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Specifications
- Antigen Name:SSEA-5
- Clonality:Monoclonal
- Clone:8E11
- Conjugation:PE (Phycoerythrin)
- Host:Mouse
- Isotype:IgG1 kappa
- Reactivity:Human
- Size:25 Tests
- Environmentally Preferable:
- Cat. No.:MSPP-60063PE1
Specifications
About this item
Mouse monoclonal IgG1 antibody against human SSEA-5, PE-conjugated.
- Pluripotent stem cells
The 8e11 antibody reacts with stage-specific embryonic antigen-5 (SSEA-5), a terminal H type-1 glycan (Fuc1-2Galβ1-3GlcNAcβ1) expressed on the surface of cells in the inner cell mass of the human blastocyst during embryogenesis, and on undifferentiated human embryonic stem (ES) and induced pluripotent stem (iPS) cells. Expression of SSEA-5 is rapidly down-regulated upon cellular differentiation. The 8e11 antibody can be used in conjunction with other pluripotency surface markers such as CD9 and CD90, or CD50 and CD200, to sort and remove undifferentiated teratoma-forming cells from incompletely differentiated stem cell cultures.
Type:
Antigen: SSEA-5
Clonality: Monoclonal
Clone: 8E11
Conjugation: PE
Epitope:
Host: Mouse
Isotype: IgG1 kappa
Reactivity: Human