2405 Results for: "BioVendor"

Supplier: BioVendor

N-terminal domain of alpha-dystroglycan is secreted into the cerebrospinal fluid. Its effect on the nervous system remains unclear. The complete dystroglycan complex is expressed in a variety of tissues and plays a role in processes such as laminin and basement membrane assembly, sarcolemmal stability, cell survival, peripheral nerve myelination, nodal structure, cell migration, and epithelial polarization.

Supplier: BioVendor

Total 490 AA. MW: 55.8 kDa (calculated). UniProtKB acc. No. Q9Y5X9 (Ser21–Pro500). N-terminal linker (2 extra AA), C-terminal linker (2 extra AA) and C-terminal His-tag (6 extra AA). Protein identity confirmed by LC-MS/MS.

Supplier: BioVendor

Total 438 AA, M.w. 51.27kDa (calculated). The AA sequence (AA 1–427) is identical to Swiss-Prot-P10909 (AA 23–449, secreted Human Clusterin). C-terminal Flag-tag, 11 extra AA (highlighted).

Supplier: BioVendor

The mouse/rat obestatin EIA assay kit developed by our laboratory can be used for direct determination of serum obestatin level’s variation.

Supplier: BioVendor

Interleukin-17 is involved in the regulation of hematopoiesis and its effects are dependent on the physiological/pathological status of the organism.

Supplier: BioVendor

IL-8 (8 kDa, 72 amino acids) is a non-glycosylated protein and it is produced by the processing of a precursor protein of 99 amino acids.

Supplier: BioVendor

Total 295 AA. MW: 31.3 kDa (calculated). UniProtKB acc.no. Q8TCT1. N-Terminal His-tag 14 AA (highlighted).

Supplier: BioVendor

Total 102 AA. MW: 11.99 kDa (calculated). UniProtKB acc.no. P33763. N-Terminal His-tag, 10 extra AA

Supplier: BioVendor

GH is a member of the somatotropin/prolactin family of hormones which play an important role in growth control. The gene, along with four other related genes, is located at the growth hormone locus on chromosome 17 where they are interspersed in the same transcriptional orientation; an arrangement which is thought to have evolved by a series of gene duplications. The five genes share a remarkably high degree of sequence identity. Alternative splicing generates additional isoforms of each of the five growth hormones, leading to further diversity and potential for specialization. This particular family member is expressed in the pituitary but not in placental tissue as is the case for the other four genes in the growth hormone locus. Mutations in or deletions of the gene lead to growth hormone deficiency and short stature.

Supplier: BioVendor

Quality control test, Indirect ELISA – to determine titer of the antibody , SDS PAGE – to determine purity of the antibody, and BCA - to determine quantity of the antibody.

Supplier: BioVendor

Total 269 AA. MW: 30.2 kDa (calculated). UniProtKB acc.no. Q9NP85 (Val125-Leu383). N-terminal His-tag (10 extra AA). Protein identity confirmed by LC-MS/MS.

Supplier: BioVendor

Total 156 AA. MW: 17.8 kDa (calculated). UniProtKB acc.no. P48304. N-Terminal His-tag 12 AA

Supplier: BioVendor

Adiponectin has the potential to become a clinically relevant parameter to be measured routinely in subjects at risk for type 2 diabetes, atherosclerosis and the metabolic syndrome.

Supplier: BioVendor

96 wells (1 kit) - ELISA is a competitive enzyme immunoassay for the quantitative measurement of anti-dsDNA.

Supplier: BioVendor

96 wells (1 kit) - ELISA is a sandwich enzyme immunoassay for the quantitative measurement of anti-SARS-CoV-2 nucleocapsid protein.

Supplier: BioVendor

Total 286 AA. MW: 33.3 kDa (calculated). N-terminal His-tag, 10exrea AA. The AA sequence is identical to UniProtKB/Swiss-Prot entry O76038.

Supplier: BioVendor

Leucine-rich alpha-2-glycoprotein (LRG) is a secretory type 1 acute phase protein whose expression is upregulated by the mediators of acute-phase response. The level of LRG in the blood increases during microbial infections and cancer, presumably as a result of the liver’s response to pro-inflammatory cytokines . The function of LRG is unknown but it is proved that LRG is tightly binding to Cyt C. It is suggested that extracellular Cyt C that is released from the cell death by an acute inflammation could be trapped to form tight complex with LRG and be excluded from circulation. LRG secretion by human hepatoma cells is increased by treatment with a mixture of cytokines including IL-6, IL-1b, and TNFα that are known to induce acute-phase proteins.

Supplier: BioVendor

The Cell-Clock Assay is a live-cell detection and measurement system that can be employed to monitor the four major phases of the mammalian cell cycle during in vitro culture

Supplier: BioVendor

Total 169 AA. MW: 19,2 kDa (calculated). UniProtKB acc.no. O95760. N-Terminal His-tag, 10 extra AA

Supplier: BioVendor

Cytokine-like protein 1 is a secreted protein. It is expressed in CD34+ cell populations of bone marrow and cord blood which function as hematopoietic stem/progenitor cells. It is not expressed in CD34– cells. Experiments with knock-out mice (Cytl1-/-) suggest that CYTL1 is required for the maintenance of cartilage homeostasis rather than cartilage and bone development, and loss of CYTL1 function is associated with experimental osteoarthritic cartilage destruction in mice.

Supplier: BioVendor

Cornifin-B occurs in keratinocytes. It is cross-linked to membrane proteins by transglutaminase which leads to formation of an insoluble envelope. It is expressed during differentiation in squamous tissues such as epidermis, esophagus, tongue or trachea.

Supplier: BioVendor

Total 840 AA, UniProt P22413 (Lys98-Asp925). MW: 96.5 kDa (calculated), migrates at ~ 110 kDa on SDS PAGE; N-terminal linker (2 extra AA), C-terminal linker (4 extra AA) and C-terminal His-tag (6 extra AA). Protein identity confirmed by LC-MS/MS.

Supplier: BioVendor

Neuroserpin (NSP; alternative names: serpin I1, peptidase inhibitor 12, PI-12) is a secreted glycoprotein which consists of 410 amino acid residues (46.4 kDa – if taken without glycosylation) including 16 amino acids of potential signal peptide. Neuroserpin-coding gene (PI12) consists of 9 exons and 8 introns and has a strongly conserved gene organization. Neuroserpin is a serine protease inhibitor of the serpin family that has been identified as an axonally secreted glycoprotein in neuronal cultures of chicken dorsal root ganglia.

Supplier: BioVendor

Human Lecithin: cholesterol acyltransferase (LCAT) is a glycoprotein with a molecular mass of approximately 58 kDa.

Supplier: BioVendor

Dickkopf-1 (Dkk-1) is encoded by the gene dickkopf together with other members of dickkopf protein family in vertebrates.

Supplier: BioVendor

Trefoil factor 3 (TFF3, also known as intestinal trefoil factor) belongs together with TFF1 and TFF2 to a small group of mucin-associated peptides. TFF3 contains seven cysteine residues, six of which form disulfide bonds to create a characteristic three-leafed structure. Due to its compact structure, TFF3 is extremely resistant toward acids, proteolytical cleavage or heat degradation. Monomeric form of TFF3 consists of 60 amino acids and has 6.7 kDa, while the dimer (13.1 kDa) consists of 118 amino acids. TFF3 is expressed mainly in gastrointestinal tract, in the mucous cells of the small and large intestine, where it maintains the integrity of mucous layer and in cooperation with mucins protects the gastrointestinal epithelial cells against various injurious agents. However, TFF3 was also detected in salivary glands, posterior pituitary gland and in the inner ear. Secretion of TFF3 is triggered by the presence of certain inflammation mediators and neurotransmitters.

Supplier: BioVendor

96 wells (1 kit) - ELISA is a competitive enzyme immunoassay for the quantitative measurement of 1,25(OH)₂ Vitamin D.

Supplier: BioVendor

96 wells (1 kit) - ELISA is a sandwich enzyme immunoassay for the quantitative measurement of Bone-specific Alkaline Phosphatase (BAP).

Supplier: BioVendor

96 wells (1 kit) - ELISA is a sandwich enzyme immunoassay for the quantitative measurement of N-MID Osteocalcin.

Supplier: BioVendor

The Purple-Jelley hyaluronan assay is a quantitative assay used to measure the quantity of hyaluronic acid in mammalian tissue.