"Biotium"

Supplier: Biotium

This MAb recognizes full-length MUC1 in a glycosylation-independent manner and can bind to the fully glycosylated protein. The dominant epitope of this MAb is APDTR in the VNTR region. It reacts with the core peptide of the MUC1 protein, which is a member of a family of mucin glycoproteins that are characterized by high carbohydrate content, O-linked oligosaccharides, high molecular weight (>200 kDa) and an amino acid composition rich in serine, threonine, proline and glycine. The core protein contains a domain of 20 amino-acid tandem repeats that functions as multiple epitopes for the MAb. Incomplete glycosylation of some tumor-associated mucins may lead to variable unmasking of the multiple peptide epitopes leading to the observed differences in staining intensity between normal and malignant tissues. This MAb reacts with both normal and malignant epithelia of various tissues including breast and colon.

CF® dyes are Biotium's next-generation fluorescent dyes. CF®568 is a red fluorescent dye (Ex/Em 562/583 nm) with superior brightness and photostability. It also is compatible with super-resolution imaging by STORM and TIRF.

Supplier: Biotium

WT1 (Wilm's Tumor 1), Monoclonal antibody, Clone: WT1/857 + 6F-H2, Host: Mouse, Species reactivity: Mouse, Rat, Human, Isotype: IgG1, kappa, Conjugate: CF405M, Immunogen: Recombinant protein with residues 1-181 human WT1, Synonym: WT1, Size: 500uL

Supplier: Biotium

Involucrin, Monoclonal antibody, Clone: IVRN/827, Host: Mouse, Species reactivity: Human, Isotype: IgG1, kappa, Conjugate: biotin, Immunogen: Purified involucrin from human keratinocytes, Synonyms: IVL, Application: Immunofluorescence, Flow cytometry, Size: 500uL

Supplier: Biotium

The spiral shaped bacterium Helicobacter pyloriis strongly associated with inflammation of the stomach and is also implicated in the development of gastric malignancy. H. pylori is known to cause peptic ulcers and chronic gastritis in humans. It is associated with duodenal ulcers and may be involved in development of adenocarcinoma and low-grade lymphoma of mucosa associated lymphoid tissue in the stomach. This antibody stains the individual H. pylori bacterium when it presents on the surface of the epithelium or in the cytoplasm of the epithelial cells in biopsy tissue sections from the antrum and body of the stomach.

Supplier: Biotium

EGFr Monoclonal antibody, Clone: 31G7, Host: Mouse, Species reactivity: Human, Isotype: IgM, kappa, Conjugate: CF405S, Immunogen: Human EGFR purified from A431 cells, Synonyms: Erbb1, ERBB1, Application: IF, IHC, FC, Size: 100uL

Supplier: Biotium

This MAb recognizes a 60 kDa antigen associated with the mitochondria in human cells. It is a part of a new panel of reagents, which recognizes subcellular organelles or compartments of human cells. These markers may be useful in identification of these organelles in cells, tissues, and biochemical preparations. It recognizes an antigen associated with the mitochondria in human cells only. It can be used to stain the mitochondria in cell or tissue preparations and can be used as a mitochondrial marker in subcellular fractions. It produces a spaghetti-like pattern in normal and malignant cells and may be used to stain mitochondria of cells in fixed or frozen tissue sections. It can also be used with paraformaldehyde fixed frozen tissue or cell preparations. This MAb is an excellent marker for human cells in xenographic model research. It reacts specifically with human cells, including neurons and embryonic stem cells.

CF® dyes are Biotium's next-generation fluorescent dyes. CF®647 is a far-red fluorescent dye (Ex/Em 650/665 nm) with excellent brightness. It also is compatible with super-resolution imaging by STORM.

Supplier: Biotium

This antibody recognizes both the free and protein-conjugated (either soluble or cell bound) form of biotin. This MAb is highly specific to biotin and shows no cross-reaction with other structurally related compounds. It has a very high affinity for biotin and is excellent for use in various amplification techniques. In some applications, localization of biotinylated probes with avidin produces unacceptably high background staining. Anti-biotin antibody may be substituted to decrease this noise.

CF® dyes are Biotium's next-generation fluorescent dyes. CF®488A is a green fluorescent dye (Ex/Em 490/515 nm) with excellent brightness and photostability. The dye is minimally charged for less non-specific binding. CF®488A also is compatible with super-resolution imaging by TIRF.

Supplier: Biotium

CD8 Monoclonal antibody, Clone: C8/468 + C8/144B, Host: Mouse, Species reactivity: Human, Isotype: IgG1, K, Conjugate: CF405S, Immunogen: A 13 amino acid synthetic peptide, C-term, Synonyms: T8/Leu-2, Application: IF, Size: 100uL

Supplier: Biotium

Cytokeratin 18 Monoclonal antibody, Clone: DA7, Host: Mouse, Species reactivity: Human, Isotype: IgG1, kappa, Conjugate: CF568, Immunogen: Human breast cancer PMC 42 cells, Synonyms: K18, Application: IF, IHC, WB, FC, Size: 500 uL

Supplier: Biotium

GnRH-Receptor (LHRH Receptor), Monoclonal antibody, Clone: F1G4, Host: Mouse, Species reactivity: Human, Isotype: IgG1, kappa, Conjugate: CF488A, Immunogen: A synthetic peptide aa 1-29 from the N-terminal of human GnRH receptor, Application: IF, Flow, Size: 100uL

Supplier: Biotium

Granulocyte Marker, Monoclonal antibody, Clone: BM-2, Host: Mouse, Species reactivity: Human, Isotype: IgG1, Conjugate: CF640R, Immunogen: Human peripheral blood mononuclear cells, Synonyms: Myeloid specific protein; p183 DNA-binding cytoplasmic protein, Size: 500uL

Supplier: Biotium

Kit provides a range of calibration buffers with accurate calcium concentrations and is useful for the calibration of fluorescent Ca² indicators (1,2).

Supplier: Biotium

Granulocyte Marker, Monoclonal antibody, Clone: BM-1, Host: Mouse, Species reactivity: Human, Isotype: IgG1, Conjugate: CF488A, Immunogen: Human peripheral blood mononuclear cells, Synonyms: Myeloid specific protein; p183 DNA-binding cytoplasmic protein, Size: 500uL

Supplier: Biotium

CD11c Monoclonal antibody, Clone: HC1/1, Host: Mouse, Conjugate: CF640R, Species reactivity: Human, Isotype: IgG1, kappa, Immunogen: Human monocytic U937 phorbol ester-treated cells, Application: IF, FC, Size: 500 uL

Supplier: Biotium

This monoclonal antibody is part of a new panel of reagents, which recognizes subcellular organelles or compartments of human cells. These markers may be useful in identification of these organelles in cells, tissues, and biochemical preparations. This MAb recognizes the double stranded DNA in human cells. It can be used to stain the nuclei in cell or tissue preparations and can be used as a nuclear marker in human cells. This MAb produces a homogeneous staining pattern in the nucleus of normal and malignant cells.,Double Stranded deoxyribonucleic acid (ds DNA) is the genetic material of all cells and many viruses and is a polymer of nucleotides. The monomer consists of phosphorylated 2-deoxyribose N-glycosidically linked to one of four bases, adenine, cytosine, guanine or thymine. These are linked together by 3',5'-phosphodiester bridges. In the Watson-Crick double-helix model, two complementary strands are wound in a right-handed helix and held together by hydrogen bonds between complementary base pairs.

CF® dyes are Biotium's next-generation fluorescent dyes. CF®640R is a far-red fluorescent dye (Ex/Em 642/662 nm) with excellent brightness, and the best photostabiity among spectrally-similar dyes.

Supplier: Biotium

CD16Monoclonal antibody, Clone: ICO-116, Host: Mouse, Conjugate: CF405S, Species reactivity: Human, Isotype: IgG's, Immunogen: Human CD16 proteinUnigene 372679, Application: Immunofluorescence, Flow cytometry, Size: 100uL