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Specifications
- Antigen Name:Alpha-Tubulin (Acetyl K40)
- Clonality:Monoclonal
- Clone:TEU318
- Host:Mouse
- Isotype:IgG1
- Reactivity:Other,Human,Rat,Mouse
- Size:100 µg
- Gene ID:7846
- Cat. No.:MSPP-100-0753
Specifications
About this item
Mouse monoclonal IgG1 antibody against human, mouse, rat acetylated alpha-tubulin (acetyl K40).
- Airway cells
- Epithelial cells
The TEU318 antibody reacts with the acetylated form of alpha-tubulin, which is a 55 kDa protein. In eukaryotic cells, alpha- and beta-tubulins associate to form heterodimers and are the key building blocks of microtubules. These microtubules are filamentous, cylinder-like cytoskeletal structural support elements of eukaryotic cells. The stability of these microtubules can be altered by post-translational modifications, such as the acetylation of alpha-tubulin. Acetyl groups can be added to Lys40 of alpha-tubulin by acetyltransferase alpha-Tat1 (Mec-17), and this post-translational modification can aid in stabilizing the overall microtubule structure. Research indicates that acetylated tubulin may play a critical role in the differentiation of microtubule structure and function.
Type: Anti-Alpha-Tubulin (Acetyl K40) Mouse Monoclonal Antibody [clone: TEU318]
Antigen: Alpha-Tubulin (Acetyl K40)
Clonality: Monoclonal
Clone: TEU318
Conjugation:
Epitope:
Host: Mouse
Isotype: IgG1
Reactivity: Human, Mouse, Other, Rat