About this item
Quality validated and reproducible proteins provided at very competitive pricing.
- Best quality
- Reproducible supply
- Functionally validated
- Lowest price
p53 is a tumor suppressor protein. Under stressful conditions, p53 tightly regulates cell growth by promoting apoptosis and DNA repair. When p53 becomes mutated, it loses its function, resulting in abnormal cell proliferation and tumor progression. Depending on the p53 mutation, it has been shown to form aggregates leading to negative gain of function of the protein. p53 mutant associated aggregation has been observed in several cancer tissues and has been shown to promote tumor growth.
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Supplier: VWR International
Supplier: VWR International
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