L(+)-Histidine USP, Multi-Compendial

White Crystalline solid.

: L-3-Imidazol-4-ylalanine, (S)-(+)-Histidine, (S)-2-Amino-3-(4-imidazolyl)propionic acid, H-His-OH, NSC 137773, L-Histidine

:71-00-1
:C₆H₉N₃O₂
:MFCD00064315
:155.16 g/mol
:13,04741
:272…273 °C
:1.44 g/cm³ (20 °C)
:Management of Change (MOC) category = R
:Ambient
:200-745-3

White Crystalline solid.

: L-3-Imidazol-4-ylalanine, (S)-(+)-Histidine, (S)-2-Amino-3-(4-imidazolyl)propionic acid, H-His-OH, NSC 137773, L-Histidine

:71-00-1
:C₆H₉N₃O₂
:MFCD00064315
:155.16 g/mol
:13,04741
:272…273 °C
:1.44 g/cm³ (20 °C)
:Management of Change (MOC) category = R
:Ambient
:200-745-3

Documents

Product specification

USP - Assay (C₆H₉N₃O₂) (dried basis):
98.5 - 101.5 %
USP - Identification:
Passes Test
USP - Specific Rotation [Å]²⁵ ^D (+):
12.6 - 14.0 Degree
USP - pH:
7.0 - 8.5
USP - Loss on Drying at 105°C:
≤ 0.2 %
USP - Residue on Ignition:
≤ 0.4 %
USP - Chloride (Cl):
≤ 0.05 %
USP - Sulfate (SO₄):
≤ 0.03 %
USP - Iron (Fe):
≤ 0.003 %
USP - Related Compounds - Individual Impurities:
≤ 0.5 %
USP - Related Compounds - Total Impurities:
≤ 2.0 %
EP/BP - Assay (C₆H₉N₃O₂) (dried basis):
98.5 - 101.0 %
EP/BP - Identification A:
Passes Test
EP/BP - Identification B:
Passes Test
EP/BP - Appearance of Solution:
Passes Test
EP/BP - Specific Rotation [Å]²º^D (+):
11.4 - 12.4 Degree
EP/BP-Ninhydrin-Positive Substances-Each:
≤ 0.2 %
EP/BP-Ninhydrin-Positive Substances-Total Impurities:
≤ 0.5 %
EP/BP - Chloride (Cl):
≤ 200 ppm
EP/BP - Sulfate (SO₄):
≤ 300 ppm
EP/BP - Ammonium (NH₄):
≤ 0.02 %
EP/BP - Iron (Fe):
≤ 10 ppm
EP/BP - Loss on Drying:
≤ 0.5 %
EP/BP - Ash (sulfated):
≤ 0.1 %
JP - Assay (C6H9N3O2) (dried basis):
99.0 - 101.0 %
JP - Ammonium (NH₄):
≤ 0.02 %
JP - Chloride (Cl):
≤ 0.021 %
JP - Clarity and Color of Solution:
Passes Test
JP - Heavy Metals (as Pb):
≤ 10 ppm
JP - Iron (Fe):
≤ 10 ppm
JP - Identification:
Passes Test
JP - Loss on Drying at 105°C:
≤ 0.30 %
JP- Optical Rotation [Å]²º^D (+):
11.8 - 12.8 Degree
JP - Related Substances:
Passes Test
JP - pH:
7.0 - 8.5
JP - Residue on Ignition:
≤ 0.10 %
JP - Sulfate (SO₄):
≤ 0.028 %

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