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Specifications
- Antibody Type:Primary
- Antigen Name:Immunoglobulin Superfamily Containing Leucine Rich Repeat Protein
- Antigen Symbol:ISLR
- Clonality:Monoclonal
- Clone:C3
- Conjugation:Unconjugated
- Host:Mouse
- ImmunoChemistry:Yes
- Isotype:IgG1 kappa
- Reactivity:Human
- Western Blot:Yes
- Size:200 µl
- Environmentally Preferable:
- Cross Adsorption:No
- Form:Liquid
- Gene ID:3671
- Amino Acid Number:19 - 428
- UniProtKB:O14498
- Storage Buffer:0.01 M PBS, pH 7.4, containing 0.05% Proclin-300, 50% glycerol
- Molecular Weight:48 kDa
- Storage Temperature:Store at 2...8 °C for frequent use, −20 °C for 24 months. Avoid repeated freeze-thaw cycles.
- Concentration:1 mg/ml (for reference only)
- Shipping Temperature:Shipped on blue ice at 4 °C
- Immunogen:Recombinant ISLR(Cys19~Phe428)
- Purification:Protein A + Protein G affinity chromatography
- Cat. No.:MSPP-MH781HU21
- Packaging:Vial
Specifications
About this item
Monoclonal Antibody to Immunoglobulin Superfamily Containing Leucine Rich Repeat Protein (ISLR), derived from recombinant ISLR(Cys19~Phe428), is reactive with Human.
- High specificity, affinity, and purity
- Extensive validation and batch-to-batch consistency
- Diverse range of conjugated and custom options
- Comprehensive validation data and documentation
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Nagasawa et al. (1997) isolated a cDNA for a novel human protein containing both a leucine-rich repeat (LRR) and an immunoglobulin (Ig)-like domain. ISLR was referred to as ISLR for 'immunoglobulin superfamily containing LRR.' The predicted protein comprises 428 amino acids and contains a hydrophobic N-terminal 18-amino acid putative signal peptide. Despite the variety of their functions, all members of the Ig superfamily are involved in adhesion or binding to other proteins in solution or at the cell surface. Therefore it is possible that the ISLR protein may also interact with other proteins or cells. On Northern blot analysis, the authors found a 2.4-kb ISLR transcript in various human tissues, including retina, heart, skeletal muscle, prostate, ovary, small intestine, thyroid, adrenal cortex, testis, stomach, and spinal cord, as well as fetal lung and fetal kidney.
Type: Primary
Antigen: ISLR
Clonality: Monoclonal
Clone: C3
Conjugation: Unconjugated
Epitope:
Host: Mouse
Isotype: IgG1 Kappa
Reactivity: Human