Ac-DEVD-CHO
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Product Details & Documents
Caspase-3 inhibitor
Highly specific, potent and reversible inhibitor of caspase-3. Ki<1nM for purified caspase-3. IC50=0.2nM for PARP cleavage in cultured human osteosarcoma cell extracts. In contrast, the caspase-1 (ICE) specific inhibitor YVAD-CHO has a Ki=12µM for caspase-3 and IC50>10µM for PARP cleavage in osteosarcoma cell extracts. The DEVD sequence is based on PARP cleavage site Asp-216 for caspase-3.
Documents
Enzo Life Sciences Apoptosis Products
Product Literature
Specifications
Specifications
- Size:1 mg
- Cat. No.:89146-634
- Formulation:Lyophilized
- Reconstitution Instructions:Add 0.2ml DMSO per 1mg peptide. Shake well until all the contents are dissolved. This furnishes a 10mM solution of this material.
- Purity:>95% (HPLC)
- Protein/Peptide Name:Ac-DEVD-CHO
- Peptide Content:70-90%.
Specifications
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