Empore™ SPE disk plates are the ideal sample preparation format for LC/MS and other high throughput applications

Bonded silica sorbents are commonly used for the solid phase extraction of analytes from complex sample matrices. A variety of functional groups, such as octadecyl (C18), octyl (C8), and ethyl (C2), can be bonded to the silica surface to provide nonpolar interactions. Mixed phase cation (MPC) sorbent is a silica-based particle that has been bonded with both a reversed phase group (octyl) and a strong cation exchange group (benzene sulfonic acid).

This mixed phase chemistry, in which two primary modes of attraction are present, allows for a more efficient and selective extraction compared to traditional reversed phase techniques. Neutral and ionized analytes can be simultaneously extracted from a complex mixture and eluted as separate fractions. Universal resin is used for high retention of a wide range of analytes, reducing method development time and facilitating a generic approach to sample preparation.

Disk diameter is 5.5 mm. Filter plates are designed for protein precipitation and are compatible with a variety of collection formats, including 96-well automation. The use of these plates eliminates the need for centrifugation.