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Human Recombinant IL-17A (from E. coli)

Vial, 500 µg
Catalog # 77751-820
Supplier:   VWR International
Human Recombinant IL-17A (from E. coli)
Catalog # 77751-820
Supplier:  VWR International
CAS Number:  
Human Recombinant IL-17A (from E. coli)
Human Recombinant IL-17A (from E. coli)

Vial, 500 µg

Specifications
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Specifications
CAS Number:  
Price
$1,765.00
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Product Details & Documents

Interleukin 17A (IL-17A), also known as CTLA-8, is a member of the IL-17 family of proteins. IL-17A is a proinflammatory cytokine that is secreted by activated CD4+ and CD8+ T lymphocytes. IL-17A acts through its receptor, IL-17R, to promote increased cytokine and chemokine secretion. In turn, the cytokines and chemokines mediate the immunoregulatory function of IL-17A by promoting the proliferation, maturation, and chemoattraction of neutrophils to inflammatory sites.

  • High quality
  • Low endotoxin
  • Affordable

Elevated levels of IL-17A are associated with rheumatoid arthritis, airway inflammation, allograft rejection, inflammatory bowel disease, psoriasis, cancer, and multiple sclerosis. Human, mouse, and rat IL-17A show activity on mouse cells.

 : For research use only.

 

Specifications

Specifications

  • Pack type:
    Vial
  • Size:
    500 µg
  • Storage Conditions:
    –20 °C
  • Molecular Weight:
    15.7/31.3 kDa
  • Protease-free:
    N
  • Reconstitution Instructions:
    Sterile water at 0.1 mg/ml
  • Endotoxin Level:
    Low
  • Purity:
    ≥95%
  • Carrier-Free:
    Y
  • Source:
    E. coli
  • Nuclease-free:
    N
  • Biological Activity:
    Bioactivity assay: Production of IL-6 from mouse 3T3 cells; ED50 ≤10 ng/ml; Bioactivity ≥1.0×10⁵ units/mg
  • Protein/Peptide Type:
    Recombinant
  • Gene ID:
    Q16552
  • Formulation:
    0.1% trifluoroacetic acid (TFA)
  • Protein/Peptide Name:
    IL-17A
  • Endotoxin-free:
    N
  • Species:
    Human
  • Protein Function:
    Cytokine
  • Animal-Free:
    N
  • Tested Applications:
    Bioassay
  • Grade:
    RUO
  • Endotoxin Content:
    Endotoxin LAL (EU/µg) ≤0.1
  • Sequence:
    MIVKAGITIP RNPGCPNSED KNFPRTVMVN LNIHNRNTNT NPKRSSDYYN RSTSPWNLHR NEDPERYPSV IWEAKCRHLG CINADGNVDY HMNSVPIQQE ILVLRREPPH CPNSFRLEKI LVSVGCTCVT PIVHHVA
  • Cat. No.:
    77751-820
  • Shipping Temperature:
    RT
  • Protein Synonyms:
    IL-17|CTLA-8
  • Conjugation:
    Unconjugated

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