Mouse Recombinant M-CSF (from E. coli)

Supplier: VWR International

New Product

Certificates

Supplier: VWR International

New Product

About this item

Macrophage colony stimulating factor (M-CSF) is a hematopoietic growth factor that is widely produced by a variety of cells. M-CSF stimulates the proliferation and differentiation of hematopoietic stem cells into monocyte and macrophage cell types. M-CSF also acts through the colony stimulating factor 1 receptor (CSF1R) to modulate processes involved in immunology, bone metabolism, fertility, and pregnancy. Human M-CSF shows activity on mouse cells; however, mouse M-CSF shows no activity on human cells.

High quality Low endotoxin Lot-to-lot consistency Animal free Manufactured following GMP guidelines

Caution: For research use or further manufacturing only.

Specifications

Conjugation:
Unconjugated
Protein Function:
Cytokine
Protein/Peptide Type:
Recombinant
Source:
E. coli
Species:
Mouse
Storage Conditions:
–20 °C
Endotoxin Content:
Endotoxin LAL (EU/µg) ≤0.1
Biological Activity:
Bioactivity assay: NFS-60 cell proliferation; ED50 ≤10 ng/ml; Bioactivity ≥1.0×10⁵ units/mg
Gene ID:
P07141
Reconstitution Instructions:
Sterile water at 0.1 mg/ml
Endotoxin-free:
N
Carrier-Free:
Y
Protease-free:
N
Animal-Free:
Y
Protein Synonyms:
MGI-IM|CSF-1
Protein/Peptide Name:
M-CSF
Purity:
≥95%
Molecular Weight:
18.2/36.4
Sequence:
MKEVSEHCSH MIGNGHLKVL QQLIDSQMET SCQIAFEFVD QEQLDDPVCY LKKAFFLVQD IIDETMRFKD NTPNANATER LQELSNNLNS CFTKDYEEQN KACVRTFHET PLQLLEKIKN FFNETKNLLE KDWNIFTKNC NNSFAKCSSR DVVTKP
Endotoxin Level:
Low
Formulation:
10 mM Sodium phosphate, 50 mM sodium chloride, pH 7.5
Nuclease-free:
N
Grade:
RUO
Shipping Temperature:
RT