Human Recombinant PDGF-AB (from E. coli)
- Item requires temperature control for storage and delivery with additional fees. It's not eligible for return due to safety and quality concerns. Consider requirements before purchasing.
- Return Policy
Product Details & Documents
Platelet-derived growth factor (PDGF) is an important regulator of cell growth, proliferation, and angiogenesis. PDGF synthesis is induced by IL-1, IL-6, TNF-α, TGF-β and EGF signaling. PDGF functions as a mitogenic growth hormone on cells of mesenchymal lineage, such as smooth muscle and glial cells. PDGF is also stored in the alpha-granules of platelets and is released upon adherence to traumatized tissues.
- High quality
- Low endotoxin
- Affordable
PDGF is a dimeric glycoprotein formed by two A chains (AA), two B chains (BB), or as a heterodimer with an A and a B chain (AB). The PDGF dimer binds the cell surface receptor tyrosine kinases PDGFR-α and PDGFR-β.
Caution: For research use only.
Documents
VWR Cytokine and Growth Factors.pdf
Product Literature
Specifications
Specifications
- Pack type:Vial
- Size:500 µg
- Storage Conditions:–20 °C
- Molecular Weight:Alpha:14.4 kDa; Beta: 12.4 kDa; Total 26.8 kDa
- Protease-free:N
- Reconstitution Instructions:Sterile water at 0.1 mg/ml
- Endotoxin Level:Low
- Purity:≥95%
- Carrier-Free:Y
- Source:E. coli
- Nuclease-free:N
- Biological Activity:Bioactivity assay: NR6R-3T3 cell proliferation; ED50 ≤20 ng/ml; Bioactivity ≥5.0×10⁴ units/mg
- Protein/Peptide Type:Recombinant
- Gene ID:P04085/P01127
- Formulation:0.1% Trifluoroacetic Acid (TFA)
- Protein/Peptide Name:PDGF-AB
- Endotoxin-free:N
- Species:Human
- Protein Function:Cytokine
- Animal-Free:N
- Tested Applications:Bioassay
- Grade:RUO
- Endotoxin Content:Endotoxin LAL (EU/µg) ≤0.1
- Sequence:Alpha chain: MSIEEAVPAV CKTRTVIYEI PRSQVDPTSA NFLIWPPCVE VKRCTGCCNT SSVKCQPSRV HHRSVKVAKV EYVRKKPKLK EVQVRLEEHL ECACATTSLN PDYREEDTGR PRESGKKRKR KRLKPT Beta chain: MSLGSLTIAE PAMIAECKTR TEVFEISRRL IDRTNANFLV WPPCVEVQRC SGCCNNRNVQ CRPTQVQLRP VQVRKIEIVR KKPIFKKATV TLEDHLACKC ETVAAARPVT
- Cat. No.:77750-748
- Shipping Temperature:RT
- Protein Synonyms:GDGF|ODGF
- Conjugation:Unconjugated
Specifications
#: 21905-026
Supplier: Kimberly-Clark
#: 89039-656
Supplier: VWR International
#: 32934-078
Supplier: Kimberly-Clark