Specifications
- Antibody Type:Primary
- Antigen Name:Osteocrin
- Antigen Symbol:OSTN
- Clonality:Polyclonal
- Conjugation:Unconjugated
- Host:Rabbit
- ImmunoChemistry:Yes
- ImmunoPrecipitation:Yes
- Isotype:IgG
- Reactivity:Mouse
- Western Blot:Yes
- Size:200 µl
- Cross Adsorption:No
- Form:Liquid
- Gene ID:239790
- Antigen Synonyms:Musclin
- Amino Acid Number:26 - 130
- UniProtKB:P61364
- Storage Buffer:0.01 M PBS, pH 7.4, containing 0.05% Proclin-300, 50% glycerol
- Molecular Weight:42 kDa
- Storage Temperature:Store at 2...8 °C for frequent use, −20 °C for 24 months. Avoid repeated freeze-thaw cycles.
- Concentration:0.5 mg/ml (for reference only)
- Shipping Temperature:Shipped on blue ice at 4 °C
- Immunogen:Recombinant OSTN(Phe26~Gly130)
- Purification:Antigen-specific affinity chromatography followed by Protein A affinity chromatography
- Cat. No.:MSPP-PAH492MU1
- Packaging:Vial
Specifications
About this item
Polyclonal Antibody to Osteocrin (OSTN), derived from recombinant OSTN(Phe26~Gly130), is reactive with Mouse.
- High specificity, affinity, and purity
- Extensive validation and batch-to-batch consistency
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OSTN encodes a deduced mature protein of 133 amino acids with a predicted molecular mass of approximately 11.4 kD. The human and mouse OSTN proteins share 74% sequence identity. Both contain a signal peptide and 2 predicted cleavage sites, KKKR and KKR, which are similar to those found in peptide hormone precursors. OSTN is evolutionarily conserved, with highest sequence conservation at the C terminus. Immunofluorescence Mutagenesis experiments demonstrated that the 5-kD band results from cleavage at the KKKR site. Northern blot analysis of mouse tissues detected bone-specific Ostn expression, but RT-PCR detected very low expression in muscle, kidney, testis, and heart. mouse Ostn expression is highest in embryos and neonates, peaking at postnatal day 4 and decreasing steadily with age.
Type: Primary
Antigen: OSTN
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Mouse