Human Recombinant HLA-A*11:01&B2M&KRAS G12V, Biotin (MHC-HM422B)
Supplier: KACTUSBIO INC. MS
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About this item
Quality validated and reproducible proteins provided at very competitive pricing.
- Best quality
- Reproducible supply
- Functionally validated
- Lowest price
Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) is the most commonly mutated oncogene in human cancer. The developments of many cancers depend on sustained expression and signaling of KRAS, which makes KRAS a high-priority therapeutic target. The virtual screening approach to discover novel KRAS inhibitors and synthetic lethality interactors of KRAS are discussed in detail.
Certifications: ISO 13485.
Delivery: One to two days.
Packaging: Recyclable.
Specifications
- Conjugation:Biotin
- Protein/Peptide Type:Recombinant
- Source:HEK293 cells
- Species:Human
- Tag sequence:C-His-Avi
- Storage Conditions:–20 to –80 ℃ for 12 months as supplied from date of receipt. –80 ℃ for 3 - 6 months after reconstitution. 2 - 8 ℃ for 2 - 7 days after reconstitution. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- Endotoxin Content:Less than 1 EU per μg by the LAL method.
- Gene ID:AAV53343.1(HLA-A*11:01)&P61769(B2M)&VVGAVGVGK
- Reconstitution Instructions:Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
- Endotoxin-free:Y
- Carrier-Free:Y
- Animal-Free:N
- Protein Synonyms:KI-RAS|KRAS2|KRAS1|K-RAS2B|NS3|K-RAS4B|NS|RASK2|HLA-A*11:01&B2M&KRAS G12V (VVGAVGVGK) Monomer|C-K-RAS|K-Ras 2|K-RAS4A|K-RAS2A|MHC|RALD|KRAS|GTPase Kras|CFC2
- Protein/Peptide Name:HLA-A*11:01&B2M&KRAS G12V
- Purity:<95% as determined by Tris-Bis PAGE; <95% as determined by HPLC
- Molecular Weight:The protein has a predicted MW of 50.2 kDa. Due to glycosylation, the protein migrates to 56 - 65 kDa based on Tris-Bis PAGE result.
- Sequence:Gly25-Thr305(HLA-A*11:01),Ile21-Met119(B2M) and VVGAVGVGK peptide
- Endotoxin Level:Less than 1 EU per μg by the LAL method.
- Formulation:Lyophilized from 0.22 μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
- Shipping Temperature:Shipped at ambient temperature.
- Tested Applications:SDS-Page, HPLC
Specifications
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