Human Recombinant BDNF (from E. coli)
Supplier: VWR International
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About this item
Brain-derived neurotrophic factor (BDNF) is a nerve growth factor that binds two receptors, the low-affinity nerve growth factor receptor (LNGFR) and the tropomyosin receptor kinase B (TrkB), to support neuron growth and survival. BDNF expression in the hippocampus is essential for long-term memory storage and learning. Human, mouse, rat, and pig BDNF are cross-reactive.
High quality
- Low endotoxin
- Affordable
Caution:
For research use only.
Specifications
- Conjugation:Unconjugated
- Protein Function:Cytokine
- Protein/Peptide Type:Recombinant
- Source:E. coli
- Species:Human
- Storage Conditions:−20 °C
- Endotoxin Content:Endotoxin LAL (EU/µg) ≤0.1
- Biological Activity:Bioactivity assay: Proliferation of a neuroblastoma cell line stably expressing TrkB (BR6); ED₅₀ ≤40 ng/ml; Bioactivity ≥2.5×10⁴ units/mg
- Gene ID:P23560
- Reconstitution Instructions:Sterile water at 0.1 mg/ml
- Endotoxin-free:N
- Carrier-Free:Y
- Protease-free:N
- Animal-Free:Y
- Protein/Peptide Name:BDNF
- Purity:≥95%
- Molecular Weight:13.6/27.3 kDa
- Sequence:MHSDPARRGE LSVCDSISEW VTAADKKTAV DMSGGTVTVL EKVPVSKGQL KQYFYETKCN PMGYTKEGCR GIDKRHWNSQ CRTTQSYVRA LTMDSKKRIG WRFIRIDTSC VCTLTIKRGR
- Endotoxin Level:Low
- Formulation:0.1% Trifluoroacetic acid (TFA)
- Nuclease-free:N
- Grade:RUO
- Shipping Temperature:RT
- Tested Applications:Bioassay
Specifications
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