Human Recombinant IL-17F (from E. coli)

New Product

Human Recombinant IL-17F (from E. coli)

New Product

Interleukin 17F (IL-17F), a member of the IL-17 cytokine family, is secreted by activated CD4+ T cells and monocytes. IL-17F binds the IL-17 receptor related molecule, IL17RC, to promote the production of the interleukin 6 (IL-6), interleukin 8 (IL-8), and granulocyte macrophage colony-stimulating factor (GM-CSF) cytokines. IL-17F also functions to regulate matrix turnover rates, inhibit endothelial cell angiogenesis, and induce the endothelial cell expression of interleukin 2 (IL-2), monocyte chemoattractant protein-1 (MCP-1), and transforming growth factor beta 1 (TGF-b1).

High quality

Low endotoxin

Lot-to-lot consistency

Animal free

Manufactured following GMP guidelines

For research use or further manufacturing only.

Conjugation:
Unconjugated
Protein Function:
Cytokine
Protein/Peptide Type:
Recombinant
Source:
E. coli
Species:
Human
Storage Conditions:
–20 °C
Endotoxin Content:
Endotoxin LAL (EU/µg) ≤0.1
Biological Activity:
Bioactivity assay: Production of IL-6 from mouse NIH 3T3 cells; ED50 ≤100 ng/ml; Bioactivity ≥1.0×10⁴ units/mg
Gene ID:
Q96PD4
Reconstitution Instructions:
Sterile water at 0.1 mg/ml
Endotoxin-free:
N
Carrier-Free:
Y
Protease-free:
N
Animal-Free:
Y
Protein/Peptide Name:
IL-17F
Purity:
≥95%
Molecular Weight:
15.0/30.1
Sequence:
MRKIPKVGHT FFQKPESCPP VPGGSMKLDI GIINENQRVS MSRNIESRST SPWNYTVTWD PNRYPSEVVQ AQCRNLGCIN AQGKEDISMN SVPIQQETLV VRRKHQGCSV SFQLEKVLVT VGCTCVTPVI HHVQ
Endotoxin Level:
Low
Formulation:
0.1% Trifluoroacetic Acid (TFA)
Nuclease-free:
N
Grade:
RUO
Shipping Temperature:
RT