- Antibody Type:Primary
- Antigen Name:Mannose Receptor C Type 1
- Antigen Symbol:MRC1
- Clonality:Polyclonal
- Conjugation:Unconjugated
- Host:Rabbit
- ImmunoChemistry:Yes
- ImmunoPrecipitation:Yes
- Isotype:IgG
- Reactivity:Mouse
- Western Blot:Yes
- Size:200 µl
- Cross Adsorption:No
- Form:Liquid
- Gene ID:17533
- Antigen Synonyms:CD206|C-type lectin domain family 13 member D-like|CLEC13D|MRC1L1|CLEC13DL|Macrophage mannose receptor 1-like protein 1
- Amino Acid Number:225 - 492
- UniProtKB:Q61830
- Storage Buffer:0.01 M PBS, pH 7.4, containing 0.05% Proclin-300, 50% glycerol
- Molecular Weight:34 kDa
- Storage Temperature:Store at 2...8 °C for frequent use, −20 °C for 24 months. Avoid repeated freeze-thaw cycles.
- Concentration:0.5 mg/ml (for reference only)
- Shipping Temperature:Shipped on blue ice at 4 °C
- Immunogen:Recombinant MRC1 (Leu225~Ser492)
- Purification:Antigen-specific affinity chromatography followed by Protein A affinity chromatography
- Cat. No.:MSPP-PAB542MU1
- Packaging:Vial
Polyclonal Antibody to Mannose Receptor C Type 1 (MRC1), derived from recombinant MRC1 (Leu225~Ser492), is reactive with Mouse.
- High specificity, affinity, and purity
- Extensive validation and batch-to-batch consistency
- Diverse range of conjugated and custom options
- Comprehensive validation data and documentation
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The mannose receptor found on macrophages and on endothelial cells of the liver is the only known example of a C-type lectin that contains multiple C-type CRDs. One function of the receptor is to bind high-mannose structures on the surface of potentially pathogenic viruses, bacteria, and fungi, so that they can be neutralized by phagocytic engulfment., Kim et al. characterized the gene for the human macrophage mannose receptor (MRC1) by isolation of clones covering the entire coding region. MRC1 was demonstrated to be divided into 30 exons. The first 3 exons encode the signal sequence, the NH2-terminal cysteine-rich domain, and the fibronectin type II repeat, while the final exon encodes the transmembrane anchor and the cytoplasmic tail.
Type: Primary
Antigen: MRC1
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Mouse