BalanCD CHO Growth A is a chemically-defined, animal component-free growth medium designed to increase process yields of antibodies and recombinant proteins in Chinese Hamster Ovary (CHO) cells. This formulation was developed using FUJIFILM Irvine Scientific’s rational culture media design strategy to achieve enhanced performance of growth and production in batch cultures.

• Designed to maximize CHO cell growth, viability, and productivity at every development step and at any scale
• Thoughtfully balances key nutrients with an emphasis on maintaining protein quality
• Flexibly supports a range of CHO cell lines
• Pair with BalanCD CHO feed four for maximum productivity of high producing cell lines

BalanCD CHO Growth A is provided without L-Glutamine to extend shelf life. The recommended L-Glutamine concentration to add is 4 to 8 mM (20 to 40 ml/L). The medium should be used without L-Glutamine if the GS selection system is being used. Glucose should be monitored during culture, additional supplementation may be required. BalanCD CHO Growth A has been designed without Hypoxanthine and Thymidine for use with the dihydrofolate reductase (dhfr) and other selection systems. The medium contains no protein hydrolysates or any other undefined components. This medium contains no antibiotics or antimycotics.