Order Entry
United States
ContactUsLinkComponent
PRIME-XV NK Cell CDM
PRIME-XV NK Cell CDM
  77975-348
New Product
 :  
undefined
PRIME-XV NK Cell CDM
  77975-348
 :  91215-1L
New Product
 :  

Some Products May Appear Restricted

To ensure a smooth and speedy checkout, please log in to your account. Some items may show as restricted simply because you're not logged in.

If you do not have an account, you can register using our registration webform (https://www.avantorsciences.com/us/en/login/register)

 

If you're still seeing restrictions after logging in, certain products—like chemicals or medical devices—require additional account verification steps to be able to place an order. Some items may additionally require a specific license or customer documentation;  additional documentation will be requested for these items prior to shipment. 

 

  • Media Format:
    Liquid
  • Pack type:
    Bottle
  • Size:
    1 L
  • Calcium:
    No
  • Magnesium:
    No
  • HEPES:
    No
  • Sodium bicarbonate:
    No
  • Sodium pyruvate:
    No
  • Phenol red:
    No
  • Stable glutamine:
    No
  • L-Glutamine:
    No
  • Glucose level:
    Without
  • Media Base:
    Proprietary Mixture (serum-free/chemically-defined)
  • Shelf life:
    18

 

 

Chemically defined, animal component-free medium for natural killer (NK) and NKT cell expansion optimized to deliver cell growth while maintaining NK and NKT cell functionality and potency.

  • Chemically defined, animal component-free formula

    Does not contain antibiotics or phenol red

PRIME-XV NK Cell CDM is the first commercially-available, chemically defined, and animal component-free medium for the ex vivo expansion of NK and NKT cells. Designed for use in NK and NKT cell-based immunotherapy research and translational applications, this advanced formulation delivers growth while maintaining NK and NKT cell functionality and potency - without the need for serum supplementation. Designed and manufactured to facilitate transfer from research to clinic. Supported by robust raw material controls and supply chain management.

Application:

Supports robust cell expansion and viability in heterogeneous PBMC culture enriched for CD56+ cells
Supports expansion of NK cells when supplemented with IL-2, IL-12, IL-18, and IL-21
Supports NKT cell expansion when supplemented with IL-2
Maintains high NK and NKT cytotoxic capability

 : FDA, Federal, and State registered - cGMP-compliant manufacture; EN ISO 13485:2016 certified; MDSAP certified; Extensive QC testing including functionality, sterility (USP <71>), and endotoxin (USP <85>); Drug Master Files (DMFs) filed with the FDA – available upon request.