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Recombinant Murine Flt3-Ligand
Mouse Recombinant Flt3-Ligand (from E. coli)
Catalog # 10780-340
Supplier:  Peprotech
CAS Number:  
Mouse Recombinant Flt3-Ligand (from E. coli)
Catalog # 10780-340
Supplier:  Peprotech
Supplier Number:  250-31L-50UG
CAS Number:  

Specifications

  • Conjugation:
    Unconjugated
  • Protein Function:
    Cytokines and Growth Factors
  • Protein/Peptide Type:
    Recombinant
  • Source:
    E. coli
  • Species:
    Mouse
  • Size:
    50 μg
  • Storage Conditions:
    Store at –20 °C prior to reconstitution.
  • Endotoxin Content:
    >0.1 ng/μg
  • Biological Activity:
    Biological Activity tests can vary. Please refer to the Product CoA for information.
  • Form:
    Lyophilized
  • Gene ID:
    14256 P49772
  • Reconstitution Instructions:
    Reconstitution instructions can vary. Please refer to the product CoA for info.
  • Protease-free:
    Y
  • Protein Synonyms:
    Flt3L|Fms-related tyrosine kinase 3 ligand
  • Protein/Peptide Name:
    Flt3-Ligand
  • Purity:
    0.98
  • Molecular Weight:
    18.6 kDa
  • Sequence:
    MTPDCYFSHS PISSNFKVKF RELTDHLLKD YPVTVAVNLQ DEKHCKALWS LFLAQRWIEQ LKTVAGSKMQ TLLEDVNTEI HFVTSCTFQP LPECLRFVQT NISHLLKDTC TQLLALKPCI GKACQNFSRC LEVQCQPDSS TLLPPRSPIA LEATELPEPR PRQ
  • Endotoxin Level:
    Low
  • Formulation:
    Formulation can vary. Please refer to product CoA for information.
  • Shipping Temperature:
    Ambient
  • Cat. No.:
    10780-340
  • Origin:
    US
  • Supplier no.:
    250-31L-50UG

Specifications

About this item

Flt3-Ligand is a growth factor that regulates proliferation of early hematopoietic cells. Flt3-Ligand binds to cells expressing the tyrosine kinase receptor Flt3. Flt3-Ligand, by itself does not stimulate proliferation of early hematopoietic cells, but synergizes with other CSFs and interleukins to induce growth and differentiation. Unlike SCF, Flt3-Ligand exerts no activity on mast cells. Multiple isoforms of Flt3-Ligand have been identified. The predominant biologically active form is anchored to the cell surface as the extracellular domain of a transmembrane protein (209 a.a.). The membrane-bound isoform can be proteolytically cleaved to generate a biologically active soluble isoform. Recombinant Murine Flt3-Ligand is a soluble 18.6 kDa protein consisting of 163 amino acid residues.

Ordering information: For research use only. Not for use in diagnostic or therapeutic procedures.
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