Human Recombinant HLA-A*03:01&B2M&gp100 (MHC-HM463)

Supplier: KACTUSBIO INC. MS

Certificates

Supplier: KACTUSBIO INC. MS

About this item

Quality validated and reproducible proteins provided at very competitive pricing.

Best quality
Reproducible supply
Functionally validated
Lowest price

Immunization against the ALLAVGATK peptide may occur in Melanoma patients and that the immunogenicity of this peptide is similar to that of the majority of Melanoma differentiation antigens defined to date. Therefore, the use of ALLAVGATK in active immunotherapy for HLA-A3 Melanoma patients, for whom no other immunogenic peptide has been so far described, remains a distinct possibility, providing that patients treated in vivo with this peptide develop a better in vitro response than already demonstrated for HLA-A2 epitopes generated from this same antigenic protein.

Certifications: ISO 13485.

Delivery: One to two days.

Packaging: Recyclable.

Some Products May Appear Restricted

To ensure a smooth and speedy checkout, please log in to your account. Some items may show as restricted simply because you're not logged in.

If you do not have an account, you can register using our registration webform (https://www.avantorsciences.com/us/en/login/register)

If you're still seeing restrictions after logging in, certain products—like chemicals or medical devices—require additional account verification steps to be able to place an order. Some items may additionally require a specific license or customer documentation; additional documentation will be requested for these items prior to shipment.

Specifications

Protein/Peptide Type:
Recombinant
Source:
HEK293 cells
Species:
Human
Tag sequence:
C-His-Avi
Storage Conditions:
–20 to –80 ℃ for 12 months as supplied from date of receipt. –80 ℃ for 3 - 6 months after reconstitution. 2 - 8 ℃ for 2 - 7 days after reconstitution. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Endotoxin Content:
Less than 1 EU per μg by the LAL method.
Gene ID:
NP_002107.3(HLA-A*03:01)&P61769(B2M)&ALLAVGATK
Reconstitution Instructions:
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
Endotoxin-free:
Y
Carrier-Free:
Y
Animal-Free:
N
Protein Synonyms:
HLA-A*03:01&B2M&gp100 (ALLAVGATK) Monomer
Protein/Peptide Name:
HLA-A*03:01&B2M&gp100
Purity:
<95% as determined by Tris-Bis PAGE; <95% as determined by HPLC
Molecular Weight:
The protein has a predicted MW of 50.15 kDa. Due to glycosylation, the protein migrates to 51 - 60 kDa based on Tris-Bis PAGE result.
Sequence:
Gly25-Thr305(HLA-A*03:01), Ile21-Met119(B2M) and ALLAVGATK peptide
Endotoxin Level:
Less than 1 EU per μg by the LAL method.
Formulation:
Lyophilized from 0.22 μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Shipping Temperature:
Shipped at ambient temperature.
Tested Applications:
SDS-Page, HPLC