate STAT1, JAK1, and JAK2 signaling pathways. IL-31-regulated immune responses have been implicated in skin physiology and inflammatory skin diseases. Recombinant Human IL-31 is a 15.8 kDa protein containing 141 amino acid residues.

Supplier: Peprotech

VEGF is a potent growth and angiogenic cytokine. It stimulates proliferation and survival of endothelial cells, and promotes angiogenesis and vascular permeability. Expressed in vascularized tissues, VEGF plays a prominent role in normal and pathological angiogenesis. VEGF signals through three receptors; fms-like tyrosine kinase (flt-1), KDR gene product (the murine homolog of KDR is the flk-1 gene product) and the flt4 gene product. Due to its increased acidity, VEGF 121 circulates more freely than other VEGF forms, which bind more tightly with vascular heparin sulfates. Recombinant Human VEGF 121 is a 28.4 kDa, disulfide-linked homodimeric protein consisting of two 121 amino acid polypeptide chains.