Human Recombinant GMCSF (from E. coli cells)

Supplier: VWR International

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Supplier: VWR International

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About this item

GM-CSF is a hematopoietic growth factor with the ability to form colonies of granulocytes and macrophages. Enhances the number of circulating white blood cells and function of neutrophils and monocytes. Regulates multiple functions via transcription factors in the differentiated cells, including cell survival, proliferation, and maturation. Generates in vitro murine and human DC populations from bone marrow precursors and blood monocytes, respectively.

High quality
Low endotoxin
Lot-to-lot consistency
Animal free
Manufactured following GMP guidelines

Human and mouse GM-CSF do not show cross-reactivity. The biological activity of CTGrade GMP interleukins and growth factors is standardized, where applicable, to WHO International standards, providing cell and gene therapy developers consistent, lot-to-lot biological activity and performance.

Host cell protein: ≤30 ng/ml, host cell DNA: ≤0.01 ng/ml, sterility testing: No growth, mycoplasma: Negative

Caution: For research use or further manufacturing only.

Specifications

Conjugation:
Unconjugated
Protein Function:
Cytokine
Protein/Peptide Type:
Recombinant
Source:
E. coli
Species:
Human
Storage Conditions:
At or below –20 °C
Endotoxin Content:
Endotoxin LAL (EU/µg) ≤0.05
Biological Activity:
Bioactivity assay: Proliferation of TF-1; ED50 ≤0.2 ng/ml; Bioactivity ≥1.6×10⁴ IU/µg
Gene ID:
P04141
Reconstitution Instructions:
Sterile water at 0.1 - 0.5 mg/ml
Endotoxin-free:
N
Carrier-Free:
Y
Protease-free:
N
Animal-Free:
Y
Protein Synonyms:
CSF-2|Pluripoietin-α|MGI-1GM
Protein/Peptide Name:
GMCSF
Purity:
≥98%
Molecular Weight:
14.6 kDa
Sequence:
MAPARSPSPS TQPWEHVNAI QEARRLLNLS RDTAAEMNET VEVISEMFDL QEPTCLQTRL ELYKQGLRGS LTKLKGPLTM MASHYKQHCP PTPETSCATQ IITFESFKEN LKDFLLVIPF DCWEPVQE
Endotoxin Level:
Low
Formulation:
10 mM sodium phosphate, pH 7.5
Nuclease-free:
N
Grade:
GMP
Shipping Temperature:
Ambient