Human Recombinant CCL2 (MCP-1) (from E. coli), Biotinylated
Supplier: CHEMOTACTICS, INC MS
Certificates
About this item
Functional biotin labeled human CCL2 chemokine with very low endotoxin levels.
- Extremely low endotoxin levels (<0.01 EU per 1 μg) Functional activity tested and validated For use in various streptavidin applications: Flow cytometry, microscopy, and other imaging techniques
Monocyte chemoattractant protein-1 (MCP-1) (CCL2) is produced by many cell types at sites of inflammation. It regulates chemotaxis and transendothielial migration of monocytes, as well as memory T cells and natural killer cells by interacting with their membrane surface receptor CCR2. MCP-1 has also been implicated in a number of disease states, such as rheumatoid arthritis, atherosclerosis, autoimmune diseases, tumor progression, and HIV infection.
Ordering information: Larger sizes available, please request a custom quote.
Delivery: Shipped lyophilized at room temperature.
Caution: For research use only, not for use in humans.
Specifications
- Conjugation:Biotin
- Protein Function:Chemokine
- Protein/Peptide Type:Recombinant
- Source:E. coli
- Species:Human
- Storage Conditions:Avoid repeated freeze-thaw cycles. 12 months from date of receipt, –20... –70 °C as supplied. ChemoTactics suggests using immediately after reconstitution. 1 month, –20...–70 °C under sterile conditions after reconstitution.
- Endotoxin Content:<0.01 EU per 1 μg of the protein by the LAL method
- Biological Activity:EC50 = 0.25 - 1.2 nM determined by Migration Assay of recombinant CCR2 containing cells
- Gene ID:Accession # P13500 (24-99)
- Reconstitution Instructions:Spin sample prior to reconstitution. Recommended concentration of 100 μg/ml in sterile water.
- Endotoxin-free:Y
- Carrier-Free:Y
- Protease-free:Y
- Protein Synonyms:HC11|MCAF|MCP1|MCP-1|SCYA2|GDCF-2|SMC-CF|HSMCR30
- Protein/Peptide Name:CCL2 (MCP-1)
- Purity:>97%
- Molecular Weight:11.09 kDa
- Endotoxin Level:Very low
- Formulation:Lyophilized pellet
- Shipping Temperature:RT
- Tested Applications:Migration assay
Specifications
Frequently Bought Together