Kupffer cells are the resident macrophages in the human liver. Like Tempo-iPhago™ (macrophages are white blood cells that capture and kill microorganisms), Kupffer cells display innate immune functions protecting the liver from bacterial infections and serve as gatekeepers.

• Cryovial: ~0.5×10⁶ to ~1.0×10⁶

Tempo-iKupffer™ are reprogrammed from human iPSCs, using integration-free induced pluripotent stem cell (iPSC) lines under a fully defined proprietary serum-free, virus-free, nucleic-acids-free, and integration-free conditions.

They express the following biomarkers using RT/q-PCR and Immunocytochemistry (ICC) methods: CD163, CD206, NR1H3, SpiC, CD68, S100AB.

Intended for scientific research, drug discovery and therapeutics development use only. It is not a product for human testing or diagnostics.

Long-term storage: liquid nitrogen
Growth Properties: 2D/monolayer cell culture technique; 3D/spheroid/organoid cell culture techniques
QC: Sterility, safety (BioSafety Level 2), HIV/viruses, bacteria, fungi: negative. Cell viability post-thawing (>85%)