Supplier: Honeywell Research Chemicals

High purity solvents for speciation analysis by LC-ICP-MS. Rigorous purification procedures followed by UV spectroscopy, IC, and ICP-MS testing to assure high chemical purity and high UV transmittance. The blank values for metal traces in these solvents are in the ppb range or lower.

Supplier: TCI America

[Ion-Pair Reagent for LC-MS]
CAS Number: 114389-69-4
MDL Number: MFCD03093617
Molecular Formula: C8H19NO2
Molecular Weight: 161.25
Form: Clear Liquid
Color: Colorless

Supplier: TCI America

[Ion-Pair Reagent for LC-MS]
CAS Number: 19070-91-8
MDL Number: MFCD00191381
Molecular Formula: C8H19N
Molecular Weight: 189.30
Form: Clear Liquid
Color: Colorless

Supplier: Thermo Scientific

Use with Thermo Scientific™ Acclaim Carbamate LC columns to achieve baseline separation of carbamate pesticides (N-methylcarbamate and N-methylcarbamoyloxime pesticides) specified in US EPA Method 531.2.

Supplier: AGILENT TECHNOLOGIES, INC (CSD)

Agilent is an expert in speciation analysis, offering HPLC-ICP-MS parts and interface supplies.

Supplier: Promega Corporation

The mass spectrometry-compatible human protein extracts are designed for monitoring mass spectrometry instrument performance. The extracts are predigested and cleaned up by solid-phase extraction for immediate use in liquid chromatography/mass spectrometry (LC-MS) analysis.

Supplier: AGILENT TECHNOLOGIES, INC (CSD)

Syringe filters are often used to clarify small-volume samples before HPLC and ion chromatography.

Supplier: SCIEX

Libraryview Software Version 1.3, for OS offers a comprehensive set of user-friendly tools for the analysis of full scan LC/MS/MS data, From managing spectral libraries to interactively reviewing spectral matches and reporting

Supplier: MP Biomedicals

Miscible in ethanol (0.1 mL/mL, v/v - clear, colorless solution). It can be used at concentration of 0.1% in the mobile phase of an HPLC/LC-MS protocol for the detection of marine bacterioplankton siderophores.

Supplier: Honeywell Research Chemicals

Acetonitrile with 0.1% acetic acid, CHROMASOLV* LC-MS, LabReady* Solvent Blend, size: 4l

Supplier: Eagle Biosciences

IAC use in clean-up of single mycotoxins of complex feed extracts is well known in lab work.

Supplier: BioVendor

Total 466 AA. MW: 53.0 kDa (calculated). UniProtKB acc. No. P08254 (Tyr18–Cys477). C-terminal His-tag (6 AA). Protein identity confirmed by LC-MS/MS.

Supplier: G-Biosciences

G-Biosciences' InGel™ Silver provides a complete set of reagents for the in gel tryptic digestion and extraction of peptides for mass spectrometry (MALDI and LC MS/MS)

Supplier: SCIEX

The Sciex Triple Quad 4500 System is a high sensitivity, bench top triple quadrupole mass spectrometer designed for LC-MS/MS analyses. This instrument provides excellent robustness and long term stability for the most demanding assays.

Supplier: Thermo Scientific

Achieve exceptional peak shape and resolution for your HPLC and LC/MS applications with Thermo Scientific Hypersil GOLD HPLC columns.

Supplier: AGILENT TECHNOLOGIES, INC (CSD)

PEEK lined stainless steel HILIC columns for LC/MS analysis of underivatized amino acids.

Supplier: Genscript

Payloads are the important components of antibody-drug conjugates (ADCs). The most commonly used ADC payloads are MMAE, DM1, and DXd. ADC pharmacokinetic (PK) studies include free payload analysis, conjugated antibody analysis, and total antibody analysis via ligand-binding assay (LBA) and LC-MS/MS assay. The anti-payload antibody is a useful reagent in PK assay for determining conjugated antibodies. It can be used as a capture antibody to determine the conjugated antibody in LBA assay or through immunocapture to enrich the ADC sample in LC-MS/MS assay. The DM1, also known as mertansine, is a microtubule polymerization inhibitor. Trastuzumab emtansine (T-DM1), composed of trastuzumab conjugated to DM1, is a type of targeted cancer drug for breast cancer treatment. T-DM1 is targeted toward HER2 (ERBB2) positive breast cancer.

Supplier: TCI America

[Ion-Pair Reagent for LC-MS]
CAS Number: 422-64-0
MDL Number: MFCD00004170
Molecular Formula: C3HF5O2
Molecular Weight: 164.03
Form: Clear Liquid
Color: Colorless

Supplier: BioVendor

Total 462 AA. MW: 51.0 kDa (calculated). UniProtKB acc. No. P01019 (Asp34-Ala485). C-terminal linker (2 extra AA) and C-terminal FLAG-tag (8 extra AA). Protein identity confirmed by LC-MS/MS.

Supplier: Honeywell Research Chemicals

Methanol with 0.1% acetic acid, CHROMASOLV* LC-MS, LabReady* Solvent Blend, >/=99.5%, size: 4l

Supplier: Honeywell Research Chemicals

High purity solvents for speciation analysis by LC-ICP-MS. Rigorous purification procedures followed by UV spectroscopy, IC, and ICP-MS testing to assure high chemical purity and high UV transmittance. The blank values for metal traces in these solvents are in the ppb range or lower.

Supplier: Restek

Force Biphenyl LC HPLC Columns are ideal for bioanalytical testing applications like drug and metabolite analyses.

Supplier: BioVendor

UniProtKB acc. No. P10909. Protein identity confirmed by LC-MS/MS.

Supplier: AGILENT TECHNOLOGIES, INC (CSD)

High-quality glass and stainless steel solvent filters with different pore sizes for LC applications.

Supplier: BioVendor

Native protein isolated from pooled human serum, 312 AA. MW: 34,35 kDa (calculated without glycosylation). Protein identity confirmed by LC-MS/MS (NCBI no. gi|16418467).

Supplier: BioVendor

Total 133 AA. MW: 15.33 kDa (calculated). UniProtKB acc.no. P22749 (Arg23-Leu145). N-Terminal His-tag (10 extra AA). Protein identity confirmed by LC-MS/MS.

Supplier: Invitrogen

Thermo Scientific™ Pierce™ High pH Reversed-Phase Peptide Fractionation Kit increases protein identification from LC/MS analysis through orthogonal peptide fractionation of complex peptide samples.Easy-to-use—resin provided in single-use spin column formatImproved protein identifications—protein identifications increased by ≥50% when compared to unfractionated samplesReproducible—elution profiles and fractional resolution vary by less than 20%Optimized—robust procedure for maximal protein identification and peptide recovery while minimizing fractional overlapCompatible—reagents validated with a variety of complex samples, including TMT™-labeled peptidesIn order to enable deep proteome sequencing, it is often necessary to reduce the sample complexity by fractionation in an orthogonal dimension prior to LC/MS analysis. The Pierce High pH Reversed-Phase Peptide Fractionation Kit utilizes high pH reversed-phase chromatography to separate peptides by hydrophobicity and provides excellent orthogonality to low pH reversed-phase LC-MS gradients.The kit has been designed to improve protein identification through the use of a proprietary reversed-phase resin in an easy-to-use spin column format with a highpH fractionation protocol. In contrast to strong cation exchange (SCX) fractionation, the high-pH reversed-phase fractions do not require an additional desalting step before LC/MS analysis.The High pH Reversed-phase Peptide Fractionation Kit includes a high pH buffer (0.1% triethylamine) and twelve spin columns containing pH-resistant reversed-phase resin. Each reversed-phase fractionation spin column enables fractionation of 10–100 µg of peptide sample using a microcentrifuge.Native, phosphorylated, Tandem Mass TagTM (TMTTM)-labeled, and other complex peptide mixture samples can be fractionated using this kit. Combining the search results generated by the individual fractions helps improve protein sequence coverage and increases the number of identified proteins relative to unfractionated samples.Applications:Reducing sample complexity to identify targets of interestConducting systems biology studiesReducing sample complexity to improve quantitation studies

Supplier: Honeywell Research Chemicals

LabReady™ Solvent Blends

Supplier: Restek

The innovative Biphenyl is Restek's most popular LC stationary phase because it is particularly adept at separating compounds that are hard to resolve or that elute early on C18 and other phenyl chemistries.

Supplier: Thermo Scientific

Nanoflow LC-MS utilizes very narrow fused silica columns and as a result, even the slightest inconsistency in column connection can result in leaks and dead volumes are a frequent source of poor data, causing unstable spray and a significant loss in performance.