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Human Recombinant PDGF-AB (from E. coli)

Human Recombinant PDGF-AB (from E. coli)

Supplier:   VWR International
Human Recombinant PDGF-AB (from E. coli)
Supplier:  VWR International
CertificatesHuman Recombinant PDGF-AB (from E. coli)

4 Options Available Below

  • Item requires temperature control for storage and delivery with additional fees. It's not eligible for return due to safety and quality concerns. Consider requirements before purchasing.
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Product Details & Documents

Platelet-derived growth factor (PDGF) is an important regulator of cell growth, proliferation, and angiogenesis. PDGF synthesis is induced by IL-1, IL-6, TNF-α, TGF-β and EGF signaling. PDGF functions as a mitogenic growth hormone on cells of mesenchymal lineage, such as smooth muscle and glial cells. PDGF is also stored in the alpha-granules of platelets and is released upon adherence to traumatized tissues.

  • High quality
  • Low endotoxin
  • Affordable

PDGF is a dimeric glycoprotein formed by two A chains (AA), two B chains (BB), or as a heterodimer with an A and a B chain (AB). The PDGF dimer binds the cell surface receptor tyrosine kinases PDGFR-α and PDGFR-β.

Caution: For research use only.

Documents

Specifications for Product Family

Specifications

Specifications

  • Catalog No:
  • 77750-686
  • 77750-688
  • 77750-710
  • 77750-748
  • Protein/Peptide Name:
  • PDGF-AB
  • PDGF-AB
  • PDGF-AB
  • PDGF-AB
  • Protein Synonyms:
  • GDGF|ODGF
  • GDGF|ODGF
  • GDGF|ODGF
  • GDGF|ODGF
  • Protein/Peptide Type:
  • Recombinant
  • Recombinant
  • Recombinant
  • Recombinant
  • Protein Function:
  • Cytokine
  • Cytokine
  • Cytokine
  • Cytokine
  • Species:
  • Human
  • Human
  • Human
  • Human
  • Source:
  • E. coli
  • E. coli
  • E. coli
  • E. coli
  • Conjugation:
  • Unconjugated
  • Unconjugated
  • Unconjugated
  • Unconjugated
  • Gene ID:
  • P04085/P01127
  • P04085/P01127
  • P04085/P01127
  • P04085/P01127
  • Sequence:
  • Alpha chain: MSIEEAVPAV CKTRTVIYEI PRSQVDPTSA NFLIWPPCVE VKRCTGCCNT SSVKCQPSRV HHRSVKVAKV EYVRKKPKLK EVQVRLEEHL ECACATTSLN PDYREEDTGR PRESGKKRKR KRLKPT Beta chain: MSLGSLTIAE PAMIAECKTR TEVFEISRRL IDRTNANFLV WPPCVEVQRC SGCCNNRNVQ CRPTQVQLRP VQVRKIEIVR KKPIFKKATV TLEDHLACKC ETVAAARPVT
  • Alpha chain: MSIEEAVPAV CKTRTVIYEI PRSQVDPTSA NFLIWPPCVE VKRCTGCCNT SSVKCQPSRV HHRSVKVAKV EYVRKKPKLK EVQVRLEEHL ECACATTSLN PDYREEDTGR PRESGKKRKR KRLKPT Beta chain: MSLGSLTIAE PAMIAECKTR TEVFEISRRL IDRTNANFLV WPPCVEVQRC SGCCNNRNVQ CRPTQVQLRP VQVRKIEIVR KKPIFKKATV TLEDHLACKC ETVAAARPVT
  • Alpha chain: MSIEEAVPAV CKTRTVIYEI PRSQVDPTSA NFLIWPPCVE VKRCTGCCNT SSVKCQPSRV HHRSVKVAKV EYVRKKPKLK EVQVRLEEHL ECACATTSLN PDYREEDTGR PRESGKKRKR KRLKPT Beta chain: MSLGSLTIAE PAMIAECKTR TEVFEISRRL IDRTNANFLV WPPCVEVQRC SGCCNNRNVQ CRPTQVQLRP VQVRKIEIVR KKPIFKKATV TLEDHLACKC ETVAAARPVT
  • Alpha chain: MSIEEAVPAV CKTRTVIYEI PRSQVDPTSA NFLIWPPCVE VKRCTGCCNT SSVKCQPSRV HHRSVKVAKV EYVRKKPKLK EVQVRLEEHL ECACATTSLN PDYREEDTGR PRESGKKRKR KRLKPT Beta chain: MSLGSLTIAE PAMIAECKTR TEVFEISRRL IDRTNANFLV WPPCVEVQRC SGCCNNRNVQ CRPTQVQLRP VQVRKIEIVR KKPIFKKATV TLEDHLACKC ETVAAARPVT
  • Protease-free:
  • N
  • N
  • N
  • N
  • Animal-Free:
  • N
  • N
  • N
  • N
  • Nuclease-free:
  • N
  • N
  • N
  • N
  • Carrier-Free:
  • Y
  • Y
  • Y
  • Y
  • Endotoxin-free:
  • N
  • N
  • N
  • N
  • Endotoxin Level:
  • Low
  • Low
  • Low
  • Low
  • Endotoxin Content:
  • Endotoxin LAL (EU/µg) ≤0.1
  • Endotoxin LAL (EU/µg) ≤0.1
  • Endotoxin LAL (EU/µg) ≤0.1
  • Endotoxin LAL (EU/µg) ≤0.1
  • Biological Activity:
  • Bioactivity assay: NR6R-3T3 cell proliferation; ED50 ≤20 ng/ml; Bioactivity ≥5.0×10⁴ units/mg
  • Bioactivity assay: NR6R-3T3 cell proliferation; ED50 ≤20 ng/ml; Bioactivity ≥5.0×10⁴ units/mg
  • Bioactivity assay: NR6R-3T3 cell proliferation; ED50 ≤20 ng/ml; Bioactivity ≥5.0×10⁴ units/mg
  • Bioactivity assay: NR6R-3T3 cell proliferation; ED50 ≤20 ng/ml; Bioactivity ≥5.0×10⁴ units/mg
  • Purity:
  • ≥95%
  • ≥95%
  • ≥95%
  • ≥95%
  • Grade:
  • RUO
  • RUO
  • RUO
  • RUO
  • Formulation:
  • 0.1% Trifluoroacetic Acid (TFA)
  • 0.1% Trifluoroacetic Acid (TFA)
  • 0.1% Trifluoroacetic Acid (TFA)
  • 0.1% Trifluoroacetic Acid (TFA)
  • Molecular Weight:
  • Alpha:14.4 kDa; Beta: 12.4 kDa; Total 26.8 kDa
  • Alpha:14.4 kDa; Beta: 12.4 kDa; Total 26.8 kDa
  • Alpha:14.4 kDa; Beta: 12.4 kDa; Total 26.8 kDa
  • Alpha:14.4 kDa; Beta: 12.4 kDa; Total 26.8 kDa
  • Reconstitution Instructions:
  • Sterile water at 0.1 mg/ml
  • Sterile water at 0.1 mg/ml
  • Sterile water at 0.1 mg/ml
  • Sterile water at 0.1 mg/ml
  • Storage Conditions:
  • –20 °C
  • –20 °C
  • –20 °C
  • –20 °C
  • Shipping Temperature:
  • RT
  • RT
  • RT
  • RT
  • Tested Applications:
  • Bioassay
  • Bioassay
  • Bioassay
  • Bioassay

Specifications

Product Family Options

Product Information

  • Pack type
    Size
    Availability
    Price
  • 77750-686
    Vial
    100 µg
    Log in for availability
    Log in for availability
    Each
    Each - $463.33
    $463.33
    Each
       $463.33
    Minimum order quantity is 1
    Item requires temperature control for storage and delivery with additional fees. It's not eligible for return due to safety and quality concerns. Consider requirements before purchasing.
    Specifications:
    More
    Specifications
    Cat. No.
    77750-686
    Protein/Peptide Name
    PDGF-AB
    Protein Synonyms
    GDGF|ODGF
    Protein/Peptide Type
    Recombinant
    Protein Function
    Cytokine
    Species
    Human
    Source
    E. coli
    Conjugation
    Unconjugated
    Gene ID
    P04085/P01127
    Sequence
    Alpha chain: MSIEEAVPAV CKTRTVIYEI PRSQVDPTSA NFLIWPPCVE VKRCTGCCNT SSVKCQPSRV HHRSVKVAKV EYVRKKPKLK EVQVRLEEHL ECACATTSLN PDYREEDTGR PRESGKKRKR KRLKPT Beta chain: MSLGSLTIAE PAMIAECKTR TEVFEISRRL IDRTNANFLV WPPCVEVQRC SGCCNNRNVQ CRPTQVQLRP VQVRKIEIVR KKPIFKKATV TLEDHLACKC ETVAAARPVT
    Protease-free
    N
    Animal-Free
    N
    Nuclease-free
    N
    Carrier-Free
    Y
    Endotoxin-free
    N
    Endotoxin Level
    Low
    Endotoxin Content
    Endotoxin LAL (EU/µg) ≤0.1
    Biological Activity
    Bioactivity assay: NR6R-3T3 cell proliferation; ED50 ≤20 ng/ml; Bioactivity ≥5.0×10⁴ units/mg
    Purity
    ≥95%
    Grade
    RUO
    Formulation
    0.1% Trifluoroacetic Acid (TFA)
    Molecular Weight
    Alpha:14.4 kDa; Beta: 12.4 kDa; Total 26.8 kDa
    Reconstitution Instructions
    Sterile water at 0.1 mg/ml
    Storage Conditions
    –20 °C
    Shipping Temperature
    RT
    Tested Applications
    Bioassay
  • 77750-688
    Vial
    10 µg
    Log in for availability
    Log in for availability
    Each
    Each - $163.33
    $163.33
    Each
       $163.33
    Minimum order quantity is 1
    Item requires temperature control for storage and delivery with additional fees. It's not eligible for return due to safety and quality concerns. Consider requirements before purchasing.
    Specifications:
    More
    Specifications
    Cat. No.
    77750-688
    Protein/Peptide Name
    PDGF-AB
    Protein Synonyms
    GDGF|ODGF
    Protein/Peptide Type
    Recombinant
    Protein Function
    Cytokine
    Species
    Human
    Source
    E. coli
    Conjugation
    Unconjugated
    Gene ID
    P04085/P01127
    Sequence
    Alpha chain: MSIEEAVPAV CKTRTVIYEI PRSQVDPTSA NFLIWPPCVE VKRCTGCCNT SSVKCQPSRV HHRSVKVAKV EYVRKKPKLK EVQVRLEEHL ECACATTSLN PDYREEDTGR PRESGKKRKR KRLKPT Beta chain: MSLGSLTIAE PAMIAECKTR TEVFEISRRL IDRTNANFLV WPPCVEVQRC SGCCNNRNVQ CRPTQVQLRP VQVRKIEIVR KKPIFKKATV TLEDHLACKC ETVAAARPVT
    Protease-free
    N
    Animal-Free
    N
    Nuclease-free
    N
    Carrier-Free
    Y
    Endotoxin-free
    N
    Endotoxin Level
    Low
    Endotoxin Content
    Endotoxin LAL (EU/µg) ≤0.1
    Biological Activity
    Bioactivity assay: NR6R-3T3 cell proliferation; ED50 ≤20 ng/ml; Bioactivity ≥5.0×10⁴ units/mg
    Purity
    ≥95%
    Grade
    RUO
    Formulation
    0.1% Trifluoroacetic Acid (TFA)
    Molecular Weight
    Alpha:14.4 kDa; Beta: 12.4 kDa; Total 26.8 kDa
    Reconstitution Instructions
    Sterile water at 0.1 mg/ml
    Storage Conditions
    –20 °C
    Shipping Temperature
    RT
    Tested Applications
    Bioassay
  • 77750-710
    Vial
    1 mg
    Log in for availability
    Log in for availability
    Each
    Each - $3,811.67
    $3,811.67
    Each
       $3,811.67
    Minimum order quantity is 1
    Item requires temperature control for storage and delivery with additional fees. It's not eligible for return due to safety and quality concerns. Consider requirements before purchasing.
    Specifications:
    More
    Specifications
    Cat. No.
    77750-710
    Protein/Peptide Name
    PDGF-AB
    Protein Synonyms
    GDGF|ODGF
    Protein/Peptide Type
    Recombinant
    Protein Function
    Cytokine
    Species
    Human
    Source
    E. coli
    Conjugation
    Unconjugated
    Gene ID
    P04085/P01127
    Sequence
    Alpha chain: MSIEEAVPAV CKTRTVIYEI PRSQVDPTSA NFLIWPPCVE VKRCTGCCNT SSVKCQPSRV HHRSVKVAKV EYVRKKPKLK EVQVRLEEHL ECACATTSLN PDYREEDTGR PRESGKKRKR KRLKPT Beta chain: MSLGSLTIAE PAMIAECKTR TEVFEISRRL IDRTNANFLV WPPCVEVQRC SGCCNNRNVQ CRPTQVQLRP VQVRKIEIVR KKPIFKKATV TLEDHLACKC ETVAAARPVT
    Protease-free
    N
    Animal-Free
    N
    Nuclease-free
    N
    Carrier-Free
    Y
    Endotoxin-free
    N
    Endotoxin Level
    Low
    Endotoxin Content
    Endotoxin LAL (EU/µg) ≤0.1
    Biological Activity
    Bioactivity assay: NR6R-3T3 cell proliferation; ED50 ≤20 ng/ml; Bioactivity ≥5.0×10⁴ units/mg
    Purity
    ≥95%
    Grade
    RUO
    Formulation
    0.1% Trifluoroacetic Acid (TFA)
    Molecular Weight
    Alpha:14.4 kDa; Beta: 12.4 kDa; Total 26.8 kDa
    Reconstitution Instructions
    Sterile water at 0.1 mg/ml
    Storage Conditions
    –20 °C
    Shipping Temperature
    RT
    Tested Applications
    Bioassay
  • 77750-748
    Vial
    500 µg
    Log in for availability
    Log in for availability
    Each
    Each - $2,286.67
    $2,286.67
    Each
       $2,286.67
    Minimum order quantity is 1
    Item requires temperature control for storage and delivery with additional fees. It's not eligible for return due to safety and quality concerns. Consider requirements before purchasing.
    Specifications:
    More
    Specifications
    Cat. No.
    77750-748
    Protein/Peptide Name
    PDGF-AB
    Protein Synonyms
    GDGF|ODGF
    Protein/Peptide Type
    Recombinant
    Protein Function
    Cytokine
    Species
    Human
    Source
    E. coli
    Conjugation
    Unconjugated
    Gene ID
    P04085/P01127
    Sequence
    Alpha chain: MSIEEAVPAV CKTRTVIYEI PRSQVDPTSA NFLIWPPCVE VKRCTGCCNT SSVKCQPSRV HHRSVKVAKV EYVRKKPKLK EVQVRLEEHL ECACATTSLN PDYREEDTGR PRESGKKRKR KRLKPT Beta chain: MSLGSLTIAE PAMIAECKTR TEVFEISRRL IDRTNANFLV WPPCVEVQRC SGCCNNRNVQ CRPTQVQLRP VQVRKIEIVR KKPIFKKATV TLEDHLACKC ETVAAARPVT
    Protease-free
    N
    Animal-Free
    N
    Nuclease-free
    N
    Carrier-Free
    Y
    Endotoxin-free
    N
    Endotoxin Level
    Low
    Endotoxin Content
    Endotoxin LAL (EU/µg) ≤0.1
    Biological Activity
    Bioactivity assay: NR6R-3T3 cell proliferation; ED50 ≤20 ng/ml; Bioactivity ≥5.0×10⁴ units/mg
    Purity
    ≥95%
    Grade
    RUO
    Formulation
    0.1% Trifluoroacetic Acid (TFA)
    Molecular Weight
    Alpha:14.4 kDa; Beta: 12.4 kDa; Total 26.8 kDa
    Reconstitution Instructions
    Sterile water at 0.1 mg/ml
    Storage Conditions
    –20 °C
    Shipping Temperature
    RT
    Tested Applications
    Bioassay
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