Specifications
- Antibody Type:Primary
- Antigen Name:Myxovirus Resistance 1
- Antigen Symbol:MX1
- Clonality:Monoclonal
- Clone:C4
- Conjugation:Unconjugated
- Host:Mouse
- ImmunoChemistry:Yes
- Isotype:IgG2b kappa
- Reactivity:Human
- Western Blot:Yes
- Size:200 µl
- Cross Adsorption:No
- Form:Liquid
- Gene ID:4599
- Antigen Synonyms:MX|MxA|Interferon-regulated resistance GTP-binding protein MxA|Interferon-Inducible Protein p78|IFI-78K|IFI78
- Amino Acid Number:80 - 342
- UniProtKB:P20591
- Storage Buffer:0.01 M PBS, pH 7.4, containing 0.05% Proclin-300, 50% glycerol
- Molecular Weight:34 kDa
- Storage Temperature:Store at 2...8 °C for frequent use, −20 °C for 24 months. Avoid repeated freeze-thaw cycles.
- Concentration:1 mg/ml (for reference only)
- Shipping Temperature:Shipped on blue ice at 4 °C
- Immunogen:Recombinant MX1 (Ser80~Leu342)
- Purification:Protein A + Protein G affinity chromatography
- Cat. No.:MSPP-ML763HU21
- Packaging:Vial
Specifications
About this item
Monoclonal Antibody to Myxovirus Resistance 1 (MX1), derived from recombinant MX1 (Ser80~Leu342), is reactive with Human.
- High specificity, affinity, and purity
- Extensive validation and batch-to-batch consistency
- Diverse range of conjugated and custom options
- Comprehensive validation data and documentation
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MxA is a downstream target of FAC and is the first genetic marker to be identified among multiple FA complementation groups. FA subtypes may converge onto a final common pathway, which is intimately related to the interferon signaling mechanism. Constitutive activity of this pathway may explain a number of the phenotypic features of FA, particularly the pathogenesis of bone marrow failure.In mouse, the interferon-inducible Mx protein is responsible for a specific antiviral state against influenza virus infection. The protein encoded by this gene is similar to the mouse protein as determined by its antigenic relatedness, induction conditions, physicochemical properties, and amino acid analysis. This cytoplasmic protein is a member of both the dynamin family and the family of large GTPases.
Type: Primary
Antigen: MX1
Clonality: Monoclonal
Clone: C4
Conjugation: Unconjugated
Epitope:
Host: Mouse
Isotype: IgG2b kappa
Reactivity: Human