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Sepharose™ CL-4B Phenyl Hydrophobic Interaction Chromatography Media, Cytiva
Sepharose™ CL-4B Phenyl Hydrophobic Interaction Chromatography Media, Cytiva
Catalog # 95016-996
Supplier:  Cytiva
Product available on GSA Advantage®
CAS Number:  
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Sepharose™ CL-4B Phenyl Hydrophobic Interaction Chromatography Media, Cytiva
Catalog # 95016-996
Supplier:  Cytiva
Supplier Number:  17-0810-01
Product available on GSA Advantage®
CAS Number:  

Specifications

  • Particle Size:
    90 µm
  • Description:
    Phenyl Sepharose™ CL-4B
  • Size:
    200 mL
  • Environmentally Preferable:
  • pH Range:
    3 - 12
  • Matrix:
    Cross-linked agarose, 4%, spherical
  • Ligand:
    Phenyl
  • Storage Temperature:
    4 - 30 °C
  • Binding Capacity:
    HSA (Mr 68 000) 15-20 mg/ml drained resin, ß-lactoglobulin (Mr 18 000) 3-5 mg/ml drained resin
  • Ligand Density:
    40 μmole/ml drained medium
  • Description:
    Phenyl Sepharose™ CL-4B
  • Flow Rate:
    150 cm/h
  • Cat. No.:
    95016-996
  • Type:
    Liquid
  • Supplier no.:
    17-0810-01

Specifications

About this item

Octyl-Sepharose™ CL-4B is a well-proven medium for hydrophobic interaction chromatography (HIC). Octyl immobilised on 4% cross-linked agarose.

  • Phenyl immobilized on 4% cross-linked agarose
  • Aromatic ligand
  • Stable in all commonly used aqueous buffers and additives such as 8 M urea and 6 M guanidine hydrochloride
  • Negligible volume variation due to changes in pH or ionic strength

Octyl Sepharose® CL-4B and Phenyl Sepharose® CL-4B are covalently coupled to a cross-linked 4% agarose matrix by ether linkage, resulting in hydrophobic gels with minimal leakage and no ionic properties.

Octyl Sepharose® 4 Fast Flow is another aliphatic media that provides different and complimentary selectivity. It too is made of agarose beads derivatized via uncharged, chemically stable ether linkages.

Octyl Sepharose® CL-4B and Phenyl Sepharose® CL-4B are covalently coupled to a cross-linked 4% agarose matrix by ether linkage, resulting in hydrophobic gels with minimal leakage and no ionic properties.

Phenyl Sepharose® 6 Fast Flow is available with low or high levels of phenyl substitution differing in selectivity, efficiency, and binding capacity. Both low and high sub media are made of highly cross-linked agarose beads derivatized with phenyl groups via uncharged, chemically stable ether linkages.