104372 Results for: "ALADDIN SCIENTIFIC"

Supplier: ALADDIN SCIENTIFIC

1-Acetylguanidine is a guanidine derivative.1-Acetylguanidine (N-Carbamimidoylacetamide) may be used in the synthesis of 1H-imidazol-2-amine derivatives. 1-Acetylguanidine may be used in the preparation of: 4-[5-(3-fluorophenyl)furan-2-yl]-2-acetylamino-5-methylimidazole novel series of amino-protected 6-alkyl-, 6-aryl-, 6-heteroaryl- and 5,6-fused-cycloalkane 4-trifluoromethyl-2-acetylaminopyrimidines new series of protected 6-alkyl- and 6-aryl-2-acetylamino-4(3H)-pyrimidinones 4-trifluoromethyl-6-(2,2-dimethoxyethyl)-2-acetylaminopyrimidine

Supplier: ALADDIN SCIENTIFIC

5-Acetyluracil ≥97%

Supplier: ALADDIN SCIENTIFIC

Store at Room Temperature. The product can be stored for up to 12 months.

Supplier: ALADDIN SCIENTIFIC

(1S,2R)-(+)-2-Amino-1,2-diphenylethanol can be used:· To prepare vanadium(V) Schiff base complexes, which are used as catalysts in the oxidation of sulfides and olefins. · To prepare chiral selectors, which are immobilized on aminated silica gel, applicable as chiral stationary phase in HPLC. · To immobilize on the frame of α-zirconium phosphate to yield layered zirconium phosphonates, which are used in the heterogeneous catalysis. · As a chiral auxiliary in the preparation of homopropargylic alcohols from aliphatic and aromatic aldehydes.

Supplier: ALADDIN SCIENTIFIC

1-((3-(4-Chlorophenethyl)-1,2,4-oxadiazol-5-yl)methyl)-7-methyl-1H-purin-6(7H)-one ≥98% (by HPLC), Moligand™

Supplier: ALADDIN SCIENTIFIC

β-Asp-Phe methyl ester ≥96%

Supplier: ALADDIN SCIENTIFIC

Agarose, high resolution DNase, RNase, NICKase, none detected

Supplier: ALADDIN SCIENTIFIC

2-Amino-6-methoxypyridine ≥97%

Supplier: ALADDIN SCIENTIFIC

(Acetonitrile)[(2-biphenyl)di-tert-butylphosphine]gold(I) hexafluoroantimonate ≥98%

Supplier: ALADDIN SCIENTIFIC

Application:5-Amino-3-methyl-isothiazole hydrochloride may be used in chemical synthesis studies.Used for pharmacological studies as a precursor for:1.MMP12 inhibitors2.Aurora kinase inhibitors3.N-Heterocyclic indolyl glyoxylamides as anticancer agents.

Supplier: ALADDIN SCIENTIFIC

9-Anthraceneboronic acid ≥99% (contains varying amounts of Anhydride)

Supplier: ALADDIN SCIENTIFIC

DL-Alanyl-DL-leucine ≥95%

Supplier: ALADDIN SCIENTIFIC

1-Amino-3,6,9,12,15,18,21,24-octaoxaheptacosan-27-oic acid ≥98%

Supplier: ALADDIN SCIENTIFIC

Acridine yellow G ≥90%

Supplier: ALADDIN SCIENTIFIC

9-Acetyl-3,6-diiodocarbazole ≥96%

Supplier: ALADDIN SCIENTIFIC

Azilsartan ≥98% (by HPLC), Moligand™

Supplier: ALADDIN SCIENTIFIC

2-Amino-4-(trifluoromethyl)pyridine ≥99%

Supplier: ALADDIN SCIENTIFIC

4-Amino-3-bromopyridine ≥98%

Supplier: ALADDIN SCIENTIFIC

AZD4547 is a novel selective FGFR inhibitor targeting FGFR1/2/3 with IC50 of 0.2 nM/2.5 nM/1.8 nM, weaker activity against FGFR4, VEGFR2(KDR), and little activity observed against IGFR, CDK2, and p38. Phase 2/3.A novel selective FGFR inhibitor targeting FGFR1, FGFR2, and FGFR3.

Supplier: ALADDIN SCIENTIFIC

2-Amino-5-fluorobenzonitrile ≥97%

Supplier: ALADDIN SCIENTIFIC

Product DescriptionDGAT-1 inhibitor A 922500 (A-922500) reduces serum triglyceride levels from baseline at all doses tested; however, this is only statistically significant at the 3 mg/kg dose, which lowers serum triglycerides by 53%. Similarly, the 3 mg/kg dose of A 922500 significantly reduces serum FFA concentrations by 55% and total cholesterol by 25%. DGAT-1 inhibition has no significant effect on body weight at any dose tested. Although A 922500 dpes not significantly affect LDL-cholesterol or HDL-cholesterol individually, the serum LDL/HDL-cholesterol ratio is significantly improved by A 922500 at 0.3 and 3 mg/kg. Similar to the dyslipidemic hamster, treatment with 3 mg/kg A 922500 significantly reduces serum triglyceride concentrations (39%). FFA levels significantly increase over the 14-day period in vehicle-treated animals. This increase is inhibited in a dose-dependent manner by A 922500 such that FFA concentrations are 32% lower after 14 days of treatment with the DGAT-1 inhibitor at 3 mg/kg, compared with the vehicle group (p < 0.05). HDL-cholesterol is significantly increased from baseline levels by A 922500 at 0.3 and 3 mg/kg; however, this is only significantly increased compared with vehicle at the 3 mg/kg dose. Body weight significantly increases over the 2-week period in vehicle-treated rats, and this is not affected by A 922500. LDL-cholesterol is significantly reduced in the vehicle treated group. DGAT-1 inhibition does not further reduce LDL-cholesterol and has no effect on total cholesterol.Product ApplicationA922500 has been used in the inhibition of diacylglycerol acyltransferase (DGAT) in epithelial human breast cancer cell line (MDA-MB-231), digitonin-permeabilized human cancer cells, human myotubes and macrophages.

Supplier: ALADDIN SCIENTIFIC

3-Aminopiperidin-2-one ≥98%

Supplier: ALADDIN SCIENTIFIC

6-Methoxyanthranilic acid ≥97%

Supplier: ALADDIN SCIENTIFIC

4-Amino-3-fluorobenzonitrile ≥98%

Supplier: ALADDIN SCIENTIFIC

β-D-Allose (β-D-Allose), a rare sugar member of the aldohexose family and a C3 epimer of glucose, is used as an inhibitor of fruiting body formation and sporulation in Myxococcus xanthus

Supplier: ALADDIN SCIENTIFIC

2-Aminonicotinamide ≥97%

Supplier: ALADDIN SCIENTIFIC

Ammonium hexachlororuthenate(IV) Ru 28.4% min

Supplier: ALADDIN SCIENTIFIC

1,5-Dihydroxy-9,10-anthraquinone ≥85%

Supplier: ALADDIN SCIENTIFIC

Apixaban is a highly selective, reversible inhibitor of Factor Xa with Ki of 0.08 nM and 0.17 nM in human and rabbit, respectively. Apixaban is in development for the prevention and treatment of various thromboembolic diseases.

Supplier: ALADDIN SCIENTIFIC

Ambrisentan is a selective ET type A receptor (ETAR) antagonist.