- Antibody Type:Primary
- Antigen Name:Beta Actin
- Antigen Symbol:ACTB
- Clonality:Monoclonal
- Clone:C5
- Conjugation:Unconjugated
- Host:Mouse
- ImmunoChemistry:Yes
- ImmunoPrecipitation:Yes
- Isotype:IgG2b kappa
- Reactivity:Pig,Rabbit,Human,Bovine,Dog,Rat,Mouse
- Western Blot:Yes
- Size:200 µl
- Cross Adsorption:No
- Form:Liquid
- Gene ID:60
- Antigen Synonyms:Actin, cytoplasmic 1, N-terminally processed|PS1TP5BP1|Actin Beta|ACT-B|Actin, cytoplasmic 1
- Amino Acid Number:1 - 375
- UniProtKB:P60709
- Storage Buffer:0.01 M PBS, pH 7.4, containing 0.05% Proclin-300, 50% glycerol
- Molecular Weight:44 kDa
- Storage Temperature:Store at 2...8 °C for frequent use, –20 ℃ for 24 months. Avoid repeated freeze-thaw cycles.
- Concentration:1 mg/ml (for reference only)
- Shipping Temperature:Shipped on blue ice at 4 °C.
- Immunogen:Recombinant ACTB (Met1~Phe375)
- Purification:Protein A + Protein G affinity chromatography
- Cat. No.:MSPP-MAB340MI2
- Packaging:Vial
Monoclonal Antibody to Beta Actin (ACTB), derived from recombinant ACTB (Met1~Phe375), is reactive with Human/Mouse/Rat/Dog/Pig/Bovine/Rabbit.
- High specificity, affinity, and purity
- Extensive validation and batch-to-batch consistency
- Diverse range of conjugated and custom options
- Comprehensive validation data and documentation
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Beta-actin (gene name ACTB) is one of the two no nmuscle cytoskeletal actins. Actins are highly conserved proteins that are involved in cell motility, structure and integrity. Alpha actins are a major constituent of the contractile apparatus. In a neoplastic cell line resulting from treatment of cultured human diploid fibroblasts with a chemical mutagen, Leavitt et al. (1982) observed a mutant form of beta actin. Toyama and Toyama (1984) isolated and characterized lines of KB cells resistant to cytochalasin B. They found that one resistant line had an alteration in beta-actin. Such cells bound less cytochalasin B than did parental KB cells. The authors suggested that the primary site of action of cytochalasin B on cell motility processes is beta-actin.
Type: Primary
Antigen: ACTB
Clonality: Monoclonal
Clone: C5
Conjugation: Unconjugated
Epitope:
Host: Mouse
Isotype: IgG2b Kappa
Reactivity: Human, Mouse, Rat, Dog, Pig, Bovine, Rabbit