Specifications
- Antibody Type:Primary
- Antigen Name:Toll Like Receptor 3
- Antigen Symbol:TLR3
- Clonality:Polyclonal
- Conjugation:Unconjugated
- Host:Rabbit
- ImmunoChemistry:Yes
- ImmunoPrecipitation:Yes
- Isotype:IgG
- Reactivity:Rat,Mouse
- Western Blot:Yes
- Size:200 µl
- Cross Adsorption:No
- Form:Liquid
- Gene ID:142980
- Antigen Synonyms:CD283
- Amino Acid Number:574 - 713
- UniProtKB:Q99MB1
- Storage Buffer:PBS, pH 7.4, containing 0.02% NaN₃, 50% glycerol
- Molecular Weight:15 kDa
- Storage Temperature:Store at 2...8 °C for frequent use, −20 °C for 24 months. Avoid repeated freeze-thaw cycles.
- Concentration:1 mg/ml (for reference only)
- Shipping Temperature:Shipped on blue ice at 4 °C
- Immunogen:Recombinant TLR3(Gly574~Met713)
- Purification:Antigen-specific affinity chromatography followed by Protein A affinity chromatography
- Cat. No.:MSPP-PAB989MU1
- Packaging:Vial
Specifications
About this item
Polyclonal Antibody to Toll Like Receptor 3 (TLR3), derived from recombinant TLR3(Gly574~Met713), is reactive with Mouse/Rat.
- High specificity, affinity, and purity
- Extensive validation and batch-to-batch consistency
- Diverse range of conjugated and custom options
- Comprehensive validation data and documentation
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TLR 3 is a member of the Toll-like receptor family of pattern recognition receptors of the innate immune system. Discovered in 2001,TLR3 recognizes double-stranded RNA, a form of genetic information carried by some viruses such as reoviruses. Upon recognition, TLR 3 induces the activation of NF-kB to increase production of type I interferons which signal other cells to increase their antiviral defenses.,Double-stranded RNA is also recognised by the cytoplasmic receptors RIG-I and MDA-5.The structure of TLR3 was reported in June 2005 by researchers at The Scripps Research Institute. TLR3 forms a large horseshoe shape that contacts with a neighboring horseshoe, forming a 'dimer' of two horseshoes.
Type: Primary
Antigen: TLR3
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Mouse;Rat