This assay has high sensitivity and excellent specificity for detecting Rat SPD (Surfactant Associated Protein D). The assay range is from 7.8 to 500 pg/ml (Sandwich kit) with a sensitivity of 2.6 pg/ml. There is no detectable cross to reactivity with other relevant proteins. Activity loss rate and accelerated stability test ect have been conducted to guarantee the best performance of the products after long storage and delivery.

• High sensitivity and specificity
• Perfect reproducibility and consistency across batches
• Quality control with three-level inspections
• Wide range of targets/species available
• Intra-Assay: CV <10%, Inter-Assay: CV <12%

Surfactant protein D (SP-D) belongs to the collectin family. These proteins are oligomeric proteins composed of carbohydrate-recognition domains(CRD)attached to collagenous regions.Collectins are structurally similar to the ficolins although they make use of different CRD structures: C-type lectin domain for the collectins. The lung is the major site of synthesis of SP-D, where the molecules are produced and secreted onto the epithelial surface by alveolar type II cells and unciliated bronchial epithelial cells. SP-D is also found in different epithelial cells of the gastrointestinal tract and in epithelial cells of various exocrine glands. SP-D is an important factor in the pulmonary anti-microbial defense. The anti-microbial defense mechanisms of SP-D are direct opsonization, neutralization and agglutination.