Animal origin-free, stabilized, feeder-free maintenance medium for human ES and iPS cells.

Reduce risk and obtain more high-quality cells in your human pluripotent stem cell-derived (hPSC) cell therapy development with TeSR™-AOF, manufactured under relevant cGMPs. With no materials of animal or human origin to the secondary level of manufacturing, enjoy more straightforward traceability and enhanced viral safety compared to media that are only animal origin-free to the primary level of manufacturing. Use TeSR™-AOF to consistently culture viral-safe, high-quality PSCs on a schedule that works for you - with whatever cell lines you choose. To enhance cell quality attributes, particularly during restricted feeds, critical medium components have been stabilised, including fibroblast growth factor 2 (FGF2; also known as basic FGF [bFGF]).

As a result, TeSR™-AOF allows for both daily and restricted feeding schedules while maintaining cell quality and equivalent performance. TeSR™-AOF is compatible with a variety of culture matrices, including Corning® Matrigel® hESC-qualified matrix, Vitronectin XF™, and CellAdhere™ Laminin-521. No materials of animal or human origin are used in the manufacture of this medium or its components, to at least the secondary level of manufacturing. Each lot of TeSR™-AOF 20X Supplement that is used to prepare complete TeSR™-AOF medium is performance-tested in a culture assay using human pluripotent stem cells. TeSR™-AOF is manufactured under relevant cGMPs, ensuring the highest quality and consistency for reproducible results.