146786 Results for: "N-(10-bromodec)phthalimide"

Supplier: Proteintech

MYOF, also named as FER1L3 and KIAA1207, belongs to the ferlin family. MYOF is calcium/phospholipid-binding protein that plays a role in the plasmalemma repair mechanism of endothelial cells that permits rapid resealing of membranes disrupted by mechanical stress. It is involved in endocytic recycling. MYOF implicated in VEGF signal transduction by regulating the levels of the receptor KDR. The antibody can recognize all the 8 isoforms of MYOF.

Supplier: Rockland Immunochemical

Sarcosine Oxidase is an inducible enzyme that catalyzes the oxidative demethylation of sarcosine to glycine, hydrogen peroxide, and 5,10-methylene-tetrahydrofolate in the presence of tetrahydrofolate and oxygen. Sarcosine oxidase is also able to oxidize cyclic amino acids such as L-proline and L-pipecolic acid, albeit at reduced rates.

Supplier: Bioss

SIGLEC10 is a putative adhesion molecule that mediates sialic-acid dependent binding to cells. It preferentially binds to alpha2,3- or 2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. In the immune response, may act as an inhibitory receptor upon ligand induced tyrosine phosphorylation by recruiting cytoplasmic phosphatase(s) via their SH2 domain(s) that block signal transduction through dephosphorylation of signaling molecules. SIGLEC10 interacts with PTPN6/SHP-1 upon phosphorylation. The protein is expressed by peripheral blood leukocytes (eosinophils, monocytes and a natural killer cell subpopulation).

Supplier: Proteintech

3-oxoacid-CoA transferase 1 (OXCT1), encoded by nuclear gene, is a mitochondrial CoA transferase required for ketone body degradation. It catalyzes the transfer of CoA from succinyl-CoA to acetoacetate, generating acetoacetyl-CoA. OXCT1 is expressed in brain, heart, and skeletal muscle, but not in liver. This antibody specifically recognizes endogenous OXCT1. (21209089)

Supplier: Proteintech

Tripartite motif-containing 14(TRIM14) belongs to the TRIM protein family that contains 3 zinc-binding domains, a RING, a B-box type1 and a B-box type2 and plays key roles in cellular proliferation, differentiation, development, transformation, and immune response mechanisms . TRIM4 inhibits the transcriptional activity of SPI1 in a dose-dependent manner. It may participate in the early stages of differentiation of embryonic stem cells, leading to the formation of embryoid bodies.

Supplier: Prosci

HNF4 was first identified as a DNA binding activity in rat liver nuclear extracts and then was found to be an orphan member of the nuclear receptor superfamily. Binding sites for this factor were identified in many tissue-specifically expressed genes, and the protein was found to be essential for early embryonic development in the mouse

Supplier: Biolegend

Alexa Fluor® 594 anti-mouse Ly-6G/Ly-6C (Gr-1) [RB6-8C5]; Isotype: Rat IgG2b, κ; Reactivity: Mouse; Apps: FC, IHC, IF; Size: 100 μg

Supplier: Proteintech

UBE2B(Ubiquitin-conjugating enzyme E2 B) is also named as RAD6B and belongs to the ubiquitin-conjugating enzyme family. Rad6B is an E2-conjugating enzyme, reported to mediate beta-catenin polyubiquitination and stabilization, thus activating the Wnt signaling pathway. The gene encodes a 152 amino acid protein. The Rad6B and Cdc34 proteins are significantly elevated in meiotic and postmeiotic haploid germ cells when chromatin modi?cations occur.

Supplier: Proteintech

PBK(PDZ-binding kinase) is also named as TOPK, CT84, Nori-3, SPK and belongs to the MAP kinase kinase subfamily. PBK may have a role in the regulation of cellular proliferation and progression of the cell cycle. It has a characteristic cdc2ycyclin B phosphorylation site(SyT-P-X-KyR) at its N terminus,which is conserved across species, and it is phosphorylated in a cell cycle-dependent manner at mitosis, and that this phosphorylation is required for its activation.

Supplier: Adipogen

DAF-2 is highly sensitive reagent for NO detection and determination of nitric oxide synthase activity. DAF-2, however, remains essentially nonfluorescent until it reacts with the nitrosonium cation (produced by spontaneous oxidation of nitric oxide) to form a fluorescent heterocycle, which becomes trapped in the cell's cytoplasm. This sensitive fluorescent probe has been used to identify individual nitric oxide-producing neurons in brain slices, in mitochondria and in living plant cells. Spectral data: lambdaex 505nm; lambdaem 518nm in 0.1M Tris pH8.0.

Supplier: Proteintech

BMI- 1 is one of polycomb group genes, which together with Ring1 strongly enhances the E3 ubiquitin ligase activity of the Ring2 catalytic subunit. Bmi1 plays an important role in the regulation of cell proliferation and senescence through repression of the p16Ink4a and p19Arf genes and is required for maintenance of adult hematopoietic and neural stem cells. The antibody reacts with the 37kd BMI1 protein.

Supplier: Prosci

In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins (By similarity).

Supplier: Proteintech

RRM1, also named as RR1, belongs to the ribonucleoside diphosphate reductase large chain family. RRM1 provides the precursors necessary for DNA synthesis. RRM1 catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.RRM1 is a key enzyme in DNA synthesis: low level expression of RRM1 is associated with poor survival. RRM1 is a prognostic marker of NSCLC. The antibody is specfic to RRM1.

Supplier: TrippNT

Wall mountable angled large pipette organizers feature five compartments to keep expensive pipettes clean, safe, and readily available.

Supplier: Bel-Art Products, a Part of SP

Extra-large Scienceware® desiccator cabinets provide a low-humidity, dust-free environment for several large containers or a lot more small ones.

Supplier: Genetex

PE-conjugated Mouse Monoclonal antibody [3G3] to FoxP3

Supplier: Antyila Scientific

Quickly heat and dry samples.

Supplier: Proteintech

RIOK3(Serine/threonine-protein kinase RIO3) is initially characterized as a homolog of Aspergillus nidulans sudD and showed down-regulation at the invasive front of malignant melanomas.On Western blots, human RIOK3 migrated as a 60-kD protein. Northern blot analysis indicated that the approximately 4-kb RIOK3 mRNA is expressed widely in human tissues, with additional smaller transcripts present in testis.

Supplier: Fujifilm Irvine Scientific

CD40-Ligand, or CD154, is a membrane glycoprotein and differentiation antigen that is expressed on the surface of T cells, monocytes, basophils, eosinophils, platelets, dendritic cells, and endothelial cells. CD40-Ligand binds and activates the CD40 receptor on antigen-presenting cells. CD40-Ligand stimulates B cell proliferation, immunoglobulin class switching, and antibody secretion. CD40-Ligand also induces cytokine production and tumoricidal activity in peripheral blood monocytes. CD40-Ligand is a co-stimulator of activated T cell proliferation and inflammatory protein production.

Supplier: Immunoreagents

ImmunoReagents’ Alkaline Phosphatase (AP) antibody conjugates are used in ELISA, Immunohistochemistry (IHC) and Western blotting techniques. AP is a 140 kDa enzyme that changes color in the presence of PNPP or BCIP/NBT substrates. These conjugates have a linear reaction rate thus allowing the researcher to increase sensitivity by prolonging substrate incubation times.

Supplier: Bel-Art Products, a Part of SP

Store pipettors while protecting pipettor tips in these epoxy-coated aluminum racks that provide quick, easy access for more efficient work.

Supplier: National Public Seating

The 800 Series lightweight institutional-grade folding chair offers the perfect solution for both indoor and outdoor seating events such as meetings, graduations and receptions. Designed for indoor or outdoor events - inverted rear leg u-brace prevents sinking into ground.

Supplier: National Public Seating

The 84 Series Double-Tiered Hanging Chair Dolly is a wise choice for saving time and space in busy multipurpose environments.

Supplier: KEYSTONE ADJUSTABLE CAP CO., INC.

Continuous Form tubing made from 1422A Tyvek® provides the user with tremendous sizing flexibility when wrapping pharmaceutical equipment for steam sterilization.

Supplier: MP Biomedicals

Dextran sulfate is a polyanionic derivative of dextran produced by esterification of Dextran with chlorosulphonic acid. Dextran sulfate sodium (DSS) is the sodium salt which is a white to off-white powder freely soluble in water and salt solutions to form a stable, clear solution. The sulfur content is approximately 17% which corresponds to an average of 1.9 sulfate groups per glucosyl residue of the dextran molecule.

Supplier: NEWARK/ELEMENT 14 TE

EX series point and shoot thermal imaging camera with 80×60 pixels IR resolution and 320×240 MSX resolution.

Supplier: Biotium

Membrane-permeant form of Rhod-590 calcium indicator dye that can be loaded into cells via incubation. Because of the relatively low water solubility of the AM ester, Pluronic F-127, a mild detergent, is often used as a dispersing agent to facilitate dye loading. Rhod-590 AM ester itself does not bind Ca2 , but it is readily hydrolyzed to Rhod-590 by endogenous esterases once it enters cells.

Supplier: Elma

Elma Lab Clean A20SF solution cleans pipettes and volumetric ware in ultrasonic cleaners and spray washers. Cleaned glass surfaces are free of surfactants and allow undisturbed draining of liquids.

Supplier: PG Lifelink

LabLink Surface Mount Raceway (Versa-Duct), made from anodized extruded aluminum, offers a superior design to combine electrical and/or data into one unified system.

Supplier: TCI America

CAS Number: 582-52-5
MDL Number: MFCD00005544
Molecular Formula: C12H20O6
Molecular Weight: 260.29
Purity/Analysis Method: >97.0% (GC)
Form: Crystal
Melting point (°C): 110
Specific rotation [a]20/D: -18.5 deg (C=5, H2O)