494 Results for: "3,5,5-trimethylhexanol"

Supplier: Novus Biologicals

The GPR1 Antibody from Novus Biologicals is a mouse polyclonal antibody to GPR1. This antibody reacts with human. The GPR1 Antibody has been validated for the following applications: Western Blot.

Supplier: Novus Biologicals

The SPSB3 Antibody from Novus Biologicals is a mouse polyclonal antibody to SPSB3. This antibody reacts with human. The SPSB3 Antibody has been validated for the following applications: Western Blot, ELISA, Immunocytochemistry / Immunofluorescence.

Supplier: Proteintech

OUTD7B is a member of the A20 family of the deubiquitinating cysteine proteases, which has deubiquitinating activity that is directed towards 'Lys-48' or 'Lys-63'-linked polyubiquitin chains. It plays a key role in the negative feedback regulation of NF-κB signaling in response to multiple stimuli and has been described as central gatekeeper in inflammation and immunity.

Supplier: Novus Biologicals

The G Protein alpha z Antibody from Novus Biologicals is a mouse polyclonal antibody to G Protein alpha z. This antibody reacts with human. The G Protein alpha z Antibody has been validated for the following applications: Western Blot.

Supplier: Novus Biologicals

The MBTPS1 Antibody (2E6.) from Novus Biologicals is a mouse monoclonal antibody to MBTPS1. This antibody reacts with human. The MBTPS1 Antibody (2E6.) has been validated for the following applications: ELISA, Immunocytochemistry / Immunofluorescence.

Supplier: Novus Biologicals

The AUF1 Antibody from Novus Biologicals is a rabbit polyclonal antibody to AUF1. This antibody reacts with human. The AUF1 Antibody has been validated for the following applications: Western Blot, Immunocytochemistry / Immunofluorescence.

Supplier: Novus Biologicals

The BAAT Antibody (1E4.) from Novus Biologicals is a mouse monoclonal antibody to BAAT. This antibody reacts with human. The BAAT Antibody (1E4.) has been validated for the following applications: Western Blot, ELISA.

Supplier: Novus Biologicals

The AUF1 Antibody from Novus Biologicals is a mouse polyclonal antibody to AUF1. This antibody reacts with human. The AUF1 Antibody has been validated for the following applications: Western Blot, Immunocytochemistry / Immunofluorescence.

Supplier: Novus Biologicals

The OR1I1 Antibody (1G6) from Novus Biologicals is a mouse monoclonal antibody to OR1I1. This antibody reacts with human. The OR1I1 Antibody (1G6) has been validated for the following applications: Western Blot, ELISA.

Supplier: Novus Biologicals

The Corneodesmosin Antibody (5B4) from Novus Biologicals is a mouse monoclonal antibody to Corneodesmosin. This antibody reacts with human. The Corneodesmosin Antibody (5B4) has been validated for the following applications: Western Blot, ELISA.

Supplier: Novus Biologicals

The Corneodesmosin Antibody (6F11) from Novus Biologicals is a mouse monoclonal antibody to Corneodesmosin. This antibody reacts with human. The Corneodesmosin Antibody (6F11) has been validated for the following applications: Western Blot, ELISA.

Supplier: Novus Biologicals

The BIN1 Antibody (2C7) from Novus Biologicals is a mouse monoclonal antibody to BIN1. This antibody reacts with human. The BIN1 Antibody (2C7) has been validated for the following applications: Western Blot, ELISA.

Supplier: Proteintech

GNAI2, also named as GNAI2B, belongs to the G-alpha family. G(i/o/t/z) subfamily. Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. The G(i) proteins are involved in hormonal regulation of adenylate cyclase: they inhibit the cyclase in response to beta-adrenergic stimuli. GNAI2 is 93% homolog to GNAI1, 94% to GNAI3, 85% to GNAT3, 82% to GNAT2.

Supplier: Proteintech

Hermansky-Pudlak syndrome 5 protein (HPS-5), also named Ruby-eye protien 2 homolog (Ru2), plays a role in organelle biogenesis associated with melanosomes, platelet dense granules, and lysosomes. This protein interacts with Hermansky-Pudlak syndrome 6 protein and may interact with the cytoplasmic domain of integrin, alpha-3. Mutations in this gene are associated with Hermansky-Pudlak syndrome type 5.

Supplier: Proteintech

Protein-serine/threonine and protein-tyrosine kinases (PSK and PTK) comprise two major classes of protein kinases. They provide a key switch dictating the dynamic nature and graded regulation of signal transduction pathway activities in cellular organization. DSTYK is a members of the RIP serine/threonine kinase family which involved in activation of NF-KB, JNK, and p38, and induction of apoptosis. This antibody is specific to DSTYK.

Supplier: Novus Biologicals

The HCLS1 Antibody (1A8) from Novus Biologicals is a mouse monoclonal antibody to HCLS1. This antibody reacts with human. The HCLS1 Antibody (1A8) has been validated for the following applications: Western Blot, ELISA, Immunohistochemistry-Paraffin, Proximity Ligation Assay, RNA Inhibition.

Supplier: Proteintech

WWP2(WW domain-containing protein 2) is also named as AIP2 and belongs to the NEDD4-like protein family. It functions as an E3 ubiquitin ligase for PTEN that plays a vital role in tumour-cell survival and is also involved in regulating transcription, embryonic stem-cell fate, cellular transport and T-cell activation processes.WWP2, which specifically interacted with ES cell-specific transcription factor Oct-4 and promoted its ubiquitination both in vitro and in vivo, is a ubiquitously expressed protein and exists in both cytoplasmic and nuclear compartments in ES cells.

Supplier: Prosci

Cytokine-mediated signal transduction in the JAK-STAT cascade requires the involvement of adaptor molecules. One such signal-transducing adaptor molecule contains an SH3 domain that is required for induction of MYC and cell growth. The protein encoded by this gene binds to the SH3 domain of the signal-transducing adaptor molecule, and plays a critical role in cytokine-mediated signaling for MYC induction and cell cycle progression. Multiple alternatively spliced transcript variants encoding the same protein isoform have been found for this gene.

Supplier: Novus Biologicals

The G protein alpha Inhibitor 2 Antibody (3G11) from Novus Biologicals is a mouse monoclonal antibody to G protein alpha Inhibitor 2. This antibody reacts with human. The G protein alpha Inhibitor 2 Antibody (3G11) has been validated for the following applications: Western Blot, ELISA, Proximity Ligation Assay.

Supplier: MCR Safety

Whether working in the rugged oil and gas industry or spending the day working near electrical hazards, stay safe and comfortable in MCR Safety's Flame Resistant (FR) Gear made with Max Comfort™ fabrics

Supplier: Proteintech

KIF3A is a subunit of Kinesin II that is essential for intraflagellar transport (IFT). It functions as the anterograde motor to deliver ciliary components to the tip where the axoneme is assembled. Disruption of KIF3A has been reported to block mammalian ciliogenesis. Recently KIF3A has been found to localize to the mother centriole and is required for centrioles organization. This antibody specifically recognizes the endogenous KIF3A protein in mouse embryonic fibroblasts (MEFs) but not in KIF3A-/- lysate. (23386061)

Supplier: Proteintech

CX3CR1, also known as GPR13, V28 and fractalkine receptor, belongs to the 7-transmembrane G protein-coupled receptor (GPCR) family. It is expressed on microglia, astrocytes, NK cells, monocytes/macrophages, and a subpopulation of T cells. CX3CR1 is the receptor for fractalkine (CX3CL1) and mediates both its adhesive and migratory functions. It also acts as coreceptor with CD4 for HIV-1 virus envelope protein (in vitro), and some variations in the gene of CX3CR1 lead to increased susceptibility to HIV-1 infection and rapid progression to AIDS. Defects in CX3CR1 are a cause of susceptibility to age-related macular degeneration type 12 (ARMD12).

Supplier: Proteintech

HOOK1, an orthologue of the Drosophila Hook protein, is a member of the microtubule-binding HOOK family of cytosolic coiled-coil proteins (HOOK1, HOOK2, HOOK3). These proteins contain conserved N-terminal domains, which attach to microtubules, and more divergent C-terminal domains, which mediate binding to organelles. HOOK1 is required for spermatid differentiation. It is probably involved in the positioning of the microtubules of the manchette and the flagellum in relation to the membrane skeleton. HOOK1 is a component of the FTS/Hook/FHIP complex which functions to promote vesicle trafficking and/or fusion via the HOPS (homotypic vesicular protein sorting) complex.

Supplier: MCR Safety

Whether working in the rugged oil and gas industry or spending the day working near electrical hazards, stay safe and comfortable in MCR Safety's Flame Resistant (FR) Gear made with Max Comfort™ fabrics

Supplier: Proteintech

PON1, also named as PON and K-45, belongs to the paraoxonase family. PON1 hydrolyzes the toxic metabolites of a variety of organophosphorus insecticides. It can capable of hydrolyzing a broad spectrum of organophosphate substrates and a number of aromatic carboxylic acid esters. PON1 may mediate an enzymatic protection of low density lipoproteins against oxidative modification and the consequent series of events leading to atheroma formation. For glycosylated, the MW of PON1 is migrated 42-45kd. 55kd is a dimmer of isoform CRA-b. The antibody has crss-reaction to PON2 and PON3.

Supplier: Prosci

E2A is a transcription factor that plays major roles in determining tissue-specific cell fate during embryogenesis, like muscle or early B-cell differentiation. Heterodimers between E2A and tissue-specific basic helix-loop-helix (bHLH) Dimers bind DNA on E-box motifs: 5'- CANNTG-3'. Binds to the kappa-E2 site in the kappa immunoglobulin gene enhancer. Deletions in E2A have been observed in a subset of pre-B-cell acute lymphoblastic leukemia (B-ALL) cases. Two alternatively spliced human isoforms have been described.

Supplier: Proteintech

Rab9 GTPase is required for the transport of mannose 6-phosphate receptors from endosomes to the trans-Golgi network in living cells, and in an in vitro system that reconstitutes this process. P40 is an effector of Rab9 that interacts preferentially with the active form of Rab9. p40 does not interact with Rab7 or K-Ras; it also fails to bind Rab9 when it is bound to GDI. The protein is found in cytosol, yet a significant fraction (~30%) is associated with cellular membranes. P40 is a very potent transport factor in that the pure, recombinant protein can stimulate, significantly, an in vitro transport assay that measures transport of mannose 6-phosphate receptors from endosomes to the trans-Golgi network.

Supplier: MCR Safety

Whether working in the rugged oil and gas industry or spending the day working near electrical hazards, stay safe and comfortable in MCR Safety's Flame Resistant (FR) Gear made with Max Comfort™ fabrics

Supplier: Proteintech

Aryl-hydrocarbon receptor nuclear translocator 2(ARNT2), is a member of the basic-helix-loop-helix-Per-Arnt-Sim (bHLH-PAS) superfamily of transcription factors. It specifically recognizes the xenobiotic response element(XRE). ARNT2 plays an important role in normal glucose handling in pancreatic beta cell function in humans and mice. ARNT2 proteins are dimeric partners for other PAS proteins such as HIF and SIM. ARNT2 and the other ARNT family members, e.g., ARNT, hypoxin inducible factor 1α (HIF1α), HIF2α, and aryl hydrocarbon receptor (AhR), are thought to function as heterodimers, and regulate the expression, and thereby the function, of many genes. Under hypoxic conditions, it complexes with hypoxia-inducible factor 1alpha in the nucleus and this complex binds to hypoxia-responsive elements in enhancers and promoters of oxygen-responsive genes. Modulation of ARNT2 in pancreatic beta cells affects glucose stimulated insulin secretion (GSIS). This antibody is a rabbit polyclonal antibody raised against residues near the C terminus of human ARNT2.

Supplier: Proteintech

SMAD2, also named as MADH2 and MADR2, belongs to the dwarfin/SMAD family, contains 1 MH1 (MAD homology 1) domain and 1 MH2 (MAD homology 2) domain. SMAD2 is a receptor-regulated SMAD(R-SMAD) that is an intracellular signal transducer and transcriptional modulator activated by TGF-beta (transforming growth factor) and activin type 1 receptor kinases. This protein may act as a tumor suppressor in colorectal carcinoma. It is phosphorylated on one or several of Thr-220, Ser-245, Ser-250, and Ser-255. In response to TGF-beta, It is phosphorylated on Ser-465/467 by TGF-beta and activin type 1 receptor kinases, and then able to interact with SMURF2, recruiting other proteins, such as SNON, for degradation. In response to decorin, the naturally occurring inhibitor of TGF-beta signaling, it is phosphorylated on Ser-240 by CaMK2. It is phosphorylated by MAPK3 upon EGF stimulation; which increases transcriptional activity and stability, and is blocked by calmodulin. In response to TGF-beta, it is ubiquitinated by NEDD4L, which promotes its degradation. In response to TGF-beta signaling, it is acetylated on Lys-19 by coactivators, which increases transcriptional activity. This antibody is a rabbit polyclonal antibody raised against residues near the N terminus of human SMAD2.