This assay has high sensitivity and excellent specificity for detecting Human IL10 (Interleukin 10). The assay range is from 1.56 to 100 pg/ml (Sandwich kit) with a sensitivity of 0.64 pg/ml. There is no detectable cross-reactivity with other relevant proteins. Activity loss rate and accelerated stability test ect have been conducted to guarantee the best performance of the products after long storage and delivery.

• High sensitivity and specificity
• Perfect reproducibility and consistency across batches
• Quality control with three-level inspections
• Wide range of targets/species available
• Intra-Assay: CV <10%, Inter-Assay: CV <12%

Interleukin-10 is a small protein known as a cytokine that functions as an important regulator of the immune system.  Although IL-10 is known to have many different roles in the immune system, its two major activities include inhibition of cytokine production by macrophages and inhibition of the accessory functions of macrophages during T cell activation. The effects of these actions cause IL-10 to play mainly an anti-inflammatory role in the immune system. IL-10 was originally known as the cytokine synthesis inhibiting factor (CSIF), and the discovery of this protein was based on its biological activity. IL-10 is mainly produced by the Th2 subset of CD4+ helper cells.  However, it is also produced by some activated B cells, some Th1 cells, activated macrophages, and some nonhematopoietic sources.