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8256 results for "Bachem Americas"

8256 Results for: "Bachem Americas"

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Z-Arg-pNA·HCl

Supplier: Bachem Americas

Sequence: Z-Arg-pNA · HCl

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H-D-Ile-Phe-Lys-pNA Trifluoroacetate

Supplier: Bachem Americas

Patented by Chromogenix AB, Sweden (CH 622 285). A highly specific substrate for human plasmin. For rat plasmin, Heinemann et al. determined a Km of 18.3 μM. Also cleaved by transmembrane tryptase (TMT).

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N-Methoxysuccinyl-Ala-Ala-Pro-Val-p-nitroanilide

Supplier: Bachem Americas

Sequence: MeOSuc-Ala-Ala-Pro-Val-pNA

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Mca-(Ala⁷,Lys(Dnp)⁹)-Bradykinin Trifluoroacetate

Supplier: Bachem Americas

Substrate V, Mca-RPPGFSAFK(Dnp), is a very sensitive internally quenched fluorescent substrate for endothelin-converting enzyme-1 (ECE-1) a membrane-bound zinc metallopeptidase that is related to neprilysin in amino acid sequence. The kcat/Km value for the hydrolysis by ECE-1 was 1.9 x 10⁷ M⁻¹s⁻¹ and 1.7 x 10⁶ M⁻¹s⁻¹ for the hydrolysis by neprilysin. This FRET substrate was hydrolyzed rapidly by stromelysin 1 (MMP-3) with kcat/Km= 218000 M⁻¹s⁻¹ and very slowly by gelatinase B (MMP-9) (kcat/Km= 10100 M⁻¹s⁻¹). There was no hydrolysis by MMP-1 and MMP-2. Mca-RPPGFSAFK(Dnp) has also found use as substrate for insulin-degrading enzyme (IDE) and ACE2.

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Pepstatin A

Supplier: Bachem Americas

Pepstatin A (isovaleryl-pepstatin), a low molecular weight inhibitor of acid proteases, e.g. pepsin, renin, cathepsin D, and plasmepsin II. For the Plasmodium falciparum aspartyl protease plasmepsin II, Hill et al determined an IC₅₀ of 0.1 nM.

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(3S)-1-Chloro-3-tosylamido-7-amino-2-heptanone hydrochloride

Supplier: Bachem Americas

Sequence: Tos-Lys-chloromethylketone · HCl

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N-(p-Toluenesulfonyl)-L-phenylalanylchloromethylketone

Supplier: Bachem Americas

Sequence: Tos-Phe-chloromethylketone

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1,2-Dipalmitoyl-sn-glycero-3-phosphoethanolamine

Supplier: Bachem Americas

Sequence: 1,2-Dipalmitoyl-sn-glycero-3-phosphoethanolamine
Synonym(s): DPPE#L-β,γ-Dipalmitoyl-α-cephalin

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1,2-didodecanoyl-sn-glycerol

Supplier: Bachem Americas

Sequence: 1,2-Dilauroyl-sn-glycerol
Synonym(s): D-α,β-Dilaurin

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1,2-Distearoyllecithin

Supplier: Bachem Americas

Sequence: 1,2-Distearoyl-rac-glycero-3-phosphocholine
Synonym(s): DL-β,γ-Distearoyl-α-lecithin

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Fmoc-Ser(Glcnac(Ac)3-Beta-D)-Oh

Supplier: Bachem Americas

Bachem also offers derivatives of phosphoserine and sulfoserine.

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Pig Neuropeptide Y Trifluoroacetate

Supplier: Bachem Americas

1mg CAS: 83589-17-7 C190H287N55O57 FW: 4253.71 . Synonym: NPY (porcine)

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H-Phe-Phe-Phe-Phe-Phe-OH

Supplier: Bachem Americas

Pentaphenylalanine, FFFFF.

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H-Phe-Phe-Phe-OH

Supplier: Bachem Americas

FFF is a bitter-tasting peptide due to its hydrophobicity. As diphenylalanine, triphenylalanine forms ordered nanostructures.

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(Trp⁶)-LHRH Trifluoroacetate

Supplier: Bachem Americas

LHRH is also called Gonadotropin-Releasing Hormone (GnRH) or Luteinizing Hormone-Releasing Factor (LRF).

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beta-Neoendorphin

Supplier: Bachem Americas

For other opioid peptides see, the product families ‘Deltorphins and Dermorphins’, ‘Dynorphin, Analogs and Sequences, ‘Endorphins, MPF, Neoendorphins’, and ‘Opioid Peptides’.

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H-Ala-Ile-OH, Bachem

Supplier: Bachem Americas

A nanotube-forming dipeptide.

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H-Arg-Ile-OH acetate, Bachem

Supplier: Bachem Americas

1G CAS: 62632-70-6 C12H25N5O3 FW: 287.36

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H-Ala-Val-OH, Bachem

Supplier: Bachem Americas

Forms nanotubes as its retroanalog H-Val-Ala-OH.

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Cyclo(-Ala-Ala)

Supplier: Bachem Americas

Also known as dioxopiperazines, piperazine-2,5-diones or DKPs. Diketopiperazines may occur as by-products during peptide synthesis or during the degradation of peptides. These cyclic dipeptides have been detected as taste-modulating compounds in food, they often show biological activity. DKPs are valuable chiral synthons, employed e.g. in Schöllkopf's versatile bislactim ether approach. They also have found use as catalysts for enantioselective synthesis, e.g. in the asymmetric Strecker reaction. See also the TRH metabolite cyclo(-His-Pro), G-1745, and cyclo(-Asp-Phe), G-1695, the major degradation product of aspartame.

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(R)-2-Hydroxy-4-methylpentanoic acid

Supplier: Bachem Americas

Sequence: D-α-Hydroxyisocaproic acid

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Human PAR-2 (1-6) Trifluoroacetate, Bachem

Supplier: Bachem Americas

PAR peptides (TRAP peptides and thrombin receptor-like peptides) activate the proteinase-activated receptors PAR-1 to PAR-4.

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H-Tyr-Tyr-Tyr-OH

Supplier: Bachem Americas

The bitter taste of tri-tyrosine, YYY, is due to its marked hydrophobicity. Narai-Kanayama and Aso showed that Tyr-Tyr (G-3480) and Tyr-Tyr-Tyr efficiently inhibit angiotensin I-converting enzyme (ACE) from rabbit lung, their IC₅₀ values were 34 μM and 51 μM, respectively. These two tyrosine peptides exhibited a mix of competitive and noncompetitive inhibitions.

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TRH-betaNA

Supplier: Bachem Americas

A sensitive and highly specific substrate for a rapid assay of rat brain TRH-deamidating enzyme (prolyl endopeptidase). TRH-βNA is also hydrolyzed by another TRH-degrading enzyme, pyroglutamyl peptidase II (thyroliberinase), which seems to play a key role in terminating the biological activity of neuronally released TRH.

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(S)-2-amino-2,3-dimethylbutanoic acid

Supplier: Bachem Americas

Sequence: H-α-Me-Val-OH

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(R)-Methyl-2-amino-3-chloropropanoate hydrochloride

Supplier: Bachem Americas

Sequence: H-β-Chloro-Ala-OMe · HCl

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3-Iodo-L-tyrosine

Supplier: Bachem Americas

Sequence: H-3-Iodo-Tyr-OH

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H-D-Tyr(tBu)-allyl ester·HCl

Supplier: Bachem Americas

Sequence: H-D-Tyr(tBu)-allyl ester · HCl

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L-4-Cyanophenylalanine

Supplier: Bachem Americas

Sequence: H-4-Cyano-Phe-OH

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H-Pro-Ala-OH

Supplier: Bachem Americas

Substrate for human kidney prolinase (prolyl dipeptidase), used for monitoring the enzyme purification.

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