Assay-specific Crystal Flex Probes and primers for the detection of TP53 mutations and its Positive Control. TP53 (drop-off V272-A276/G280-R283) Crystal Digital PCR® Assay is a 10X assay designed to detect and quantify mutations between V272-A276 or G280-R283 of the TP53 gene using the Ruby Chip. TP53 is pivotal in regulating cell divisison, thus an important tumor suppressor gene.

• Ready-to-use assay reagents to detect multiple targets in a single reaction
• Crystal Flex Probe detection chemistry for flexible assay configuration
• Same set of crystal universal reporters to detect any target in different assays

Wet lab tested
Compatibility: Nio™ Digital PCR, Prism6, Prism3, ruby chip
Channels: Blue, green
Required reagents: Crystal universal reporter 3 and naica® PCR MIX 10X
Target: TP53 V272-A276 and G280-R283