4692 Results for: "Enzo Life Sciences"
Tobramycin (from Streptomyces tenebarius)
Supplier: Enzo Life Sciences
White to off-white powder
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Pristimerin (from Tripterygium wilfordii Hook.F) ≥97% (by HPLC)
Supplier: Enzo Life Sciences
Triterpenoid. Antitumor agent. Induces caspase-dependent apoptosis by inhibiting the chymotrypsin-like activity of the proteasome. Inhibits NF-κB activation via inhibition of IKKα or IKKβ. Inhibits induction of inducible nitric oxide synthase (iNOS; NOS II). Shows in vitro antimalarial and insecticidal activity. Induces mitochondrial cell death. Has antiproliferative, antifungal and antiviral properties. Potent and reversible monoacylglycerol lipase (MGL) inhibitor.
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4-(Dimethylamino)-N-[7-(hydroxyamino)-7-oxoheptyl]benzamide ≥98% (by HPLC)
Supplier: Enzo Life Sciences
Potent inhibitor of histone deacetylases (HDACs) (IC50≤1µM).
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DL-α-Difluoromethylornithine hydrochloride monohydrate ≥98% (by TLC)
Supplier: Enzo Life Sciences
Inhibitor of ornithine decarboxylase and arginase
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Tyrphostin AG 1024 ≥98% (by HPLC and UV method)
Supplier: Enzo Life Sciences
Specific inhibitor of insulin-like growth factor-1 (IGF-1) and insulin receptor kinases. Induces apoptosis by downregulation of the expression of phospho-Akt1 and Bcl-2. Also increases Bax, p53 and p21 expression.
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Genistein (synthetic) ≥99% (by HPLC)
Supplier: Enzo Life Sciences
Tyrosine kinase inhibitor
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Curcumin (from Curcuma longa) ≥98% (by HPLC), high purity
Supplier: Enzo Life Sciences
Inhibitor of Lipoxygenase and COX
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Catharanthine tartrate (from Catharanthus roseus) ≥90% (dry basis)
Supplier: Enzo Life Sciences
Starting material for the synthesis of the antitumor drugs vinblastine and vincristine. It is less active as an inhibitor of tubulin self-assembly into microtubules than the latter two compounds.
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EB-47 dihydrochloride dihydrate
Supplier: Enzo Life Sciences
PARP-1 inhibitor
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TIQ-A ≥96% (by HPLC)
Supplier: Enzo Life Sciences
Potent poly(ADP-ribose) polymerase-1 (PARP-1) inhibitor (IC50=450nM). Neuroprotectant.
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(-)-Arctiin (from Arctium lappa) ≥95% (by HPLC)
Supplier: Enzo Life Sciences
Lignan derivative with antitumor activities. Down-regulates anti-apoptotic protein Bcl-XL. Potent inhibitor of HIV type-I integrase and DNA topoisomerase II. Shows phytoestrogenic activity and is an antagonist for platelet activating factor and Ca2+.
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Pseudohypericin ≥98% (by HPLC, TLC)
Supplier: Enzo Life Sciences
Inhibitor of PKC and dopamine beta-hydroxylase
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Bufotalin ≥98% (by HPLC)
Supplier: Enzo Life Sciences
Na+/K+ ATPase inhibitor
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Tentoxin (from Alternaria alternata) ≥98% (by HPLC, TLC)
Supplier: Enzo Life Sciences
Cyclic tetrapeptide. Inhibitor of chloroplast F1-ATPase (CF1). Does not inhibit the homologous enzymes from chloroplasts of insusceptible plant species or from bacteria or mitochondria.
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Rocaglamide ≥98% (by HPLC)
Supplier: Enzo Life Sciences
NF-kappaB inhibitor
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(-)-Eburnamonine ≥99%
Supplier: Enzo Life Sciences
Antihypoxic. Vasodilator.
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Diphenylboric acid-2-aminoethyl ester (2-APB) ≥98% (by HPLC)
Supplier: Enzo Life Sciences
Cell permeable modulator of Ins(1,4,5)-P3-induced Ca2+ release. A prototype drug for a group of structurally related calcium channel blockers in human platelets. Has been shown, in the absence of other stimuli, to activate TRPV1, V2 and V3, but not TRPV4, V5 and V6 expressed in HEK 293 cells. Potentiates the effect of capsaicin, protons and heat on TRPV1. It was originally introduced as an IP3 receptor blocker and subsequently as an inhibitor of store-operated Ca2+ entry (75µM).