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Human Recombinant IL-17A (from E. coli)

Human Recombinant IL-17A (from E. coli)

Supplier:   VWR International
Human Recombinant IL-17A (from E. coli)
Supplier:  VWR International
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Human Recombinant IL-17A (from E. coli)

5 Options Available Below

  • Item requires temperature control for storage and delivery with additional fees. It's not eligible for return due to safety and quality concerns. Consider requirements before purchasing.
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Product Details & Documents

Interleukin 17A (IL-17A), also known as CTLA-8, is a member of the IL-17 family of proteins. IL-17A is a proinflammatory cytokine that is secreted by activated CD4+ and CD8+ T lymphocytes. IL-17A acts through its receptor, IL-17R, to promote increased cytokine and chemokine secretion. In turn, the cytokines and chemokines mediate the immunoregulatory function of IL-17A by promoting the proliferation, maturation, and chemoattraction of neutrophils to inflammatory sites.

  • High quality
  • Low endotoxin
  • Affordable

Elevated levels of IL-17A are associated with rheumatoid arthritis, airway inflammation, allograft rejection, inflammatory bowel disease, psoriasis, cancer, and multiple sclerosis. Human, mouse, and rat IL-17A show activity on mouse cells.

Caution: For research use only.

Documents

Specifications for Product Family

Specifications

Specifications

  • Catalog No:
  • 77751-814
  • 77751-816
  • 77751-818
  • 77751-820
  • 77751-822
  • Protein/Peptide Name:
  • IL-17A
  • IL-17A
  • IL-17A
  • IL-17A
  • IL-17A
  • Protein Synonyms:
  • IL-17|CTLA-8
  • IL-17|CTLA-8
  • IL-17|CTLA-8
  • IL-17|CTLA-8
  • IL-17|CTLA-8
  • Protein/Peptide Type:
  • Recombinant
  • Recombinant
  • Recombinant
  • Recombinant
  • Recombinant
  • Protein Function:
  • Cytokine
  • Cytokine
  • Cytokine
  • Cytokine
  • Cytokine
  • Species:
  • Human
  • Human
  • Human
  • Human
  • Human
  • Source:
  • E. coli
  • E. coli
  • E. coli
  • E. coli
  • E. coli
  • Conjugation:
  • Unconjugated
  • Unconjugated
  • Unconjugated
  • Unconjugated
  • Unconjugated
  • Gene ID:
  • Q16552
  • Q16552
  • Q16552
  • Q16552
  • Q16552
  • Sequence:
  • MIVKAGITIP RNPGCPNSED KNFPRTVMVN LNIHNRNTNT NPKRSSDYYN RSTSPWNLHR NEDPERYPSV IWEAKCRHLG CINADGNVDY HMNSVPIQQE ILVLRREPPH CPNSFRLEKI LVSVGCTCVT PIVHHVA
  • MIVKAGITIP RNPGCPNSED KNFPRTVMVN LNIHNRNTNT NPKRSSDYYN RSTSPWNLHR NEDPERYPSV IWEAKCRHLG CINADGNVDY HMNSVPIQQE ILVLRREPPH CPNSFRLEKI LVSVGCTCVT PIVHHVA
  • MIVKAGITIP RNPGCPNSED KNFPRTVMVN LNIHNRNTNT NPKRSSDYYN RSTSPWNLHR NEDPERYPSV IWEAKCRHLG CINADGNVDY HMNSVPIQQE ILVLRREPPH CPNSFRLEKI LVSVGCTCVT PIVHHVA
  • MIVKAGITIP RNPGCPNSED KNFPRTVMVN LNIHNRNTNT NPKRSSDYYN RSTSPWNLHR NEDPERYPSV IWEAKCRHLG CINADGNVDY HMNSVPIQQE ILVLRREPPH CPNSFRLEKI LVSVGCTCVT PIVHHVA
  • MIVKAGITIP RNPGCPNSED KNFPRTVMVN LNIHNRNTNT NPKRSSDYYN RSTSPWNLHR NEDPERYPSV IWEAKCRHLG CINADGNVDY HMNSVPIQQE ILVLRREPPH CPNSFRLEKI LVSVGCTCVT PIVHHVA
  • Protease-free:
  • N
  • N
  • N
  • N
  • N
  • Animal-Free:
  • N
  • N
  • N
  • N
  • N
  • Nuclease-free:
  • N
  • N
  • N
  • N
  • N
  • Carrier-Free:
  • Y
  • Y
  • Y
  • Y
  • Y
  • Endotoxin-free:
  • N
  • N
  • N
  • N
  • N
  • Endotoxin Level:
  • Low
  • Low
  • Low
  • Low
  • Low
  • Endotoxin Content:
  • Endotoxin LAL (EU/µg) ≤0.1
  • Endotoxin LAL (EU/µg) ≤0.1
  • Endotoxin LAL (EU/µg) ≤0.1
  • Endotoxin LAL (EU/µg) ≤0.1
  • Endotoxin LAL (EU/µg) ≤0.1
  • Biological Activity:
  • Bioactivity assay: Production of IL-6 from mouse 3T3 cells; ED50 ≤10 ng/ml; Bioactivity ≥1.0×10⁵ units/mg
  • Bioactivity assay: Production of IL-6 from mouse 3T3 cells; ED50 ≤10 ng/ml; Bioactivity ≥1.0×10⁵ units/mg
  • Bioactivity assay: Production of IL-6 from mouse 3T3 cells; ED50 ≤10 ng/ml; Bioactivity ≥1.0×10⁵ units/mg
  • Bioactivity assay: Production of IL-6 from mouse 3T3 cells; ED50 ≤10 ng/ml; Bioactivity ≥1.0×10⁵ units/mg
  • Bioactivity assay: Production of IL-6 from mouse 3T3 cells; ED50 ≤10 ng/ml; Bioactivity ≥1.0×10⁵ units/mg
  • Purity:
  • ≥95%
  • ≥95%
  • ≥95%
  • ≥95%
  • ≥95%
  • Grade:
  • RUO
  • RUO
  • RUO
  • RUO
  • RUO
  • Formulation:
  • 0.1% trifluoroacetic acid (TFA)
  • 0.1% trifluoroacetic acid (TFA)
  • 0.1% trifluoroacetic acid (TFA)
  • 0.1% trifluoroacetic acid (TFA)
  • 0.1% trifluoroacetic acid (TFA)
  • Molecular Weight:
  • 15.7/31.3 kDa
  • 15.7/31.3 kDa
  • 15.7/31.3 kDa
  • 15.7/31.3 kDa
  • 15.7/31.3 kDa
  • Reconstitution Instructions:
  • Sterile water at 0.1 mg/ml
  • Sterile water at 0.1 mg/ml
  • Sterile water at 0.1 mg/ml
  • Sterile water at 0.1 mg/ml
  • Sterile water at 0.1 mg/ml
  • Storage Conditions:
  • –20 °C
  • –20 °C
  • –20 °C
  • –20 °C
  • –20 °C
  • Shipping Temperature:
  • RT
  • RT
  • RT
  • RT
  • RT
  • Tested Applications:
  • Bioassay
  • Bioassay
  • Bioassay
  • Bioassay
  • Bioassay

Specifications

Product Family Options

Product Information

  • Pack type
    Size
    Availability
    Price
  • Vial
    100 µg
    Log in for availability
    Log in for availability
    Each
    Each - $410.00
    $410.00
    Each
       $410.00
    Minimum order quantity is 1

    Item requires temperature control for storage and delivery with additional fees. It's not eligible for return due to safety and quality concerns. Consider requirements before purchasing.
    Specifications:
    More
    Specifications
    Cat. No.
    77751-814
    Protein/Peptide Name
    IL-17A
    Protein Synonyms
    IL-17|CTLA-8
    Protein/Peptide Type
    Recombinant
    Protein Function
    Cytokine
    Species
    Human
    Source
    E. coli
    Conjugation
    Unconjugated
    Gene ID
    Q16552
    Sequence
    MIVKAGITIP RNPGCPNSED KNFPRTVMVN LNIHNRNTNT NPKRSSDYYN RSTSPWNLHR NEDPERYPSV IWEAKCRHLG CINADGNVDY HMNSVPIQQE ILVLRREPPH CPNSFRLEKI LVSVGCTCVT PIVHHVA
    Protease-free
    N
    Animal-Free
    N
    Nuclease-free
    N
    Carrier-Free
    Y
    Endotoxin-free
    N
    Endotoxin Level
    Low
    Endotoxin Content
    Endotoxin LAL (EU/µg) ≤0.1
    Biological Activity
    Bioactivity assay: Production of IL-6 from mouse 3T3 cells; ED50 ≤10 ng/ml; Bioactivity ≥1.0×10⁵ units/mg
    Purity
    ≥95%
    Grade
    RUO
    Formulation
    0.1% trifluoroacetic acid (TFA)
    Molecular Weight
    15.7/31.3 kDa
    Reconstitution Instructions
    Sterile water at 0.1 mg/ml
    Storage Conditions
    –20 °C
    Shipping Temperature
    RT
    Tested Applications
    Bioassay
  • Vial
    1 mg
    Log in for availability
    Log in for availability
    Each
    Each - $2,940.00
    $2,940.00
    Each
       $2,940.00
    Minimum order quantity is 1

    Item requires temperature control for storage and delivery with additional fees. It's not eligible for return due to safety and quality concerns. Consider requirements before purchasing.
    Specifications:
    More
    Specifications
    Cat. No.
    77751-816
    Protein/Peptide Name
    IL-17A
    Protein Synonyms
    IL-17|CTLA-8
    Protein/Peptide Type
    Recombinant
    Protein Function
    Cytokine
    Species
    Human
    Source
    E. coli
    Conjugation
    Unconjugated
    Gene ID
    Q16552
    Sequence
    MIVKAGITIP RNPGCPNSED KNFPRTVMVN LNIHNRNTNT NPKRSSDYYN RSTSPWNLHR NEDPERYPSV IWEAKCRHLG CINADGNVDY HMNSVPIQQE ILVLRREPPH CPNSFRLEKI LVSVGCTCVT PIVHHVA
    Protease-free
    N
    Animal-Free
    N
    Nuclease-free
    N
    Carrier-Free
    Y
    Endotoxin-free
    N
    Endotoxin Level
    Low
    Endotoxin Content
    Endotoxin LAL (EU/µg) ≤0.1
    Biological Activity
    Bioactivity assay: Production of IL-6 from mouse 3T3 cells; ED50 ≤10 ng/ml; Bioactivity ≥1.0×10⁵ units/mg
    Purity
    ≥95%
    Grade
    RUO
    Formulation
    0.1% trifluoroacetic acid (TFA)
    Molecular Weight
    15.7/31.3 kDa
    Reconstitution Instructions
    Sterile water at 0.1 mg/ml
    Storage Conditions
    –20 °C
    Shipping Temperature
    RT
    Tested Applications
    Bioassay
  • Vial
    25 µg
    Log in for availability
    Log in for availability
    Each
    Each - $163.33
    $163.33
    Each
       $163.33
    Minimum order quantity is 1

    Item requires temperature control for storage and delivery with additional fees. It's not eligible for return due to safety and quality concerns. Consider requirements before purchasing.
    Specifications:
    More
    Specifications
    Cat. No.
    77751-818
    Protein/Peptide Name
    IL-17A
    Protein Synonyms
    IL-17|CTLA-8
    Protein/Peptide Type
    Recombinant
    Protein Function
    Cytokine
    Species
    Human
    Source
    E. coli
    Conjugation
    Unconjugated
    Gene ID
    Q16552
    Sequence
    MIVKAGITIP RNPGCPNSED KNFPRTVMVN LNIHNRNTNT NPKRSSDYYN RSTSPWNLHR NEDPERYPSV IWEAKCRHLG CINADGNVDY HMNSVPIQQE ILVLRREPPH CPNSFRLEKI LVSVGCTCVT PIVHHVA
    Protease-free
    N
    Animal-Free
    N
    Nuclease-free
    N
    Carrier-Free
    Y
    Endotoxin-free
    N
    Endotoxin Level
    Low
    Endotoxin Content
    Endotoxin LAL (EU/µg) ≤0.1
    Biological Activity
    Bioactivity assay: Production of IL-6 from mouse 3T3 cells; ED50 ≤10 ng/ml; Bioactivity ≥1.0×10⁵ units/mg
    Purity
    ≥95%
    Grade
    RUO
    Formulation
    0.1% trifluoroacetic acid (TFA)
    Molecular Weight
    15.7/31.3 kDa
    Reconstitution Instructions
    Sterile water at 0.1 mg/ml
    Storage Conditions
    –20 °C
    Shipping Temperature
    RT
    Tested Applications
    Bioassay
  • Vial
    500 µg
    Log in for availability
    Log in for availability
    Each
    Each - $1,765.00
    $1,765.00
    Each
       $1,765.00
    Minimum order quantity is 1

    Item requires temperature control for storage and delivery with additional fees. It's not eligible for return due to safety and quality concerns. Consider requirements before purchasing.
    Specifications:
    More
    Specifications
    Cat. No.
    77751-820
    Protein/Peptide Name
    IL-17A
    Protein Synonyms
    IL-17|CTLA-8
    Protein/Peptide Type
    Recombinant
    Protein Function
    Cytokine
    Species
    Human
    Source
    E. coli
    Conjugation
    Unconjugated
    Gene ID
    Q16552
    Sequence
    MIVKAGITIP RNPGCPNSED KNFPRTVMVN LNIHNRNTNT NPKRSSDYYN RSTSPWNLHR NEDPERYPSV IWEAKCRHLG CINADGNVDY HMNSVPIQQE ILVLRREPPH CPNSFRLEKI LVSVGCTCVT PIVHHVA
    Protease-free
    N
    Animal-Free
    N
    Nuclease-free
    N
    Carrier-Free
    Y
    Endotoxin-free
    N
    Endotoxin Level
    Low
    Endotoxin Content
    Endotoxin LAL (EU/µg) ≤0.1
    Biological Activity
    Bioactivity assay: Production of IL-6 from mouse 3T3 cells; ED50 ≤10 ng/ml; Bioactivity ≥1.0×10⁵ units/mg
    Purity
    ≥95%
    Grade
    RUO
    Formulation
    0.1% trifluoroacetic acid (TFA)
    Molecular Weight
    15.7/31.3 kDa
    Reconstitution Instructions
    Sterile water at 0.1 mg/ml
    Storage Conditions
    –20 °C
    Shipping Temperature
    RT
    Tested Applications
    Bioassay
  • Vial
    5 µg
    Log in for availability
    Log in for availability
    Each
    Each - $65.00
    $65.00
    Each
       $65.00
    Minimum order quantity is 1

    Item requires temperature control for storage and delivery with additional fees. It's not eligible for return due to safety and quality concerns. Consider requirements before purchasing.
    Specifications:
    More
    Specifications
    Cat. No.
    77751-822
    Protein/Peptide Name
    IL-17A
    Protein Synonyms
    IL-17|CTLA-8
    Protein/Peptide Type
    Recombinant
    Protein Function
    Cytokine
    Species
    Human
    Source
    E. coli
    Conjugation
    Unconjugated
    Gene ID
    Q16552
    Sequence
    MIVKAGITIP RNPGCPNSED KNFPRTVMVN LNIHNRNTNT NPKRSSDYYN RSTSPWNLHR NEDPERYPSV IWEAKCRHLG CINADGNVDY HMNSVPIQQE ILVLRREPPH CPNSFRLEKI LVSVGCTCVT PIVHHVA
    Protease-free
    N
    Animal-Free
    N
    Nuclease-free
    N
    Carrier-Free
    Y
    Endotoxin-free
    N
    Endotoxin Level
    Low
    Endotoxin Content
    Endotoxin LAL (EU/µg) ≤0.1
    Biological Activity
    Bioactivity assay: Production of IL-6 from mouse 3T3 cells; ED50 ≤10 ng/ml; Bioactivity ≥1.0×10⁵ units/mg
    Purity
    ≥95%
    Grade
    RUO
    Formulation
    0.1% trifluoroacetic acid (TFA)
    Molecular Weight
    15.7/31.3 kDa
    Reconstitution Instructions
    Sterile water at 0.1 mg/ml
    Storage Conditions
    –20 °C
    Shipping Temperature
    RT
    Tested Applications
    Bioassay
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